利索-全球专利检索

  1. Login
  2. Sign Up

Search Results

4 records (took 0.012 seconds)

    LONIDAMINE ANALOGUES FOR FERTILITY MANAGEMENT
    2.
    发明申请
    LONIDAMINE ANALOGUES FOR FERTILITY MANAGEMENT 审中-公开
    用于肥胖管理的LONIDAMINE ANALOGUES

    公开(公告)号：WO2011005759A2

    公开(公告)日：2011-01-13

    申请号：PCT/US2010/041065

    申请日：2010-07-06

    Applicant: UNIVERSITY OF KANSAS ,  GEORGE, Ingrid, Gunda ,  TASH, Joseph, S. ,  CHAKRSALI, Ramappa ,  JAKKARAJ, Sudhakar, R. ,  CALVET, James, P.

    Inventor： GEORGE, Ingrid, Gunda ,  TASH, Joseph, S. ,  CHAKRSALI, Ramappa ,  JAKKARAJ, Sudhakar, R. ,  CALVET, James, P.

    IPC: C07D231/56 ,  C07D471/04 ,  A61K31/416 ,  A61K31/4162 ,  A61P15/00

    CPC classification number: C07D471/04 ,  A61K31/416 ,  A61K31/4162 ,  C07D231/56

    Abstract: Fertility management can include: administering to the subject one or more doses of a compound according to Formula I so as to reduce fertility in the subject. Fertility management can also include administering an effective amount of the compound to: impair Sertoli cell function in a male subject; inhibit spermatogenesis in the subject; reduce testis weight in the subject; reduce ovary weight in a female subject; reduce serum progesterone in the female subject; impair ovarian follicle function in the female subject; causing reversible fertility in the subject. In order to return fertility, the method can include ceasing administration of the compound to the subject so as to return fertility in the subject. The compound can be administered for irreversibly sterilizing the subject.

    Abstract translation: 生育能力管理可以包括：向受试者施用一种或多种剂量的式I化合物，以降低受试者的生育能力。 生育能力管理还可以包括给予有效量的化合物以损害男性受试者的Sertoli细胞功能; 抑制受试者的精子发生; 减少受试者的睾丸重量; 减少女性受试者的卵巢重量; 减少女性受试者的血清孕酮; 影响女性卵巢卵泡功能; 导致受试者的可逆生育力。 为了返回生育力，该方法可以包括停止对受试者施用化合物以使受试者的生育力恢复。 该化合物可被用于不可逆地灭菌受试者。

    LONIDAMINE ANALOGUES FOR FERTILITY MANAGEMENT
    3.
    发明申请
    LONIDAMINE ANALOGUES FOR FERTILITY MANAGEMENT 审中-公开
    洛美林类似物的肥育管理

    公开(公告)号：WO2011005759A3

    公开(公告)日：2011-05-12

    申请号：PCT/US2010041065

    申请日：2010-07-06

    Applicant: UNIV KANSAS ,  GEORGE INGRID GUNDA ,  TASH JOSEPH S ,  CHAKRSALI RAMAPPA ,  JAKKARAJ SUDHAKAR R ,  CALVET JAMES P

    Inventor： GEORGE INGRID GUNDA ,  TASH JOSEPH S ,  CHAKRSALI RAMAPPA ,  JAKKARAJ SUDHAKAR R ,  CALVET JAMES P

    IPC: C07D231/56 ,  A61K31/416 ,  A61K31/4162 ,  A61P15/00 ,  C07D471/04

    CPC classification number: C07D471/04 ,  A61K31/416 ,  A61K31/4162 ,  C07D231/56

    Abstract: Fertility management can include: administering to the subject one or more doses of a compound according to Formula I so as to reduce fertility in the subject. Fertility management can also include administering an effective amount of the compound to: impair Sertoli cell function in a male subject; inhibit spermatogenesis in the subject; reduce testis weight in the subject; reduce ovary weight in a female subject; reduce serum progesterone in the female subject; impair ovarian follicle function in the female subject; causing reversible fertility in the subject. In order to return fertility, the method can include ceasing administration of the compound to the subject so as to return fertility in the subject. The compound can be administered for irreversibly sterilizing the subject.

    Abstract translation: 生育管理可以包括：给受试者施用一个或多个剂量的式I化合物以降低受试者的生育力。 生育管理还可以包括施用有效量的化合物以：损害男性受试者的支持细胞功能; 抑制受试者的精子发生; 减少受试者的睾丸重量; 减少女性受试者的卵巢重量; 减少女性受试者的血清孕酮; 损害女性受试者的卵泡功能; 导致受试者可逆的生育力。 为了恢复生育能力，该方法可以包括停止向受试者施用化合物以便恢复受试者的生育力。 该化合物可以被施用以不可逆地消毒受试者。

Patent Agency Ranking