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公开(公告)号:WO2022136063A1
公开(公告)日:2022-06-30
申请号:PCT/EP2021/085962
申请日:2021-12-15
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: WALSH, John
Abstract: Structural tubing assemblies and methods of assembling them are disclosed. The structural tubing assembly (100) comprises a first tubular member (101) having a male connection portion (110) configured with one or more projections (112); a second tubular member (102) having a female connection portion (120) configured to receive the one or more projections of the male connection portion in an assembled configuration; and a fastening means (130) configured to releasably secure the male connection portion (110) to the female connection portion (120) in the assembled configuration. The fastening means (130) comprises an end-piece (131) configured to engage an end of the second tubular member, and a threaded fastener (132) configured to extend through an opening (137) in the end-piece and engage with at least one of the one or more projections of the male connection portion, and/or with the aid of an insert (133) with a threaded hole.
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2.
公开(公告)号:WO2021123455A2
公开(公告)日:2021-06-24
申请号:PCT/EP2020/087546
申请日:2020-12-21
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: FLITCROFT, Ian , LOUGHMAN, James
Abstract: A computer implemented system and method for determining and analysing ocular refractive error of an eye. The method determines a set of sample biometric factors for a reference sample of eyes from a set of reference sample physical characteristics. Physical characteristics of a patient's eye are measured such that the type of measured patient physical characteristics include some or all of the reference sample characteristic types. Patient biometric factors are then calculated based on the measured and inherent patient physical characteristics and compared with the sample biometric factors to determine the effect of one or more parameters on the ocular refractive error of an eye. The method may calculate the difference between the refractive contribution of the axial length, cornea and internal optics in the patient's eye and the separate contribution from those factors in the sample physical characteristics.
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3.
公开(公告)号:WO2020128632A2
公开(公告)日:2020-06-25
申请号:PCT/IB2019/001412
申请日:2019-12-21
Applicant: CRANNMED LIMITED , TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: FARRISSEY, Liam , DUFFY, Brendan , AGARWAL, Sankalp
Abstract: A method for coating an inner lumen surface of a tube with a coating solution comprises the steps of moving a coating solution through a tube via a withdrawal system and depositing the coating solution onto an inner lumen surface of the tube. The thickness of the coating solution is deposited onto the inner lumen surface of the tube is between 1 μm and 25 μm. The method further comprises applying a pressure to the tube using a pressure source when the coating solution is within the tube to manipulate a surface tension between the coating solution and the inner lumen surface of the tube.
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公开(公告)号:WO2020053451A3
公开(公告)日:2020-03-19
申请号:PCT/EP2019/074754
申请日:2019-09-16
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: KNOX, Andrew
IPC: G16B15/30 , B01D15/08 , B01J20/281 , C07K1/22
Abstract: There is provided a method of identifying a resin for isolating or enriching a protein of interest using affinity chromatography. The method comprises the steps of: i) providing the three-dimensional structure of the protein of interest; ii) determining and/or calculating one or more parameters of the protein of interest in its two- and/or three-dimensional form; iii) determining and/or calculating one or more parameters of one or more resin in their two- and/or three-dimensional form; and iv) selecting a resin expected to bind complementarily to the protein of interest based upon one or more of the parameters of the protein of interest.
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公开(公告)号:WO2022112589A1
公开(公告)日:2022-06-02
申请号:PCT/EP2021/083517
申请日:2021-11-30
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: COOKE, Gordon , CARAHER, Emma , BRADY, Jonathan
IPC: A61K31/202 , A61K31/7048 , A61P31/04
Abstract: Provided is DHA, or a composition comprising DHA, for use in treatment of a biofilm in a subject and for use in treatment of a disease or infection associated or caused by a biofilm in a subject.
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公开(公告)号:WO2021116355A1
公开(公告)日:2021-06-17
申请号:PCT/EP2020/085645
申请日:2020-12-10
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: MICLOS, Michelle
Abstract: A process for producing a synthetic tear drop suitable for forming a liquid contact lens film, comprising the steps of providing a drop of liquid comprising a lipid phase, an aqueous phase, and optionally a mucous phase, and a meniscus between the lipid phase and the aqueous phase, and treating the drop by electrowetting to change the shape of meniscus and provide a modified tear drop suitable for forming a liquid contact lens. Also disclosed is a synthetic tear drop having a lipid phase comprising oil, an aqueous phase comprising water, electrolytes, surfactant such as an amino acid and optionally metabolites, optionally a mucous phase containing mucins, and a meniscus between the lipid phase and the aqueous phase, wherein the shape of the aqueous phase has been modified by electrowetting. The modified tear drop is generally compositionally and volumetrically similar to a natural human basal tear.
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7.
公开(公告)号:WO2020128632A3
公开(公告)日:2020-06-25
申请号:PCT/IB2019/001412
申请日:2019-12-21
Applicant: CRANNMED LIMITED , TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: FARRISSEY, Liam , DUFFY, Brendan , AGARWAL, Sankalp
Abstract: A method for coating an inner lumen surface of a tube with a coating solution comprises the steps of moving a coating solution through a tube via a withdrawal system and depositing the coating solution onto an inner lumen surface of the tube. The thickness of the coating solution is deposited onto the inner lumen surface of the tube is between 1 μm and 25 μm. The method further comprises applying a pressure to the tube using a pressure source when the coating solution is within the tube to manipulate a surface tension between the coating solution and the inner lumen surface of the tube.
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公开(公告)号:WO2020127795A1
公开(公告)日:2020-06-25
申请号:PCT/EP2019/086398
申请日:2019-12-19
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: MEADE, Aidan , QUIGLEY, Frances Eileen , AMARANDEI, George
IPC: G01N21/21
Abstract: We describe a method and a system for analysing a sample (12) using spectral polarimetry. The system comprises a light source, a first polarizer (22) having a first polarization angle for polarizing light from the light source, a second polarizer having a second polarization angle which is different to the first polarization angle, a birefringent component (20) which comprises a birefringent material, and a detector for receiving polarized light from the second polarizer (16). The birefringent component is positioned between the first and second polarizers and the sample is placed between the first polarizer and the second polarizer. The method comprises directing polarized light having a first polarization angle through a birefringent component which comprises a birefringent material, illuminating the sample with the light passing through the birefringent component, directing light through a polarizer having a second polarization angle which is different to the first polarization angle, and detecting the light transmitted through the polarizer.
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公开(公告)号:WO2023083917A1
公开(公告)日:2023-05-19
申请号:PCT/EP2022/081369
申请日:2022-11-09
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: MURPHY, Niall , COX, Stephen
IPC: A61F9/06
Abstract: Disclosed is a welding shield that includes an air supply conduit for receiving and supplying ambient air into an internal portion of the welding shield, a sensor provided within the air supply conduit at an inlet of the conduit for detecting presence of one or more harmful gases in the ambient air, before the ambient air reaches the wearer for inhaling, and an alerting system operably coupled to the sensor for alerting the wearer upon detection of the one or more harmful gases in the ambient air.
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公开(公告)号:WO2022136667A1
公开(公告)日:2022-06-30
申请号:PCT/EP2021/087559
申请日:2021-12-23
Applicant: TECHNOLOGICAL UNIVERSITY DUBLIN
Inventor: AGARWARL, Sankalp
IPC: A61K33/00 , A61L31/06 , A61L31/12 , A61L31/14 , A61P19/08 , A61L27/44 , A61L27/46 , A61L27/50 , A61L27/54 , A61L27/58
Abstract: This invention relates to a guided bone regeneration membrane that can be used to seal bone defects and prevent the invasion of surrounding soft connective tissue without obstructing the exchange of the surrounding body fluids.
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