公开(公告)号：WO2014032256A1

公开(公告)日：2014-03-06

申请号：PCT/CN2012/080790

申请日：2012-08-30

Applicant: GENERAL ELECTRIC COMPANY ,  ZHU, Huibin ,  RITTER, Allen Michael ,  LARSEN, Einar Vaughn ,  KLODOWSKI, Anthony Michael ,  TAN, Zhuohui ,  YANG, Wenqiang ,  BARKER, Sidney Allen ,  WU, Xueqin

Inventor： ZHU, Huibin ,  RITTER, Allen Michael ,  LARSEN, Einar Vaughn ,  KLODOWSKI, Anthony Michael ,  TAN, Zhuohui ,  YANG, Wenqiang ,  BARKER, Sidney Allen ,  WU, Xueqin

IPC: H02H7/06

CPC classification number: H02H3/207 ,  F03D7/0284 ,  H02H3/025 ,  H02H7/06 ,  H02J3/386 ,  H02J2003/001 ,  H02P9/007 ,  H02P9/10 ,  Y02E10/723 ,  Y02E10/763

Abstract: A system and method for protecting one or more electrical machines during a grid fault on an electrical system connected with the one or more electrical machines. The method includes detecting the grid fault on the electrical system(402); taking one or more first actions from a first set of actions based on the detected grid fault on the electrical system(404); detecting at least one operating condition of the electrical system after taking one or more first actions from the first set of actions based on the detected grid fault on the electrical system(406); and taking one or more second actions from a second set of actions based on the detected at least one operating condition of the electrical system(408).

Abstract translation: 一种用于在与一个或多个电机连接的电气系统上的电网故障期间保护一个或多个电机的系统和方法。 该方法包括检测电气系统（402）上的电网故障; 基于电气系统（404）上检测到的电网故障，从第一组动作中获取一个或多个第一动作; 在基于所述电气系统（406）上检测到的电网故障从所述第一组动作采取一个或多个第一动作之后，检测所述电气系统的至少一个操作条件; 以及基于所检测到的所述电气系统的至少一个操作条件（408）从第二组动作获取一个或多个第二动作。

公开(公告)号：WO2014032249A1

公开(公告)日：2014-03-06

申请号：PCT/CN2012/080763

申请日：2012-08-30

Applicant: GENERAL ELECTRIC COMPANY ,  ZHU, Huibin ,  RITTER, Allen Michael ,  LARSEN, Einar Vaughn ,  KLODOWSKI, Anthony Michael ,  BARKER, Sidney Allen ,  WU, Xueqin ,  CHANG, Shouzhong

Inventor： ZHU, Huibin ,  RITTER, Allen Michael ,  LARSEN, Einar Vaughn ,  KLODOWSKI, Anthony Michael ,  BARKER, Sidney Allen ,  WU, Xueqin ,  CHANG, Shouzhong

IPC: H02J3/38 ,  H02H7/26

CPC classification number: H02H7/06 ,  F03D9/255 ,  F03D17/00 ,  G01R19/165 ,  G01R21/00 ,  G01R25/00 ,  H02J3/38 ,  H02J3/386 ,  H02J2003/388 ,  Y02E10/763

Abstract: In one aspect, a method for protecting one or more electrical machines during an islanding event is provided. The method includes connecting one or more electrical machines to an alternating current (AC) electric power system, wherein the AC electric power system is configured to transmit at least one phase of electrical power to the one or more electrical machines or to receive at least on phase of electrical power from the one or more electrical machines; electrically coupling at least a portion of a control system to at least a portion of the AC electric power system; coupling at least a portion of the control system in electronic data communication with at least a portion of the one or more electrical machines; and detecting an islanding of the one or more electrical machines based on one or more conditions monitored by the control system.

Abstract translation: 一方面，提供了在孤岛事件期间保护一个或多个电机的方法。 该方法包括将一个或多个电机连接到交流（AC）电力系统，其中交流电力系统被配置为将至少一个电力相位发射到一个或多个电机或者至少接收 来自一个或多个电机的电力相位; 将控制系统的至少一部分电耦合到AC电力系统的至少一部分; 将所述控制系统的至少一部分与电子数据通信耦合到所述一个或多个电机的至少一部分; 以及基于由所述控制系统监视的一个或多个条件来检测所述一个或多个电机的孤岛。

公开(公告)号：WO2012155297A1

公开(公告)日：2012-11-22

申请号：PCT/CN2011/000867

申请日：2011-05-18

Applicant: GENERAL ELECTRIC COMPANY ,  ZHU, Huibin ,  SMITH, David ,  GONG, Maozhong ,  ZHU, Jun ,  RITTER, Allen ,  WAGONER, Robert Gregory ,  GALBRAITH, Anthony ,  WU, Xueqin ,  ZHANG, Qiwel

Inventor： ZHU, Huibin ,  SMITH, David ,  GONG, Maozhong ,  ZHU, Jun ,  RITTER, Allen ,  WAGONER, Robert Gregory ,  GALBRAITH, Anthony ,  WU, Xueqin ,  ZHANG, Qiwel

IPC: H02M7/00

CPC classification number: H02H7/1203 ,  H02M3/1584 ,  H02M7/53871 ,  H02M2001/0003 ,  H02M2001/007

Abstract: A power converter system (100) includes a converter (128) configured to be coupled to a power generation unit (102) for receiving power from the power generation unit, and a bus (132) coupled to the converter, wherein a voltage is generated across the bus when electricity is conducted through the power converter system. The power converter system also includes an inverter (130) coupled to the bus, wherein the inverter is configured to supply power to an electrical distribution network (106). A control system (164) is coupled to at least one of the converter and the inverter, wherein the control system is configured to adjust an operation of at least one of the converter and the inverter to reduce the voltage across the bus during at least one of a low voltage event and a high voltage event.

Abstract translation: 功率转换器系统（100）包括被配置为耦合到用于从发电单元接收功率的发电单元（102）的转换器（128）和耦合到转换器的总线（132），其中产生电压 通过电力转换器系统进行电力通过总线。 功率转换器系统还包括耦合到总线的逆变器（130），其中逆变器被配置为向配电网络（106）供电。 控制系统（164）耦合到转换器和逆变器中的至少一个，其中控制系统被配置成调整转换器和逆变器中的至少一个的操作，以在至少一个 的低电压事件和高电压事件。

公开(公告)号：WO2011064277A2

公开(公告)日：2011-06-03

申请号：PCT/EP2010/068164

申请日：2010-11-24

Applicant: NUOVO PIGNONE S.p.A. ,  RITTER, Allen ,  ZHANG, Richard ,  WANG, Changyong ,  SCHROEDER, Stefan ,  ZHANG, Fan ,  BACCANI, Roberto

Inventor： RITTER, Allen ,  ZHANG, Richard ,  WANG, Changyong ,  SCHROEDER, Stefan ,  ZHANG, Fan ,  BACCANI, Roberto

IPC: H02M5/458

CPC classification number: H02M5/458

Abstract: A drive device and method for controlling a rotating machine. The drive device includes plural inverters configured to transform first alternate currents (AC); DC links connected to the plural inverters and configured to transmit the DC currents; plural converters connected to the DC links and configured to transform the DC currents received from the DC links to second AC currents, where the plural converters are connected in series; semiconductor switches configured to switch the second AC currents and to sustain a short circuit during a failed mode, the semiconductor switches being provided inside the plural converters; and a controller connected to gates of the semiconductor switches and configured to switch on and off, when a semiconductor switch in a converter is in a failed mode, remaining semiconductor switches in the converter such that an AC current passes the converter.

Abstract translation: 一种用于控制旋转机器的驱动装置和方法。 驱动装置包括多个反相器，被配置为变换第一交流电流（AC）; 连接到多个反相器并被配置为传送DC电流的DC链路; 多个转换器，其连接到所述DC链路并且被配置为将从所述DC链路接收的DC电流变换为第二AC电流，其中所述多个转换器串联连接; 半导体开关被配置为在故障模式期间切换第二AC电流并维持短路，半导体开关设置在多个转换器内部; 以及连接到半导体开关的栅极并被配置为接通和关断的控制器，当转换器中的半导体开关处于故障模式时，转换器中剩余的半导体开关使得交流电流通过转换器。

公开(公告)号：WO2011064277A3

公开(公告)日：2013-04-04

申请号：PCT/EP2010068164

申请日：2010-11-24

Applicant: NUOVO PIGNONE SPA ,  RITTER ALLEN ,  ZHANG RICHARD ,  WANG CHANGYONG ,  SCHROEDER STEFAN ,  ZHANG FAN ,  BACCANI ROBERTO

Inventor： RITTER ALLEN ,  ZHANG RICHARD ,  WANG CHANGYONG ,  SCHROEDER STEFAN ,  ZHANG FAN ,  BACCANI ROBERTO

IPC: H02M5/458

CPC classification number: H02M5/458

Abstract: A drive device and method for controlling a rotating machine. The drive device includes plural inverters (60) configured to transform first alternate currents, AC; DC links (62a, 62b)connected to the plural inverters (60) and configured to transmit the DC currents; plural converters (64) connected to the DC links (62a, 62b) and configured to transform the DC currents received from the DC links (62a, 62b) to second AC currents, where the plural converters (64) are connected in series; semiconductor switches (68) configured to switch the second AC currents and to sustain a short circuit during a failed mode, the semiconductor switches (68) being provided inside the plural converters (64); and a controller (80) connected to gates (72) of the semiconductor switches (68) and configured to switch on and off, when a semiconductor switch (68) in a converter (64) is in a failed mode, remaining semiconductor switches (68) in the converter (64) such that an AC current passes the converter (64).

Abstract translation: 一种用于控制旋转机器的驱动装置和方法。 驱动装置包括多个反相器（60），被配置为转换第一交流电流AC; 连接到所述多个逆变器（60）并被配置为传送所述DC电流的DC链路（62a，62b） 多个转换器（64），其连接到所述DC链路（62a，62b），并且被配置为将从所述DC链路（62a，62b）接收的DC电流变换为所述多个转换器（64）串联连接的第二AC电流; 半导体开关（68）被配置为在故障模式期间切换第二AC电流并维持短路，半导体开关（68）设置在多个转换器（64）内部; 以及连接到半导体开关（68）的门（72）并且被配置为当转换器（64）中的半导体开关（68）处于故障模式时）接通和断开的控制器（80），剩余半导体开关 68），使得AC电流通过转换器（64）。

公开(公告)号：WO2012142281A1

公开(公告)日：2012-10-18

申请号：PCT/US2012/033312

申请日：2012-04-12

Applicant: ENDOCYTE, INC. ,  RITTER, Allen ,  WILLIAMS, Amy C. ,  WALDMANN, Lars ,  ZHANG, Huamin

Inventor： RITTER, Allen ,  WILLIAMS, Amy C. ,  WALDMANN, Lars ,  ZHANG, Huamin

IPC: A01N43/64 ,  A61K31/53 ,  A61K9/48 ,  A61K9/14

CPC classification number: A61K38/08 ,  A61J1/00 ,  A61K9/0019 ,  A61K9/10 ,  A61K9/19 ,  A61K31/475 ,  A61K31/53 ,  A61K31/704 ,  A61K47/26 ,  A61K2300/00

Abstract: The invention described herein pertains to a solid pharmaceutical composition comprising EC145 for reconstitution to provide a solution for intravenous injection, particularly to a lyophilized solid pharmaceutical composition comprising EC145 which has adequate stability for storage at ambient temperature and which is capable of redissolving in an aqueous diluent prior to administration, as well as a process for its manufacture, drug products comprising the composition and methods for using the composition for treating cancer.

Abstract translation: 本文描述的本发明涉及包含EC145的固体药物组合物，其用于重建以提供用于静脉内注射的溶液，特别是涉及包含EC145的冻干固体药物组合物，所述固体药物组合物在环境温度下具有足够的稳定性用于储存并且能够再溶解于水性稀释剂 在给药之前，以及其制备方法，包含组合物的药物产品和使用该组合物治疗癌症的方法。

公开(公告)号：WO2012019123A1

公开(公告)日：2012-02-09

申请号：PCT/US2011/046797

申请日：2011-08-05

Applicant: ENDOCYTE, INC. ,  VLAHOV, Iontcho, Radoslavov ,  GROANING, Michael ,  KLEINDL, Paul, Joseph ,  SANTHAPURAM, Hari Krishna, R. ,  YOU, Fei ,  WANG, Yu ,  XU, Le-cun ,  STANFORD, Katheryn, Marie ,  RITTER, Allen ,  LEAMON, Christopher, Paul

Inventor： VLAHOV, Iontcho, Radoslavov ,  GROANING, Michael ,  KLEINDL, Paul, Joseph ,  SANTHAPURAM, Hari Krishna, R. ,  YOU, Fei ,  WANG, Yu ,  XU, Le-cun ,  STANFORD, Katheryn, Marie ,  RITTER, Allen ,  LEAMON, Christopher, Paul

IPC: A61K31/445

CPC classification number: C12P21/00 ,  A61K31/445 ,  C07D417/12 ,  C07K5/02 ,  C07K5/021

Abstract: Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.

Abstract translation: Tubulysins是一系列作为抗癌治疗剂感兴趣的天然存在的细胞毒性剂。 描述了可用于制备天然存在和非天然存在的管状体及其类似物及其衍生物的方法和中间体。