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1.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF UTILIZING ARYLPIPERAZINE DERIVATIVES 审中-公开组合物，合成和使用芳香族苯并吡喃衍生物的方法
公开(公告)号：WO2010099502A1
公开(公告)日：2010-09-02
申请号：PCT/US2010/025687
申请日：2010-02-26
Applicant: REVIVA PHARMACEUTICALS, INC. , BHAT, Laxminarayan , MOHAPATRA, Prabhu, Prasad , ADIEY, Kouacou
Inventor： BHAT, Laxminarayan , MOHAPATRA, Prabhu, Prasad , ADIEY, Kouacou
IPC: A61K31/497
CPC classification number: C07D265/36 , A61K31/538 , C07D413/12
Abstract: The present invention provides arylpiperazine derivatives which can be advantageously used for treating schizophrenia and related psychoses such as acute manic, bipolar disorder, autistic disorder and depression.
Abstract translation: 本发明提供了可有利地用于治疗精神分裂症和相关精神病例如急性躁狂症，双相情感障碍，自闭症和抑郁症的芳基哌嗪衍生物。
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公开(公告)号：WO2016115144A1
公开(公告)日：2016-07-21
申请号：PCT/US2016/013061
申请日：2016-01-12
Applicant: REVIVA PHARMACEUTICALS INC.
Inventor： BHAT, Laxminarayan , CANTILLON, Marc , BHAT, Seema Rani
IPC: A61K31/538
CPC classification number: A61K31/538 , A61K9/0053
Abstract: The present invention provides a method of using arylpiperazine derivatives for treating behavioral and psychological symptoms in Alzheimer's disease patients. The method comprises a step of administering to a patient in need thereof an effective amount of a compound of Formula 1, which is an arylpiperazine derivative.
Abstract translation: 本发明提供了使用芳基哌嗪衍生物治疗阿尔茨海默病患者的行为和心理症状的方法。 该方法包括向有需要的患者施用有效量的作为芳基哌嗪衍生物的式1化合物的步骤。
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公开(公告)号：WO2016115039A1
公开(公告)日：2016-07-21
申请号：PCT/US2016/012873
申请日：2016-01-11
Applicant: REVIVA PHARMACEUTICALS INC.
Inventor： BHAT, Laxminarayan , CANTILLON, Marc , WALLIS, Ellen M. , BHAT, Seema Rani
IPC: A61K31/538
CPC classification number: A61K31/538 , A61P9/12 , A61P25/22 , A61P25/24
Abstract: The present invention provides a method of using arylpiperazine derivatives for treating pulmonary hypertension. The method comprises a step of administering to a patient in need thereof an effective amount of a compound of Formula I, which is an arylpiperazine derivative. A method of treating pulmonary hypertension in a subject, the method comprising administering to a subject suffering from pulmonary hypertension an effective amount of a compound of Formula I.
Abstract translation: 本发明提供了使用芳基哌嗪衍生物治疗肺动脉高压的方法。 该方法包括向有需要的患者施用有效量的作为芳基哌嗪衍生物的式I化合物的步骤。 一种治疗受试者的肺动脉高压的方法，所述方法包括向患有肺动脉高压的受试者施用有效量的式I化合物。
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4.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES 审中-公开组合物，合成方法和使用苯基甲基吗啉衍生物的方法
公开(公告)号：WO2013102195A1
公开(公告)日：2013-07-04
申请号：PCT/US2012/072283
申请日：2012-12-31
Applicant: REVIVA PHARMACEUTICALS, INC.
Inventor： BHAT, Laxminarayan , ADIEY, Kouacou , BHAT, Seema Rani
IPC: C07C211/26 , C07C211/25 , A61K31/13 , A61P3/04 , A61P25/24
CPC classification number: C07C317/28 , C07C211/27 , C07C211/29 , C07C217/08 , C07C217/74 , C07C317/18 , C07C317/50 , C07C323/25 , C07C323/32 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D207/09 , C07D211/34
Abstract: The present invention provides novel phenylcycloalkylmethylamme derivatives, and methods of preparing phenylcycloalkylmethylamme derivatives. The present invention also provides methods of using phenylcycloalkylmethylamme derivatives and compositions of phenylcycloalkylmethylamme derivatives. The pharmaceutical compositions of the compounds of the present invention can be used for treating and/or preventing obesity and obesity related co- morbid indications and depression and depression related co-morbid indications.
Abstract translation: 本发明提供新的苯基环烷基甲基胺衍生物，以及制备苯基环烷基甲基胺衍生物的方法。 本发明还提供使用苯基环烷基甲基胺衍生物和苯基环烷基甲基胺衍生物的组合物的方法。 本发明化合物的药物组合物可用于治疗和/或预防肥胖和肥胖相关并发病症适应症和抑郁症和抑郁症相关并发症的适应症。
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5.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES 审中-公开组合物，合成和使用环丙基甲基胺衍生物的方法
公开(公告)号：WO2012003501A3
公开(公告)日：2012-03-29
申请号：PCT/US2011042887
申请日：2011-07-01
Applicant: REVIVA PHARMACEUTICALS INC , BHAT LAXMINARAYAN , ADIEY KOUACOU
Inventor： BHAT LAXMINARAYAN , ADIEY KOUACOU
IPC: C12P7/64
CPC classification number: C07C69/34 , C07C69/96 , C07C209/48 , C07C209/88 , C07C211/26 , C07C213/06 , C07C213/10 , C07C217/74 , C07C219/06 , C07C229/34 , C07C231/02 , C07C237/06 , C07C237/22 , C07C271/20 , C07C2601/04
Abstract: The present invention provides novel cycloalkylmethylamme derivatives, and methods of preparing cycloalkylmethylamme derivatives. The present invention also provides methods of using cycloalkylmethylamme derivatives and compositions of cycloalkylmethylamme derivatives. The pharmaceutical compositions of the compounds of the present invention can be advantageously used for treating and/or preventing obesity and obesity related co-morbid indications and depression and depression related co-morbid indications.
Abstract translation: 本发明提供新的环烷基甲基胺衍生物，以及环烷基甲基胺衍生物的制备方法。 本发明还提供了使用环烷基甲基胺衍生物和环烷基甲基胺衍生物的组合物的方法。 本发明化合物的药物组合物可以有利地用于治疗和/或预防肥胖和肥胖相关并发症适应症和抑郁症和抑郁症相关并发症的适应症。
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Patent Agency Ranking6.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF USING CYCLOALKYLMETHYLAMINE DERIVATIVES 审中-公开环烷基甲基胺衍生物的组成，合成及使用方法
公开(公告)号：WO2012003501A2
公开(公告)日：2012-01-05
申请号：PCT/US2011/042887
申请日：2011-07-01
Applicant: REVIVA PHARMACEUTICALS, INC. , BHAT, Laxminarayan , ADIEY, Kouacou
Inventor： BHAT, Laxminarayan , ADIEY, Kouacou
IPC: C12P7/64
CPC classification number: C07C69/34 , C07C69/96 , C07C209/48 , C07C209/88 , C07C211/26 , C07C213/06 , C07C213/10 , C07C217/74 , C07C219/06 , C07C229/34 , C07C231/02 , C07C237/06 , C07C237/22 , C07C271/20 , C07C2601/04
Abstract: The present invention provides novel cycloalkylmethylamme derivatives, and methods of preparing cycloalkylmethylamme derivatives. The present invention also provides methods of using cycloalkylmethylamme derivatives and compositions of cycloalkylmethylamme derivatives. The pharmaceutical compositions of the compounds of the present invention can be advantageously used for treating and/or preventing obesity and obesity related co-morbid indications and depression and depression related co-morbid indications.
Abstract translation: 本发明提供了新的环烷基甲基胺衍生物，以及制备环烷基甲基胺衍生物的方法。 本发明还提供了使用环烷基甲基胺衍生物和环烷基甲基胺衍生物组合物的方法。 本发明化合物的药物组合物可以有利地用于治疗和/或预防肥胖症和肥胖症相关的共病迹象以及抑郁症和抑郁症相关的共病症状。
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7.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF UTILIZING QUINAZOLINEDIONE DERIVATIVES 审中-公开组合物，合成方法和使用喹唑啉衍生物的方法
公开(公告)号：WO2010099503A1
公开(公告)日：2010-09-02
申请号：PCT/US2010/025688
申请日：2010-02-26
Applicant: REVIVA PHARMACEUTICALS, INC. , BHAT, Laxminarayan , MOHAPATRA, Prabhu, Prasad , DADIBOYENA, Sureshbabu , ADIEY, Kouacou
IPC: A01N43/54 , A61K31/517
CPC classification number: C07D265/36 , A61K31/538 , C07D413/12
Abstract: The present invention provides quinazolinedione derivatives which can be advantageously used for treating schizophrenia and related psychoses such as acute manic, bipolar disorder, autistic disorder, depression and dementia.
Abstract translation: 本发明提供可有利地用于治疗精神分裂症和相关精神病如急性躁狂症，双相情感障碍，自闭症，抑郁和痴呆的喹唑啉二酮衍生物。
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8.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES 审中-公开组合物，合成方法和使用苯基甲基吗啉衍生物的方法
公开(公告)号：WO2013102195A8
公开(公告)日：2014-02-13
申请号：PCT/US2012072283
申请日：2012-12-31
Applicant: REVIVA PHARMACEUTICALS INC
Inventor： BHAT LAXMINARAYAN , ADIEY KOUACOU , BHAT SEEMA RANI
IPC: C07C211/26 , A61K31/13 , A61P3/04 , A61P25/24 , C07C211/25
CPC classification number: C07C317/28 , C07C211/27 , C07C211/29 , C07C217/08 , C07C217/74 , C07C317/18 , C07C317/50 , C07C323/25 , C07C323/32 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D207/09 , C07D211/34
Abstract: The present invention provides novel phenylcycloalkylmethylamine derivatives, and methods of preparing phenylcycloalkylmethylamine derivatives. The present invention also provides methods of using phenylcycloalkylmethylamine derivatives and compositions of phenylcycloalkylmethylamine derivatives. The pharmaceutical compositions of the compounds of the present invention can be used for treating and/or preventing obesity and obesity related co-morbid indications and depression and depression related co-morbid indications.
Abstract translation: 本发明提供新的苯基环烷基甲基胺衍生物，以及制备苯基环烷基甲基胺衍生物的方法。 本发明还提供使用苯基环烷基甲基胺衍生物和苯基环烷基甲胺衍生物的组合物的方法。 本发明化合物的药物组合物可用于治疗和/或预防肥胖和肥胖相关并发症适应症和抑郁症和抑郁症相关并发症的适应症。
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9.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PIPERAZINE BASED ANTIPSYCHOTIC AGENTS 审中-公开使用基于哌啶的抗生素代谢物的组合物，合成方法和方法
公开(公告)号：WO2009154993A8
公开(公告)日：2010-02-25
申请号：PCT/US2009045320
申请日：2009-05-27
Applicant: REVIVA PHARMACEUTICALS INC , BHAT LAXMINARAYAN , MOHAPATRA PRABHU PRASAD , ADIEY KOUACOU
Inventor： BHAT LAXMINARAYAN , MOHAPATRA PRABHU PRASAD , ADIEY KOUACOU
IPC: A01N43/00
CPC classification number: C07D265/36 , C07D239/96
Abstract: The present invention provides novel piperazine derivatives which can be advantageously used for treating schizophrenia and related psychoses such as acute manic, bipolar disorder, autistic disorder and depression.
Abstract translation: 本发明提供了可用于治疗精神分裂症和相关精神病如急性躁狂症，双相情感障碍，自闭症和抑郁症的新型哌嗪衍生物。
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10.发明申请COMPOSITIONS, SYNTHESIS, AND METHODS OF USING INDANONE BASED CHOLINESTERASE INHIBITORS 审中-公开使用基于INDANONE的胆碱酯酶抑制剂的组合物，合成方法和方法
公开(公告)号：WO2008073452A8
公开(公告)日：2009-01-22
申请号：PCT/US2007025392
申请日：2007-12-11
Applicant: REVIVA PHARMACEUTICALS INC , BHAT LAXMINARAYAN , MOHAPATRA PRABHU PRASAD
Inventor： BHAT LAXMINARAYAN , MOHAPATRA PRABHU PRASAD
IPC: A01N55/02 , A61K31/555
CPC classification number: C07D211/22 , C07D401/06 , C07D401/12
Abstract: The present invention provides novel indanone derivatives which can be advantageously used for treating and/ or preventing of a medical condition for which inhibition of a cholinesterase is desired.
Abstract translation: 本发明提供了可有利地用于治疗和/或预防需要抑制胆碱酯酶的医学病症的新型茚酮衍生物。
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