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    ACTIVE INGREDIENT FOR HOMOGENIZING COMPLEXION, IN PARTICULAR SKINS WITH AN OLIVE CARNATION
    2.
    发明申请
    ACTIVE INGREDIENT FOR HOMOGENIZING COMPLEXION, IN PARTICULAR SKINS WITH AN OLIVE CARNATION 审中-公开

    公开(公告)号：WO2020165365A1

    公开(公告)日：2020-08-20

    申请号：PCT/EP2020/053800

    申请日：2020-02-13

    Applicant: SEDERMA

    Inventor： RINGENBACH, Caroline ,  ROUYER, Nathalie ,  GRACIOSO, Olga

    IPC: A61K8/9789 ,  A61Q19/02

    Abstract: The invention provides the use of undifferentiated or dedifferentiated plant cells, whole and/or lysed, from Buddleja davidii Franch. obtained by an in vitro cell culture process, and/or an intracellular extract of said cells free of cellular debris, for a topical non-therapeutic cosmetic treatment to homogenize the complexion of the skin, in particular via prevention and/or treatment of pigment and/or skin texture heterogeneities. The treatment is particularly suitable for the treatment of skins of phototype III to V developing spots and areas of hyperpigmentation, and furthermore especially for the treatment of skin with olive carnation.

    TOPICAL SLIMMING COSMETIC TREATMENT
    3.
    发明申请
    TOPICAL SLIMMING COSMETIC TREATMENT 审中-公开
    局部瘦身化妆品治疗

    公开(公告)号：WO2018060148A1

    公开(公告)日：2018-04-05

    申请号：PCT/EP2017/074265

    申请日：2017-09-25

    Applicant: SEDERMA

    Inventor： MONDON, Philippe

    IPC: A61Q19/06 ,  A61K8/49 ,  A61K8/97

    CPC classification number: A61Q19/06 ,  A61K8/4973 ,  A61K8/97

    Abstract: The use at least one alkyl phthalide or a plant extract comprising said at least one alkyl phthalide as the major component for a topical cosmetic slimming treatment. According to the invention, it is possible in particular to use a CO2 supercritical extract of seeds of Apium graveolens comprising sedanenolide as the major alkyl phthalide.

    Abstract translation: 使用至少一种烷基苯酞或包含所述至少一种烷基苯酞的植物提取物作为用于局部美容减肥处理的主要组分。 根据本发明，特别可以使用包含sedanenolide的芹菜种子的CO2超临界提取物作为主要烷基苯酞。

    PRO-PIGMENTING PEPTIDES
    5.
    发明申请
    PRO-PIGMENTING PEPTIDES 审中-公开
    专用胶原蛋白（Pro-PIGMENTING PEPTIDES）

    公开(公告)号：WO2014080376A2

    公开(公告)日：2014-05-30

    申请号：PCT/IB2013060390

    申请日：2013-11-25

    Applicant: SEDERMA SA

    Inventor： PESCHARD OLIVIER ,  MONDON PHILIPPE

    IPC: C07K5/103 ,  A61K38/00 ,  C07K5/062 ,  C07K5/078 ,  C07K5/083 ,  C07K5/087 ,  C07K5/093 ,  C07K5/097

    CPC classification number: A61K8/64 ,  A61K38/00 ,  A61K2800/74 ,  A61Q5/10 ,  A61Q19/007 ,  A61Q19/04 ,  A61Q19/08 ,  C07K5/06026 ,  C07K5/06165 ,  C07K5/0806 ,  C07K5/0808 ,  C07K5/081 ,  C07K5/0812 ,  C07K5/0819 ,  C07K5/0821 ,  C07K5/1008

    Abstract: The invention is directed to the use of at least one peptide of formula: X –(Xaa1 ) n –Pro* –(Xaa2)m –Y (I) With: -n = 0, 1 or 2; -m =0 or 1and if m = 0 then n ≠ 0 -Xaa is: -An hydrophobic aminoacid selected from Alanine (Ala, A), Valine (Val, V), Methionine (Met, M), Leucine (Leu, L), Isoleucine (Ile, I), Phenylalanine (Phe, F), Proline (Pro, P) and analogues and derivatives thereof; -A polar aminoacid selected from Serine (Ser, S), Threonine (Thr, T), Tyrosine (Tyr, Y), Asparagine (Asn, N), Glutamine (Gln, Q)and analogues and derivatives thereof; or -Glycine (Gly, G); When n = 2 the two aminoacids Xaa1 can be the same or different; -Xaa2 is: -An hydrophobic aminoacid selected from Alanine (Ala, A), Valine (Val, V), Methionine (Met, M), Leucine (Leu, L), Isoleucine (Ile, I), Phenylalanine (Phe, F), Proline (Pro, P) and analogues and derivatives thereof; -A basic aminoacid selected from Arginine (Arg, R), Lysine (Lys, K) and Histidine (His, H) and analogues and derivatives thereof; -Glycine (Gly, G) or Serine (Ser, S); -At the N terminal end of the peptide, X is selected from H, -CO-R1 and -SO2 -R1; -At the C terminal end of the peptide, Y is selected from OH, OR1, NH2, NHR1 or NR1 R2, -R1 and R2 being independantly from each other, selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy and aryloxy group, that can be linear, branched, cyclic, poly-cyclic, non- saturated, hydroxylated, carbonylated, phosphorylated and/or sulphured, with the possibility to have in said group skeleton a O, S and/or N heteroatom; -Pro* corresponding to a Proline, an analogue or derivative thereof; Excluding the peptides where X=H and Y=OH, for a non therapeutical cosmetic pro-pigmenting treatment of skin. The invention also encompasses new tripeptides of formula (I) suitable for a non therapeutical cosmetic treatment of skin.

    Abstract translation: 本发明涉及至少一种式X-（Xaa1）n -Pro * - （Xaa2）m -Y（I）的肽，其中：-n = 0,1或2; -m = 0或1，如果m = 0，那么n≠0 -Xaa是： - 选自丙氨酸（Ala，A），缬氨酸（Val，V），甲硫氨酸（Met，M），亮氨酸（Leu，L）的疏水性氨基酸 ），异亮氨酸（Ile，I），苯丙氨酸（Phe，F），脯氨酸（Pro，P）及其类似物和衍生物; - 选自丝氨酸（Ser，S），苏氨酸（Thr，T），酪氨酸（Tyr，Y），天冬酰胺（Asn，N），谷氨酰胺（Gln，Q））及其类似物和衍生物的极性氨基酸; 或甘氨酸（Gly，G）; 当n = 2时，两个氨基酸Xaa1可以相同或不同; -Xaa2是：选自丙氨酸（Ala，A），缬氨酸（Val，V），甲硫氨酸（Met，M），亮氨酸（Leu，L），异亮氨酸（Ile，I），苯丙氨酸（Phe，F ），Proline（Pro，P）及其类似物及衍生物; - 选自精氨酸（Arg，R），赖氨酸（Lys，K）和组氨酸（His，H）及其类似物和衍生物的碱性氨基酸; 甘氨酸（Gly，G）或丝氨酸（Ser，S）; - 在肽的N末端，X选自H，-CO-R 1和-SO 2 -R 1; - 在肽的C末端，Y选自OH，OR1，NH2，NHR1或NR1R2，-R1和R2彼此独立地选自烷基，芳基，芳烷基，烷芳基，烷氧基和芳氧基 可以是直链，支链，环状，多环，非饱和​​，羟基化，羰基化，磷酸化和/或硫化，可能在所述基团骨架中具有O，S和/或N杂原子; -Pro *对应于脯氨酸，其类似物或衍生物; 排除其中X = H和Y = OH的肽，用于皮肤的非治疗化妆品前着色处理。 本发明还包括适用于非治疗性美容治疗皮肤的新型式（I）三肽。

    TOPICAL COMPOSITION COMPRISING BIOACTIVE SULFATED OLIGOSACCHARIDES AND COSMETIC USES
    6.
    发明申请
    TOPICAL COMPOSITION COMPRISING BIOACTIVE SULFATED OLIGOSACCHARIDES AND COSMETIC USES 审中-公开
    包含生物活性硫化寡糖和化妆用途的局部组合物

    公开(公告)号：WO2013144909A3

    公开(公告)日：2014-03-06

    申请号：PCT/IB2013052516

    申请日：2013-03-28

    Applicant: SEDERMA SA ,  GRIZAUD CLAIRE-MARIE

    Inventor： GRIZAUD CLAIRE-MARIE

    IPC: A61K8/73 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

    CPC classification number: A61K8/73 ,  A61K8/60 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

    Abstract: The present invention provides a topical composition comprising: -A mixture of bioactive sulfated oligosaccharides having a degree of polymerisation (DP) comprised between 2 and 10, and -A physiologically acceptable medium; said oligosaccharides being obtained according to an enzymatic cleavage process according to a beta- elimination reaction of polysaccharides extracted from green algae of the ulvagenus comprising aldobiuronic sequences and glucuronan sequences using an ulvan-lyase enzyme adapted to cleave the osidic bond between the units of Glcp A Rhap3 sulfate and between the units Idop A and Rhap3, and using a glucuronan-lyase enzyme adapted to cleave the osidic bond between two Glcp A units. Such a composition has a particularly interesting cosmetic activity on the skin cells, including anti- inflammatory, anti-radical, de-pigmenting effects and effects on molecules of the dermal extracellular matrix (such as collagen 1, collagen 4 and fibronectin), on molecules of the epidermal extracellular matrix (hyaluronic acid). Applications: anti-aging and moisturizing

    Abstract translation: 本发明提供了一种局部组合物，其包含： - 具有2至10个聚合度（DP）的生物活性硫酸化寡糖和-A生理学上可接受的培养基的混合物; 所述寡糖是根据酶裂解方法获得的，根据从包含醛糖脱氢酶序列和葡糖苷酸序列的绿藻的绿藻中提取的多糖的β-去除反应，使用适于切割Glc A单位之间的osid键的ulvan-裂解酶 Rhap3硫酸盐和单位Idop A和Rhap3之间，并且使用适于切割两个Glcp A单元之间的键合键的葡萄糖醛酸酶裂解酶。 这种组合物对皮肤细胞具有特别有趣的美容活性，包括抗炎，抗自由基，去色素作用以及对分子的分子（例如胶原蛋白1，胶原蛋白4和纤连蛋白）对分子的影响 的表皮细胞外基质（透明质酸）。 应用：抗衰老和保湿

    COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES
    8.
    发明申请
    COSMETIC COMPOSITIONS COMPRISING ORIDONIN AND NEW COSMETIC USES 审中-公开
    包含ORIDONIN和新化妆品用途的化妆品组合物

    公开(公告)号：WO2010119423A2

    公开(公告)日：2010-10-21

    申请号：PCT/IB2010/051651

    申请日：2010-04-15

    Applicant: SEDERMA ,  FOURNIAL, Arnaud ,  MONDON, Philippe

    Inventor： FOURNIAL, Arnaud ,  MONDON, Philippe

    IPC: A61K8/34

    CPC classification number: A61Q19/08 ,  A61K8/347 ,  A61K8/498 ,  A61Q19/02

    Abstract: The present invention related to cosmetic compositions comprising oridonin and new cosmetic uses. Oridonin is used forfighting the signs of cutaneous ageingand for slimming. A composition comprising a combination of oridonin and darutigenol or a derivative thereof, in particular darutoside, is disclosed together with the cosmetic use of such composition.

    Abstract translation: 本发明涉及包含oridonin和新化妆品用途的化妆品组合物。 Oridonin用于治疗皮肤老化和减肥的迹象。 本发明公开了组合物，其组合物包含奥曲肽和达鲁必醇或其衍生物，特别是darutoside的组合，以及该组合物的美容用途。

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