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公开(公告)号：WO2004104178A2
公开(公告)日：2004-12-02
申请号：PCT/US2004/015457
申请日：2004-05-15
Applicant: XY, INC. , EVANS, Kenneth, M. , GILLIGAN, Thomas, B. , SUH, Tae Kwang , COX, Todd, A.
Inventor： EVANS, Kenneth, M. , GILLIGAN, Thomas, B. , SUH, Tae Kwang , COX, Todd, A.
IPC: C12N
CPC classification number: C12Q3/00 , C12N5/0612 , G01N15/147 , G01N15/1475 , G01N33/5005 , G01N2015/149 , Y10T436/12
Abstract: A flow cytometry system (1) for sorting haploid cells, specifically irradiatable sperm cells, with an intermittingly punctuated radiation emitter (56). Embodiments include a beam manipulator (21) and even split radiation beams directed to multiple nozzles (5). Differentiation of sperm characteristics with increased resolution may efficiently allow differentiated sperm cells to be separated higher speeds and even into subpopulations having higher purity.
Abstract translation: 一种流式细胞术系统（1），用于将单倍体细胞（特别是可照射的精子细胞）与中间标记的辐射发射器（56）分离。 实施例包括光束操纵器（21）以及指向多个喷嘴（5）的均匀的分束辐射束。 精子特征与分辨率的分化可以有效地使分化精子细胞分离更高的速度，甚至可以分离出具有较高纯度的亚群。
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2.发明申请SYSTEM TO SEPARATE FROZEN-THAWED SPERMATOZOA INTO X-CHROMOSOME BEARING AND Y-CHROMOSOME BEARING POPULATIONS 审中-公开将冷冻超细粉末分离成X染色体轴承和Y染色体轴承人口的系统
公开(公告)号：WO0243574A8
公开(公告)日：2003-11-20
申请号：PCT/US0145023
申请日：2001-11-29
Applicant: XY INC , COLORADO STATE UNIVERSITY THRO , SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
Inventor： SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
CPC classification number: C12N5/0604 , A01N1/02 , A01N1/0263 , A01N1/0273 , A61D19/00
Abstract: Devices, compositions, and methods for handling, separating, packaging, and utilization of spermatozoa (1) that can be derived from previously frozen sperm sampels collected forma male mammel. Specifically, techniques to uniformily stain (2) spermatozoal DNA even when derived from previously frozen sperm and separation techniques to separate and isolate spermatozoa even when derived from previously frozen sperm samples into X-chromosome bearing and Y-chromosome bearing populations having high purity.
Abstract translation: 用于处理，分离，包装和利用精子的装置，组合物和方法（1），其可以从先前冷冻的精子血浆衍生来收集形成雄性哺乳动物。 具体来说，即使从先前冷冻的精子和分离技术得到的精子DNA均匀染色（2）精子DNA的技术，即使从先前冷冻的精子样品衍生到具有高纯度的携带X染色体的Y染色体群体中也能分离和分离精子。
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3.发明申请SYSTEM TO SEPARATE FROZEN-THAWED SPERMATOZOA INTO X-CHROMOSOME BEARING AND Y-CHROMOSOME BEARING POPULATIONS 审中-公开将冷冻超细粉末分离成X染色体轴承和Y染色体轴承人口的系统
公开(公告)号：WO0243574A3
公开(公告)日：2002-08-29
申请号：PCT/US0145023
申请日：2001-11-29
Applicant: XY INC , COLORADO STATE UNIVERSITY THRO , SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
Inventor： SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
CPC classification number: C12N5/0604 , A01N1/02 , A01N1/0263 , A01N1/0273 , A61D19/00
Abstract: Devices, compositions, and methods for handling, separating, packaging, and utilization of spermatozoa (1) that can be derived from previously frozen sperm sampels collected forma male mammel.Specifically, techniques to uniformily stain (2) spermatozoal DNA even when derived from previously frozen sperm and separation techniques to separate and isolate spermatozoa even when derived from previously frozen sperm samples into X-chromosome bearing and Y-chromosome bearing populations having high purity.
Abstract translation: 用于处理，分离，包装和利用精子的装置，组合物和方法（1），其可以从先前冷冻的精子血浆中获得，从雄性哺乳动物收集。特别地，即使从先前产生的精子DNA均匀染色（2）精子DNA的技术 冷冻精子和分离技术分离和分离精子，即使从先前冷冻的精子样品衍生到具有高纯度的携带X染色体和Y染色体的群体中。
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4.发明申请SEX SELECTED EQUINE INTRACYTOPLASMIC SPERM INJECTION EMBRYO PRODUCTION SYSTEM 审中-公开SEX选择的EQUINE INTRACYTOPLASMIC SPERM INJECTION EMBRYO生产系统
公开(公告)号：WO2009014643A1
公开(公告)日：2009-01-29
申请号：PCT/US2008/008772
申请日：2008-07-18
Applicant: XY, INC. , COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (CSURF) , SUH, Tae, Kwang , SQUIRES, Edward, L. , CARNEVALE, Elaine , GRAHAM, James, K. , MORENO, Juan, F.
Inventor： SUH, Tae, Kwang , SQUIRES, Edward, L. , CARNEVALE, Elaine , GRAHAM, James, K. , MORENO, Juan, F.
IPC: A01K31/19
CPC classification number: C12N15/873 , A01K67/027 , A01K2227/10
Abstract: Intracytoplasmic sperm injection utilizing sex-selected equine spermatozoa to obtain viable sex selected embryos transferable to a recipient female equine mammal to obtain sex selected foals.
Abstract translation: 利用性别选择的精子精子进行胞浆内精子注射，以获得可转移到受体雌性马哺乳动物以获得性别选择的驹的可行性选择的胚胎。
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Patent Agency Ranking
公开(公告)号：WO2004012837A2
公开(公告)日：2004-02-12
申请号：PCT/US2003/024460
申请日：2003-08-01
Applicant: XY, INC. , COLORADO STATE UNIVERSITY , SCHENK, John, L. , SEIDEL, George, E. , SUH, Tae, Kwang
Inventor： SCHENK, John, L. , SEIDEL, George, E. , SUH, Tae, Kwang
IPC: B01D
CPC classification number: C12N5/0612 , A01K67/027 , A01K2227/10 , A01K2227/101 , A61D19/00 , C12N5/061 , C12N2517/10 , Y10T442/2115
Abstract: A sperm cell process system providing to generate sperm cell insemination samples having controlled sperm cell fertility characteristics of sperm cells.
Abstract translation: 精子细胞过程系统提供精子细胞授精样品，其具有精子细胞的受精精子细胞生殖力特征。
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6.发明申请SYSTEM TO SEPARATE FROZEN-THAWED SPERMATOZOA INTO X-CHROMOSOME BEARING AND Y-CHROMOSOME BEARING POPULATIONS 审中-公开将冷冻精子分为X染色体和Y染色体群的系统
公开(公告)号：WO0243574A9
公开(公告)日：2003-12-18
申请号：PCT/US0145023
申请日：2001-11-29
Applicant: XY INC , COLORADO STATE UNIVERSITY THRO , SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
Inventor： SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
CPC classification number: C12N5/0604 , A01N1/02 , A01N1/0263 , A01N1/0273 , A61D19/00
Abstract: Devices, compositions, and methods for handling, separating, packaging, and utilization of spermatozoa (1) that can be derived from previously frozen sperm sampels collected forma male mammel. Specifically, techniques to uniformily stain (2) spermatozoal DNA even when derived from previously frozen sperm and separation techniques to separate and isolate spermatozoa even when derived from previously frozen sperm samples into X-chromosome bearing and Y-chromosome bearing populations having high purity.
Abstract translation: 用于处理，分离，包装和利用精子的装置，组合物和方法（1），所述精子（1）可以来自先前冷冻的精子样品，所述样品收集为雄性母体。 具体而言，即使当来自先前冷冻的精子和分离技术以分离和分离精子时，甚至当来自先前冷冻的精子样品进入具有高纯度的携带X染色体和携带Y染色体的群体时，均匀染色（2）精子DNA的技术。
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7.发明申请SYSTEM FOR IN-VITRO FERTILIZATION WITH SPERMATOZOA SEPARATED INTO X-CHROMOSOME AND Y-CHROMOSOME BEARING POPULATIONS 审中-公开用于分离为X染色体和Y染色体轴承人群的孢子的体外培养体系
公开(公告)号：WO0243486A9
公开(公告)日：2003-04-17
申请号：PCT/US0145237
申请日：2001-11-29
Applicant: XY INC , UNIV COLORADO STATE , SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
Inventor： SEIDEL GEORGE E , SUH TAE KWANG , LU KEHUAN
CPC classification number: C12N5/0604 , A01N1/02 , A01N1/0263 , A01N1/0273 , A61D19/00
Abstract: An IVF system for successfully utilizing spermatozoa separated into X-chromosome bearing and into Y-chromosome bearing population for insemination. The IVF system includes fertilization medium that can shorten the time from insemination to cleavage and a portable incubator for the transportation of maturing oocytes and inseminated oocytes comprising a straw (19) and an incubation element (20) that can be sealed with a cap (22).
Abstract translation: 用于成功利用分离为X染色体的精子和携带Y染色体的人体进行授精的IVF系统。 IVF系统包括可以缩短从授精到切割的时间的受精培养基，以及用于运输成熟的卵母细胞和授精卵母细胞的便携式培养箱，其包括可以用盖（22）密封的吸管（19）和孵育元件（20） ）。
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公开(公告)号：WO2004104178A3
公开(公告)日：2006-01-26
申请号：PCT/US2004015457
申请日：2004-05-15
Applicant: XY INC , EVANS KENNETH M , GILLIGAN THOMAS B , SUH TAE KWANG , COX TODD A
Inventor： EVANS KENNETH M , GILLIGAN THOMAS B , SUH TAE KWANG , COX TODD A
CPC classification number: C12Q3/00 , C12N5/0612 , G01N15/147 , G01N15/1475 , G01N33/5005 , G01N2015/149 , Y10T436/12
Abstract: A flow cytometry system (1) for sorting haploid cells, specifically irradiatable sperm cells, with an intermittingly punctuated radiation emitter (56). Embodiments include a beam manipulator (21) and even split radiation beams directed to multiple nozzles (5). Differentiation of sperm characteristics with increased resolution may efficiently allow differentiated sperm cells to be separated higher speeds and even into subpopulations having higher purity.
Abstract translation: 一种流式细胞术系统（1），用于将单倍体细胞（特别是可照射的精子细胞）与中间标记的辐射发射器（56）分离。 实施例包括光束操纵器（21）以及指向多个喷嘴（5）的均匀的分束辐射束。 精子特征与分辨率的分化可有效地使分化精子细胞分离更高的速度，甚至可以分离成具有较高纯度的亚群。
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公开(公告)号：WO2004012837A3
公开(公告)日：2004-08-19
申请号：PCT/US0324460
申请日：2003-08-01
Applicant: XY INC , UNIV COLORADO STATE , SCHENK JOHN L , SEIDEL GEORGE E , SUH TAE KWANG
Inventor： SCHENK JOHN L , SEIDEL GEORGE E , SUH TAE KWANG
CPC classification number: C12N5/0612 , A01K67/027 , A01K2227/10 , A01K2227/101 , A61D19/00 , C12N5/061 , C12N2517/10 , Y10T442/2115
Abstract: A sperm cell process system providing to generate sperm cell insemination samples having controlled sperm cell fertility characteristics of sperm cells.
Abstract translation: 一种精子细胞加工系统，用于生成具有精子细胞受控精子细胞繁殖特性的精子细胞授精样品。
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