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公开(公告)号：WO2011046431A1
公开(公告)日：2011-04-21
申请号：PCT/NL2010/050670
申请日：2010-10-11
申请人： CAMPINA NEDERLAND HOLDING B.V. , THIESSEN-BOLDER, Suzanne Godelieve , CAO, Linqiu , TORRES, Iliana Hidalgo
CPC分类号： C07K1/34 , A21D13/80 , A23C9/1425 , A23C21/10 , A23J1/20 , A23J1/205 , A23J3/08 , A23L33/18 , A23L33/19 , A23V2002/00 , A23V2250/54252 , C07K14/47 , G01N21/78 , G01N33/04 , A23V2200/224
摘要： The invention pertains to process for manufacturing whey protein concentrate (WPC) from whey, said process involving (a) providing acidified whey; (b) increasing the pH of said acidified whey using one or more carbonate salt(s), preceded and/or followed by ultrafiltration, and (c) subjecting the ultrafϊltered carbonate-containing whey to spray drying. A WPC is provided having improved functional properties, particularly increased gel strength and reduced salt sensitivity (i.e. meaning that the functional properties of the WPC are affected by salt to a lesser extent).
摘要翻译： 本发明涉及从乳清制备乳清蛋白浓缩物（WPC）的方法，所述方法包括（a）提供酸化的乳清; （b）在超滤之前和/或之后使用一种或多种碳酸盐提高所述酸化乳清的pH值，和（c）对超滤过碳酸酯的乳清进行喷雾干燥。 提供了具有改进的功能性能，特别是增加的凝胶强度和降低的盐敏感性的WPC（即，意味着WPC的功能特性受到较小程度的盐的影响）。
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公开(公告)号：WO2009020389A1
公开(公告)日：2009-02-12
申请号：PCT/NL2008/050534
申请日：2008-08-04
CPC分类号： C12N5/0018 , C12N2500/40 , C12N2500/76
摘要： A proteolysate of a seed material derived from a plant species of the Asteraceae family, such as sunflower, has improved properties as a constituent of a culture medium for culturing eukaryotic, in particular animal cells. The seed material is defatted and is hydrolysed to a degree of 10 - 50% and subsequently separated from insolubles. The cells are particularly cultured for producing desir ed protein products.
摘要翻译： 衍生自菊科的植物物种如向日葵的种子材料的蛋白水解作为培养真核生物，特别是动物细胞的培养基的组分具有改进的性质。 种子材料脱脂并水解至10-50％的程度，随后与不溶物分离。 细胞被特别培养用于生产需要的蛋白质产物。
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3.发明申请USE OF A PROTEIN HYDROLYSATE FOR ENHANCING ACTIVITY OF GLUCAGON-LIKE PEPTIDE-1 审中-公开蛋白水解酶用于增强葡萄球菌肽-1活性的应用
公开(公告)号：WO2007064208A1
公开(公告)日：2007-06-07
申请号：PCT/NL2006/050301
申请日：2006-11-30
CPC分类号： A61K35/20
摘要： A protein hydrolysate having a degree of hydrolysis between 1 and 40% and containing between 1 and 70 wt.% of peptides having a molecular weight of less than 500 Da and less than 55 wt.% of peptides or proteins having a molecular weight of more than 5000 Da, on the basis of the total proteinaceous material of the composition, is effective in stimulating secretion of glucagon- like peptide- 1 (GLP-I). In addition, the hydrolysate may have DPP-IV inhibiting activity. The hydrolysate is suitable for the manufacture of a medicament, or food product for prophylaxis and/or treatment of a GLP-I mediated condition, in particular obesity, type 2 diabetes mellitus and an immunological disorder.
摘要翻译： 具有1至40％之间水解度并含有1至70重量％的分子量小于500Da且小于55重量％的分子量更大的肽或蛋白质的肽的蛋白质水解产物 基于组合物的总蛋白质物质的5000Da有效刺激胰高血糖素样肽-1（GLP-1）的分泌。 此外，水解产物可能具有DPP-IV抑制活性。 该水解产物适用于制备用于预防和/或治疗GLP-1介导的病症，特别是肥胖症，2型糖尿病和免疫学障碍的药物或食品。
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公开(公告)号：WO2006098625A1
公开(公告)日：2006-09-21
申请号：PCT/NL2006/050055
申请日：2006-03-14
CPC分类号： A61K35/20 , A61K9/2018 , A61K9/2059 , A61K38/40 , Y10S514/859
摘要： The invention provides a method for the treatment of acne comprising orally administering to a person suffering from acne an effective amount of a whey protein fraction containing lactoferrin, and preferably containing further specific whey proteins. The lactoferrin is preferably native bovine lactoferrin and the whey protein fraction is administered at a level of between 10 mg and 2 g lactoferrin per patient per day.
摘要翻译： 本发明提供了一种治疗痤疮的方法，包括口服给予痤疮患者有效量的含有乳铁蛋白的乳清蛋白质级分，并且优选含有其它特异性乳清蛋白。 乳铁蛋白优选为天然牛乳铁蛋白，并且乳清蛋白级分每天患者以10mg至2g乳铁蛋白的水平施用。
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公开(公告)号：WO2010019036A3
公开(公告)日：2010-02-18
申请号：PCT/NL2009/050489
申请日：2009-08-12
申请人： CAMPINA NEDERLAND HOLDING B.V. , GERRITS, Antonius Johannes Maria , VAN SCHAIJK, Rianne Maria Allegonda Hendrik
IPC分类号： C12G3/06
摘要： The invention relates to an alcoholic beverage containing between 15 and 150 g/l of a particulate nut material, wherein the nut material has a particle size, preferably bimodal,between 0.05 and 200 ?m and the beverage contains 5 between 0.2 and 1.0 wt.% of a stabiliser comprising microcrystalline cellulose and optionally a soluble and/or anionic polysaccharide such as CMC.
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6.发明申请
公开(公告)号：WO2009154447A1
公开(公告)日：2009-12-23
申请号：PCT/NL2009/050342
申请日：2009-06-15
发明人： Cao, Linqiu , Maas, Hans
CPC分类号： A61K38/40 , A23L33/19 , A23V2002/00 , A23V2250/54248 , A23V2250/606 , A23V2250/61 , A23V2250/628 , A23V2250/64 , A61K9/08 , A61K47/26
摘要： The invention pertains to an aqueous composition containing lactoferrin, 35 –70 wt% carbohydrate and/or polyol stabilizers, based on the total weight of the aqueous composition, said composition exhibiting a pH higher than 2, lower than 5. At these 5 conditions, the aqueous composition and lactoferrin contained therein may be subjected to a heat treatment without significantly affecting the physiological activity of the lactoferrin. The invention thus particularly pertains to the above aqueous composition, being heat-treated, thus containing heat-stabilized lactoferrin.
摘要翻译： 本发明涉及基于水性组合物的总重量含有乳铁蛋白，35-70重量％碳水化合物和/或多元醇稳定剂的含水组合物，所述组合物的pH高于2，低于5.在这5个条件下， 可以对其中含有的水性组合物和乳铁蛋白进行热处理，而不会显着影响乳铁蛋白的生理活性。 因此，本发明特别涉及上述水性组合物，经过热处理，因此含有热稳定的乳铁蛋白。
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公开(公告)号：WO2009014421A1
公开(公告)日：2009-01-29
申请号：PCT/NL2007/050369
申请日：2007-07-25
申请人： Campina Nederland Holding B.V. , Danisco A/S , KORCZYNSKA, Marta Zdzislawa , NOORDMAN, Wouter Herman , OUWEHAND, Arthur, Constantijn
CPC分类号： A23C9/1238 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K35/20 , A61K35/747 , C12N1/20 , C12R1/225 , C12R1/23 , C12R1/245 , A23V2200/3204 , A23V2200/332
摘要： The invention relates to the field of nutrition and medicine. Provided are compositions, bacterial strains and methods for inducing or enhancing satiety and satiation and for treating or preventing obesity, overweight and overweight related diseases.
摘要翻译： 本发明涉及营养和药物领域。 提供用于诱导或增强饱腹感和饱腹感以及用于治疗或预防肥胖，超重和超重相关疾病的组合物，细菌菌株和方法。
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公开(公告)号：WO2009011573A1
公开(公告)日：2009-01-22
申请号：PCT/NL2008/050464
申请日：2008-07-09
申请人： CAMPINA NEDERLAND HOLDING B.V. , SMULDERS, Pauline Elisabeth Antoinette , SOMERS, Marco Albertus Franciscus Johannes
CPC分类号： A23L2/66 , A23C21/08 , A23L2/60 , A23V2002/00 , A23V2250/54252 , A23V2250/5046 , A23V2250/5062 , A23V2250/612 , A23V2250/628
摘要： A heat stable nutritional beverage having a pH of 6.6 - 8.2 comprising 5 -12 % w/w whey protein is obtained by incorporating 4 -16 % w/w of at least one sugar selected from di-oligo-and polysaccharides, wherein at least one monosaccharide is other than glucose.
摘要翻译： 通过掺入4-16％w / w的至少一种选自二 - 寡糖和多糖的糖，得到具有6.6-12％的包含5-12％w / w乳清蛋白的热稳定营养饮料，其中至少 一种单糖不是葡萄糖。
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公开(公告)号：WO2006068480A3
公开(公告)日：2006-06-29
申请号：PCT/NL2005/050056
申请日：2005-11-30
IPC分类号： C12N9/48 , C07K14/47 , C12P21/06 , A61K38/01 , A61K38/05 , A61K38/06 , A61K38/07 , A61K38/08 , C07K1/12 , A61P9/02 , A61P3/10 , A61P37/00
摘要： Disclosed is a protein hydrolysate having DPP-IV inhibiting activity, the hydrolysate being enriched in peptides having a length of 2-8 amino acids comprising at least one proline residue, an isolated peptide derivable from such a protein hydrolysate, or a mixture thereof, and the use of such protein hydrolysate or isolated peptide for the manufacture of a medicament, food supplement, beverage or food product for prophylaxis and/or treatment of a DPP-IV mediated condition, in particular chosen from the group of obesity, type 2 diabetes mellitus and an immunological disorder.
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10.发明申请CYSTEINE RICH PEPTIDES FOR IMPROVING THIOL HOMEOSTASIS 审中-公开CYSTEINE RICH PEPTIDES FOR IMPROVE THIOL HOMEOSTASIS
公开(公告)号：WO2005077400A1
公开(公告)日：2005-08-25
申请号：PCT/NL2004/000106
申请日：2004-02-12
申请人： CAMPINA NEDERLAND HOLDING B.V. , SPRONG, Rijkje, Cornelia , DUDEK, Steffi , TAYLOR, Fiona, Marie
CPC分类号： A61K38/011
摘要： Described is the use of a mixture of peptides, the peptides comprising at least 6.5 %wt cysteine, for the manufacture of a medicament, supplement, beverage or food product for restoring thiol homeostasis. Furthermore, a method is described for restoring thiol homeostasis in a subject in need thereof, said method comprising administering to said subject an effective amount of a mixture of peptides, the peptides comprising at least 6.5 %wt cysteine.
摘要翻译： 描述了肽的混合物（包含至少6.5重量％半胱氨酸的肽）在制备用于恢复硫醇体内平衡的药物，补充剂，饮料或食品中的用途。 此外，描述了在有需要的受试者中恢复硫醇体内平衡的方法，所述方法包括向所述受试者施用有效量的肽混合物，所述肽包含至少6.5重量％的半胱氨酸。
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