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公开(公告)号：WO2007087560A3
公开(公告)日：2008-09-25
申请号：PCT/US2007060965
申请日：2007-01-24
Applicant: UNIV ILLINOIS , ROUSCHE PATRICK J , CHIGANOS TERRY C JR , JENSEN WINNIE
Inventor： ROUSCHE PATRICK J , CHIGANOS TERRY C JR , JENSEN WINNIE
CPC classification number: A61B5/04001 , A61B5/4041 , A61B18/22 , A61B2560/0443 , A61N1/0531 , A61N1/0536 , A61N1/36103 , A61N1/38
Abstract: The present invention is a system and method for realtime monitoring of neural responses to stroke. The system of the present invention provides a component for inducing a localized stroke and one or more sensors for monitoring molecular and cellular physiological events before, during and after the stroke. Methods for inducing a stroke, monitoring neural responses, and identifying neuroprotective strategies and/or agents with a model are also provided.
Abstract translation: 本发明是用于实时监测中风的神经反应的系统和方法。 本发明的系统提供用于诱导局部卒中的组件和用于在卒中之前，之中和之后监测分子和细胞生理事件的一个或多个传感器。 还提供了诱导中风的方法，监测神经反应以及用模型鉴定神经保护策略和/或代理。
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公开(公告)号：WO0172201A3
公开(公告)日：2008-02-21
申请号：PCT/US0110032
申请日：2001-03-29
Applicant: UNIV ARIZONA , KIPKE DARYL , WILLIAMS JUSTIN , ROUSCHE PATRICK , PELLINEN DAVID S , PIVIN DAVID
Inventor： KIPKE DARYL , WILLIAMS JUSTIN , ROUSCHE PATRICK , PELLINEN DAVID S , PIVIN DAVID
CPC classification number: A61N1/0531 , A61B5/04001 , A61B5/4041 , A61B5/4047 , A61B5/685 , A61B2562/187 , Y10S977/936 , Y10T29/49117
Abstract: An implant device (500) for creating a neural interface with the central nervous system having a polyimide-based electrode arra (520) is presented along with a method for making the device. The device may be configured as a three dimensional structure (600) and is capable of sensing multi-unit neural activity from the cerebral cortex. Mechanical, electrical and biological characteristics of the device support it use as a reliable, long term implant.
Abstract translation: 与用于制造该装置的方法一起呈现用于与具有基于聚酰亚胺的电极（520）的中枢神经系统产生神经界面的植入装置（500）。 该装置可以被配置为三维结构（600）并且能够感测来自大脑皮质的多单位神经活动。 该设备的机械，电气和生物特性支持其用作可靠的长期植入物。
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公开(公告)号：WO2007087560A2
公开(公告)日：2007-08-02
申请号：PCT/US2007/060965
申请日：2007-01-24
Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , ROUSCHE, Patrick, J. , CHIGANOS, Terry, C., Jr. , JENSEN, Winnie
Inventor： ROUSCHE, Patrick, J. , CHIGANOS, Terry, C., Jr. , JENSEN, Winnie
CPC classification number: A61B5/04001 , A61B5/4041 , A61B18/22 , A61B2560/0443 , A61N1/0531 , A61N1/0536 , A61N1/36103 , A61N1/38
Abstract: The present invention is a system and method for realtime monitoring of neural responses to stroke. The system of the present invention provides a component for inducing a localized stroke and one or more sensors for monitoring molecular and cellular physiological events before, during and after the stroke. Methods for inducing a stroke, monitoring neural responses, and identifying neuroprotective strategies and/or agents with a model are also provided.
Abstract translation: 本发明是用于实时监测中风的神经反应的系统和方法。 本发明的系统提供用于诱导局部卒中的组件和用于在卒中之前，之中和之后监测分子和细胞生理事件的一个或多个传感器。 还提供了诱导中风的方法，监测神经反应以及用模型鉴定神经保护策略和/或代理。
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