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1.发明申请IMPROVEMENT IN THE LIGAND PROTECTION FOR MERCAPTOACETYL TRIGLYCINE 审中-公开改良MERCAPTOACETYL TRIGLYCINE的配体保护
公开(公告)号：WO2005079864A3
公开(公告)日：2006-01-19
申请号：PCT/US2005004349
申请日：2005-02-11
Applicant: MALLINCKRODT INC , BLAUWHOFF MART-JAN T , KNIGHT HECTOR H , STOCK FRIEDHELM R , VERKERK VOLCMAR
Inventor： BLAUWHOFF MART-JAN T , KNIGHT HECTOR H , STOCK FRIEDHELM R , VERKERK VOLCMAR
CPC classification number: A61K51/08 , A61K51/1282 , A61K2123/00 , C07B59/008 , C07B2200/05
Abstract: The present invention relates to a method for preparing mercaptoacetyl triglycine labeled with a radionuclide, comprising the steps of adding a radionuclide to a solution that comprises a mercaptoacetyl triglycine dimer of formula VI, a reducing agent and optionally a transfer ligand and heating the thus obtained solution. The invention relates to the mercaptoacetyl triglycine dimer and its use in the method, to a kit for performing the method and to the formulation obtained from the method.
Abstract translation: 本发明涉及一种制备用放射性核素标记的巯基乙酰甘氨酸的方法，包括以下步骤：向包含式Ⅵ的巯基乙酰三ine二聚体，还原剂和任选的转移配体的溶液中加入放射性核素，并加热所得溶液 。 本发明涉及巯基乙酰三
甘氨酸二聚体及其在该方法中的用途，用于实施该方法的试剂盒和从该方法得到的制剂。-
2.发明申请IMPROVEMENT IN THE LIGAND PROTECTION FOR MERCAPTOACETYL TRIGLYCINE 审中-公开改良MERCAPTOACETYL TRIGLYCINE的配体保护
公开(公告)号：WO2005079864A2
公开(公告)日：2005-09-01
申请号：PCT/US2005/004349
申请日：2005-02-11
Applicant: MALLINCKRODT INC. , BLAUWHOFF, Mart-Jan, T. , KNIGHT, Hector, H. , STOCK, Friedhelm, R. , VERKERK, Volcmar , LINK, Siegfried , MAIER, Volker , SIDDIQUEE, Sanaul , STIEHL, Gabriele , TOMBULT-MEYER, Thomas
Inventor： BLAUWHOFF, Mart-Jan, T. , KNIGHT, Hector, H. , STOCK, Friedhelm, R. , VERKERK, Volcmar , LINK, Siegfried , MAIER, Volker , SIDDIQUEE, Sanaul , STIEHL, Gabriele , TOMBULT-MEYER, Thomas
IPC: A61K51/00
CPC classification number: A61K51/08 , A61K51/1282 , A61K2123/00 , C07B59/008 , C07B2200/05
Abstract: The present invention relates to a method for preparing mercaptoacetyl triglycine labeled with a radionuclide, comprising the steps of adding a radionuclide to a solution that comprises a mercaptoacetyl triglycine dimer of formula VI, a reducing agent and optionally a transfer ligand and heating the thus obtained solution. The invention relates to the mercaptoacetyl triglycine dimer and its use in the method, to a kit for performing the method and to the formulation obtained from the method.
Abstract translation: 本发明涉及一种制备用放射性核素标记的巯基乙酰甘氨酸的方法，包括以下步骤：向包含式Ⅵ的巯基乙酰三ine二聚体，还原剂和任选的转移配体的溶液中加入放射性核素，并加热所得溶液 。 本发明涉及巯基乙酰三
甘氨酸二聚体及其在该方法中的用途，用于实施该方法的试剂盒和从该方法得到的制剂。
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