公开(公告)号：WO2010075444A2

公开(公告)日：2010-07-01

申请号：PCT/US2009/069298

申请日：2009-12-22

Applicant: EVOKE PHARMA, INC. ,  D'ONOFRIO, Matthew, J. ,  GONYER, David, A. ,  SHAH, Shirish, A. ,  MADDEN, Stuart, J.

Inventor： D'ONOFRIO, Matthew, J. ,  GONYER, David, A. ,  SHAH, Shirish, A. ,  MADDEN, Stuart, J.

IPC: A61K31/165 ,  A61K9/12 ,  A61K9/20 ,  A61K31/14

CPC classification number: A61K31/166 ,  A61K9/0043 ,  A61K9/08 ,  A61K47/12 ,  A61M15/08

Abstract: Nasal formulations of metoclopramide, which remain stable and/or colorless upon storage over a period of time, are provided. Also provided are methods of treating disorders treatable with metoclopramide, comprising administering the nasal solutions to patients in need thereof.

Abstract translation: 提供了甲氧氯普胺的鼻制剂，其在一段时间内储存时保持稳定和/或无色。 还提供了治疗可用甲氧氯普胺治疗的病症的方法，包括向有需要的患者施用鼻溶液。

公开(公告)号：WO2010075444A3

公开(公告)日：2010-11-04

申请号：PCT/US2009069298

申请日：2009-12-22

Applicant: EVOKE PHARMA INC ,  D ONOFRIO MATTHEW J ,  GONYER DAVID A ,  SHAH SHIRISH A ,  MADDEN STUART J

Inventor： D ONOFRIO MATTHEW J ,  GONYER DAVID A ,  SHAH SHIRISH A ,  MADDEN STUART J

IPC: A61K31/165 ,  A61K9/12 ,  A61K9/20 ,  A61K31/14

CPC classification number: A61K31/166 ,  A61K9/0043 ,  A61K9/08 ,  A61K47/12 ,  A61M15/08

Abstract: Nasal formulations of metoclopramide, which remain stable and/or colorless upon storage over a period of time, are provided. Also provided are methods of treating disorders treatable with metoclopramide, comprising administering the nasal solutions to patients in need thereof.

Abstract translation: 提供了甲氧氯普胺的鼻用制剂，其在经过一段时间储存后保持稳定和/或无色。 还提供了治疗用甲氧氯普胺可治疗的病症的方法，其包括将鼻溶液施用于有需要的患者。

公开(公告)号：WO2005030460A3

公开(公告)日：2005-04-07

申请号：PCT/US2004/030880

申请日：2004-09-20

Applicant: MAGNECO/METREL, INC. ,  CONNORS, George ,  SHAH, Shirish

Inventor： CONNORS, George ,  SHAH, Shirish

IPC: B22C9/00

Abstract: A slurry composition for a mold and method of use thereof. The slurry composition includes about 45% to about 80% by weight alumina, about 10% to about 30% by weight silicon carbide, and about 10% to about 50% by weight colloidal silica. In one aspect, the alumina component comprises a material selected from the group consisting of brown fused alumina, white fused alumina, tabular alumina, calcined alumina, and mixtures thereof. In another aspect, the composition includes fumed silica at 2% to about 5% by weight. The composition may also include a setting agent at 0.05% to about 2% by weight.

公开(公告)号：WO2008157533A1

公开(公告)日：2008-12-24

申请号：PCT/US2008/067197

申请日：2008-06-17

Applicant: MAGNECO/METREL, INC. ,  CONNORS, Charles, W. ,  ANDERSON, Michael, W. ,  SHAH, Shirish

Inventor： CONNORS, Charles, W. ,  ANDERSON, Michael, W. ,  SHAH, Shirish

IPC: C03B5/00 ,  C04B35/101

CPC classification number: C03B5/43 ,  C04B28/24 ,  C04B35/106 ,  C04B35/66 ,  C04B2111/00146 ,  C04B2111/00551 ,  C04B2235/3217 ,  C04B2235/3244 ,  C04B2235/3418 ,  C04B2235/5427 ,  F27D1/0006 ,  C04B14/303 ,  C04B14/306 ,  C04B20/008

Abstract: A refractory composition includes a first set of components and a colloidal silica binder. The first set of components includes alumina and zirconia. The colloidal silica binder is provided at 5 wt % to 20 wt % of the dry weight of the first set of components. The refractory composition includes 45 wt % to 75 wt % alumina, 15 wt % to 30 wt % zirconia, and 10 wt % to 30 wt % silica.

Abstract translation: 耐火材料组合物包括第一组成分和胶体二氧化硅粘合剂。 第一组成分包括氧化铝和氧化锆。 提供胶体二氧化硅粘合剂，其为第一组成分的干重的5重量％至20重量％。 耐火材料组合物包括45重量％至75重量％的氧化铝，15重量％至30重量％的氧化锆和10重量％至30重量％的二氧化硅。

公开(公告)号：WO2005030460A2

公开(公告)日：2005-04-07

申请号：PCT/US2004030880

申请日：2004-09-20

Applicant: MAGNECO METREL INC ,  CONNORS GEORGE ,  SHAH SHIRISH

Inventor： CONNORS GEORGE ,  SHAH SHIRISH

IPC: B22C1/02 ,  B22C9/04 ,  B29C20060101 ,  B29C

CPC classification number: B22C1/183 ,  B22C1/00 ,  B22C1/02 ,  B22C1/181

Abstract: A slurry composition for a mold and method of use thereof. The slurry composition includes about 45% to about 80% by weight alumina, about 10% to about 30% by weight silicon carbide, and about 10% to about 50% by weight colloidal silica. In one aspect, the alumina component comprises a material selected from the group consisting of brown fused alumina, white fused alumina, tabular alumina, calcined alumina, and mixtures thereof. In another aspect, the composition includes fumed silica at 2% to about 5% by weight. The composition may also include a setting agent at 0.05% to about 2% by weight.

Abstract translation: 一种用于模具的浆料组合物及其使用方法。 浆料组合物包含约45重量％至约80重量％的氧化铝，约10重量％至约30重量％的碳化硅和约10重量％至约50重量％的胶体二氧化硅。 一方面，氧化铝组分包括选自棕色熔融氧化铝，白色熔融氧化铝，片状氧化铝，煅烧氧化铝及其混合物的材料。 在另一方面，组合物包含2重量％至约5重量％的煅制二氧化硅。 组合物还可以包含0.05％至约2％重量的凝固剂。