公开(公告)号：WO2006052682A3

公开(公告)日：2006-05-18

申请号：PCT/US2005/039839

申请日：2005-11-03

Applicant: APPLERA CORPORATION ,  OLDHAM, Mark, F. ,  MIRCHANDANI, Vinod, L. ,  HOSHIZAKI, Jon, A. ,  KING, Howard, G. ,  SLUIS, Johannes, P. ,  BOEGE, Steven, J.

Inventor： OLDHAM, Mark, F. ,  MIRCHANDANI, Vinod, L. ,  HOSHIZAKI, Jon, A. ,  KING, Howard, G. ,  SLUIS, Johannes, P. ,  BOEGE, Steven, J.

IPC: G02B26/10 ,  G01N21/64 ,  G05D23/00 ,  F21K7/00 ,  G01N33/53 ,  H05B33/08

Abstract: The present invention relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures. According to various embodyments, a system is provided that includes one or more LED (111), a temperature sensor (118), and a temperature regulator (122). The temperature. sensor can be in thermal contact with the LED (111), can be capable of measuring an operating temperature, and can be capable of generating an operating temperature signal. The temperature regulator can be capable of receiving an operating temperature signal of the LED and regulating the operating temperature based on the operating temperature signal. According to various embodiments, a method for illuminating a reaction region (108) with excitation beams is provided. The method can include providing a system (100) that includes an LED (111) and a reaction region (108). The method can include generating excitation beams with LED; directing the excitation beams toward the reaction region; measuring an operating temperature of the LED; and regulating the operating temperature by transferring heat away from and/or into the LED, based on the measured operating temperature. The reaction region includes a sample.

公开(公告)号：WO2006052682A2

公开(公告)日：2006-05-18

申请号：PCT/US2005039839

申请日：2005-11-03

Applicant: APPLERA CORP ,  OLDHAM MARK F ,  MIRCHANDANI VINOD L ,  HOSHIZAKI JON A ,  KING HOWARD G ,  SLUIS JOHANNES P ,  BOEGE STEVEN J

Inventor： OLDHAM MARK F ,  MIRCHANDANI VINOD L ,  HOSHIZAKI JON A ,  KING HOWARD G ,  SLUIS JOHANNES P ,  BOEGE STEVEN J

IPC: G02B26/10 ,  F21V9/16 ,  G01N21/01 ,  G01N21/64 ,  G01N33/53 ,  G05D23/00 ,  H05B33/08

CPC classification number: G01N21/64 ,  F21K9/00 ,  F21K9/64 ,  F21V29/54 ,  F21V29/677 ,  F21V29/74 ,  F21Y2115/10 ,  G01J3/0286 ,  G01J3/10 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6439 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/0638 ,  G01N2201/1211 ,  G05D23/1919 ,  G05D23/20

Abstract: Methods and optical systems for thermally compensated optical scanning of a target sample. The present invention also relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures.

Abstract translation: 用于目标样品的热补偿光学扫描的方法和光学系统。 本发明还涉及用于进行样品测定以及用于产生和测量光学响应和特征的方法和系统。