公开(公告)号：WO2004101481A1

公开(公告)日：2004-11-25

申请号：PCT/EP2004/050795

申请日：2004-05-13

申请人： SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. ,  DE JONG, Feike ,  SNEL, Johannes Jacobus Maria

发明人： DE JONG, Feike ,  SNEL, Johannes Jacobus Maria

IPC分类号： C07C29/76

CPC分类号： C07C29/095 ,  B01J41/02 ,  B01J41/04 ,  C07C29/76 ,  C07C31/202 ,  C07C31/205 ,  C07C31/36

摘要： The present invention relates to a process of removing organic halogen-containing compounds from a liquid stream mainly containing one or more of the compounds selected from the group consisting of glycol, water and alcohol, which process comprises contacting the stream with an ion-exchange material containing basic anions selected from the group of hydroxide, carbonate and bicarbonate.

摘要翻译： 本发明涉及从主要含有一种或多种选自二醇，水和醇的化合物的液体物流中除去有机含卤素化合物的方法，该方法包括使该物流与离子交换材料 含有选自氢氧根，碳酸根和碳酸氢根的碱性阴离子。

公开(公告)号：WO2008079009A1

公开(公告)日：2008-07-03

申请号：PCT/NL2007/050694

申请日：2007-12-21

申请人： Campina Nederland Holding B.V. ,  ZUURENDONK, Peter Frederik ,  KLEEREBEZEM, Michiel ,  SNEL, Johannes ,  MARCO, Maria ,  SAVELKOUL, Hubertus Franciscus Jozef

发明人： ZUURENDONK, Peter Frederik ,  KLEEREBEZEM, Michiel ,  SNEL, Johannes ,  MARCO, Maria ,  SAVELKOUL, Hubertus Franciscus Jozef

IPC分类号： A23L1/30 ,  C12N1/20 ,  C12R1/225 ,  C12R1/25

CPC分类号： C12R1/225 ,  A23C9/1234 ,  A23C15/123 ,  A23C19/0323 ,  A23L33/135 ,  A23V2002/00 ,  A23Y2220/67 ,  A61K35/747 ,  C12N1/20 ,  C12R1/25 ,  A23V2200/304 ,  A23V2200/3204

摘要： The present invention relates to immuno modulat ing probiotic lactic acid bacteria, to methods wherein the bacteria are used to reduce allergy, and to food products wherein the bacteria may be in incorporated to reduce allergy upon consumption of the product. Preferred probiotic lactic acid bacteria stimulate the Th1 and/or Th3 responses and/or represses Th2 responses as may be determined by the cytokine profiles that are induced in human peripheral blood mononuclear cells upon coincubation with the lactic acid bacteria.

摘要翻译： 本发明涉及免疫调节益生菌乳酸菌，其中使用细菌来减少过敏的方法，以及其中可以并入细菌以减少产品消费过敏的食品。 优选的益生菌乳酸细菌刺激Th1和/或Th3应答和/或镇压Th2应答，如通过与乳酸菌共调节时在人外周血单核细胞中诱导的细胞因子谱所确定的。

公开(公告)号：WO2011071370A1

公开(公告)日：2011-06-16

申请号：PCT/NL2010/050647

申请日：2010-10-05

申请人： CAMPINA NEDERLAND HOLDING B.V. ,  SNEL, Johannes ,  KLEEREBEZEM, Michiel ,  ZWIJSEN, Renate Maria Louise ,  SMIT, Bart ,  NOORDMAN, Wouter Herman

发明人： SNEL, Johannes ,  KLEEREBEZEM, Michiel ,  ZWIJSEN, Renate Maria Louise ,  SMIT, Bart ,  NOORDMAN, Wouter Herman

IPC分类号： A61K35/74 ,  C12N1/20

CPC分类号： A61K35/74 ,  C12N1/20

摘要： The present invention relates to immunomodulating probiotic lactic acid bacteria, to methods wherein the bacteria are used to reduce allergy, and to food products wherein the bacteria may be in incorporated to reduce allergy upon consumption of the product. Preferred probiotic lactic acid bacteria stimulate the Th1 and/or Th3 responses and/or represses Th2 responses in vivo asmay be determined by the cytokine profiles that are induced in humans upon consumption of the lactic acid bacteria.

摘要翻译： 本发明涉及免疫调节益生菌乳酸菌，其中细菌用于减少过敏的方法，以及其中可以并入细菌以减少产品消费过敏的食品。 优选的益生菌乳酸菌刺激Th1和/或Th3应答和/或抑制体内Th2应答，可以通过在消耗乳酸菌时在人体中诱导的细胞因子谱来确定。

公开(公告)号：WO2005090396A1

公开(公告)日：2005-09-29

申请号：PCT/NL2005/000216

申请日：2005-03-22

申请人： WAGENINGEN CENTRE FOR FOOD SCIENCES ,  PRETZER, Gabriele ,  SNEL, Johannes ,  BRON, Peter, Allard ,  DE VOS, Willem, Meindert ,  KLEEREBEZEM, Michiel

发明人： PRETZER, Gabriele ,  SNEL, Johannes ,  BRON, Peter, Allard ,  DE VOS, Willem, Meindert ,  KLEEREBEZEM, Michiel

IPC分类号： C07K14/335

CPC分类号： C07K14/335 ,  A61K38/00

摘要： The present invention relates to novel mannose-specific adhesins, and variants thereof, as well as nucleic acid sequences encoding these. The invention also relates to host cells expressing nucleic acids encoding the mannose-specific adhesins or variants thereof, as well as to pharmaceutical or nutraceutical compositions comprising the mannose-specific adhesins and/or host cells expressing the adhesins, and their use in treating or preventing bacterial infection. Further, screening methods suitable for identifying bacteria strains with probiotic properties are provided.

摘要翻译： 本发明涉及新型甘露糖特异性粘附素及其变体，以及编码这些粘附素的核酸序列。 本发明还涉及表达编码甘露糖特异性粘附素或其变体的核酸的宿主细胞，以及包含表达粘附素的甘露糖特异性粘附素和/或宿主细胞的药物或营养组合物及其在治疗或预防中的用途 细菌感染。 此外，提供了适用于鉴定具有益生菌特性的细菌菌株的筛选方法。

公开(公告)号：WO0125225A3

公开(公告)日：2001-11-01

申请号：PCT/EP0009644

申请日：2000-09-29

申请人： SHELL INT RESEARCH ,  JONG FEIKE DE ,  KREBS ACHIM ,  SNEL JOHANNES JACOBUS MARIA ,  SUYKERBUYK JACOBA CATHERINA LU ,  UYTTERHOEVEN GRIET

发明人： DE JONG FEIKE ,  KREBS ACHIM ,  SNEL JOHANNES JACOBUS MARIA ,  SUYKERBUYK JACOBA CATHERINA LU ,  UYTTERHOEVEN GRIET

IPC分类号： C07D317/18 ,  C07D317/22 ,  C08F2/08 ,  C08F20/04 ,  C08F20/28

CPC分类号： C07D317/22 ,  C07D317/18

摘要： Poly(ortho ester) intermediate of general formula (I) wherein R1, R2 and R3 are the same or different and each may represent an alkyl group containing from 1 to 10 carbon atoms and preferably from 1 to 6, wherein n represents an integer in the range of from 1 to 20 and preferably from 1 to 10; process for their preparation; adducts of glycidylesters and carboxylic acids and preferably acrylic acids, derived from said ortho esters; coating compositions comprising a binder component derived from said adducts.

摘要翻译： 通式（I）的聚（原酸酯）中间体，其中R 1，R 2和R 3相同或不同，并且各自表示含有1至10个碳原子，优选1至6的烷基，其中n表示 范围为1至20，优选1至10; 其准备过程; 衍生自所述原酸酯的缩水甘油酯和羧酸，优选丙烯酸的加合物; 涂料组合物包含衍生自所述加合物的粘合剂组分。