公开(公告)号：WO2011033473A1

公开(公告)日：2011-03-24

申请号：PCT/IB2010/054197

申请日：2010-09-16

Applicant: RANBAXY LABORATORIES LIMITED ,  MUKHTAR, Sayeed ,  NAIR, Dinesh, Shashidharan ,  MEDHANE, Roshan, Ramesh ,  MAHESHWARI, Nitin ,  MEERAN, Hashim, Nizar, Poovanathil, Nagoor ,  TEWARI, Neera ,  PRASAD, Mohan

Inventor： MUKHTAR, Sayeed ,  NAIR, Dinesh, Shashidharan ,  MEDHANE, Roshan, Ramesh ,  MAHESHWARI, Nitin ,  TEWARI, Neera ,  PRASAD, Mohan

IPC: C07C209/70 ,  C07C211/30

CPC classification number: C07C209/68 ,  C07C17/16 ,  C07C29/58 ,  C07C209/08 ,  C07C209/70 ,  C07C211/30 ,  C07C33/483

Abstract: The present invention provides processes and intermediates for preparing cinacalcet base and pharmaceutically acceptable salts thereof.

Abstract translation: 本发明提供了制备西那卡塞碱及其药学上可接受的盐的方法和中间体。

公开(公告)号：WO2007029084A3

公开(公告)日：2007-03-15

申请号：PCT/IB2006/002416

申请日：2006-09-01

Applicant: RANBAXY LABORATORIES LIMITED ,  TEWARI, Neera ,  GEORGE, Vinod ,  MANE, Avinash, Sheshrao ,  MEERAN, Hashim, Nizar, Poovanathil, Nagoor ,  PRASAD, Mohan

Inventor： TEWARI, Neera ,  GEORGE, Vinod ,  MANE, Avinash, Sheshrao ,  MEERAN, Hashim, Nizar, Poovanathil, Nagoor ,  PRASAD, Mohan

IPC: C07D477/20

Abstract: The present invention relates to a an improved process for the preparation of carbapenem compounds involving the deprotection of a compound of Formula (IV) to form a thiol of Formula (I) which is then further condensed with a compound of Formula (III).

公开(公告)号：WO2006035300A2

公开(公告)日：2006-04-06

申请号：PCT/IB2005002889

申请日：2005-09-28

Applicant: RANBAXY LAB LTD ,  MANE AVINASH SHESHRAO ,  TEWARI NEERA ,  MEERAN HASHIM NIZAR POOVANATHI ,  RAI BISHWA PRAKASH ,  KUMAR YATENDRA

Inventor： TEWARI NEERA ,  MEERAN HASHIM NIZAR POOVANATHI ,  RAI BISHWA PRAKASH ,  KUMAR YATENDRA

IPC: C07D477/20

CPC classification number: C07D477/20

Abstract: The present invention provides a one-pot process for the preparation of meropenem. The present invention further provides a process for the preparation of meropenem trihydrate.

Abstract translation: 本发明提供了用于制备美罗培南的一锅法。 本发明还提供了用于制备美罗培南三水合物的方法。

公开(公告)号：WO2005021560A1

公开(公告)日：2005-03-10

申请号：PCT/IB2004/002777

申请日：2004-08-27

Applicant: RANBAXY LABORATORIES LIMITED ,  KUMAR, Yatendra ,  TEWARI, Neera ,  RAI, Bishwa, Prakash

Inventor： KUMAR, Yatendra ,  TEWARI, Neera ,  RAI, Bishwa, Prakash

IPC: C07F7/18

CPC classification number: C07F7/188 ,  Y02A50/39

Abstract: The present invention relates to a process for the preparation of esters of 2-diazo-3-trimethylsilyloxy-3-butenoic acid which comprises reacting a diazoacetoacetate with iodotrimethylsilane in the presence of an organic base, wherein iodotrimethylsilane is prepared by reacting hexamethyldisilane with iodine. The present invention further relates to converting such esters of 2-diazo-3-trimethylsilyloxy-3-butenoic acid to other compounds, such as a substituted diazoazetidinone, an azetidinone, or a bicyclo ketoester.

Abstract translation: 本发明涉及2-重氮-3-三甲基甲硅烷氧基-3-丁烯酸的酯的制备方法，其包括在有机碱的存在下使重氮乙酰乙酸与碘代三甲基硅烷反应，其中碘代三甲基硅烷通过六甲基二硅烷与碘反应制备。 本发明还涉及将2-重氮-3-三甲基甲硅烷氧基-3-丁烯酸的酯转化为其它化合物，例如取代的重氮基吖丁酮，氮杂环丁酮或双环酮酯。

公开(公告)号：WO2004110399A3

公开(公告)日：2005-02-17

申请号：PCT/IB2004002040

申请日：2004-06-18

Applicant: RANBAXY LAB LTD ,  KUMAR YATENDRA ,  TEWARI NEERA ,  SINGH SHAILENDRA KUMAR ,  RAI BISHWA PRAKASH

Inventor： KUMAR YATENDRA ,  TEWARI NEERA ,  SINGH SHAILENDRA KUMAR ,  RAI BISHWA PRAKASH

IPC: A61K31/545 ,  C07D501/00

CPC classification number: A61K31/545

Abstract: The invention relates to N-methylpyrrolidone and N,N-dimethylacetamide solvates of cefprozil. The invention also relates to processes for preparing the solvates of cefprozil, crystalline cefprozil from said solvates and pharmaceutical compositions that include the crystalline cefprozil.

Abstract translation: 本发明涉及头孢丙烯的N-甲基吡咯烷酮和N，N-二甲基乙酰胺溶剂合物。 本发明还涉及从所述溶剂合物制备头孢丙烯溶剂合物，结晶头孢普the的溶剂化物的方法和包括结晶头孢普and的药物组合物。

公开(公告)号：WO2011132172A1

公开(公告)日：2011-10-27

申请号：PCT/IB2011/051757

申请日：2011-04-21

Applicant: RANBAXY LABORATORIES LIMITED ,  PANDYA, Vishwesh, Pravinchandra ,  RICHHARIYA, Santosh ,  DIVYA, Prabhakar ,  MEERAN, Hashim, Nizar, Poovanathil, Nagoor ,  TEWARI, Neera

Inventor： PANDYA, Vishwesh, Pravinchandra ,  RICHHARIYA, Santosh ,  DIVYA, Prabhakar ,  MEERAN, Hashim, Nizar, Poovanathil, Nagoor ,  TEWARI, Neera

IPC: C07D417/12 ,  A61K31/505 ,  A61P3/00

CPC classification number: C07D417/12 ,  C07D239/26

Abstract: The present invention provides a process for preparing novel intermediates of Formula wherein, R 1 can be hydrogen, C 1 -C 4 alkyl, halogen, nitro, hydroxy, or C 1 -C 4 alkoxy; R x can be selected from hydrophobic residue of HMG-CoA reductase inhibitors; which can be effectively used for the preparation of HMG-CoA reductase inhibitors such as rosuvastatin and pharmaceutically acceptable salts thereof.

Abstract translation: 本发明提供一种制备新型中间体的方法，其中R 1可以是氢，C 1 -C 4烷基，卤素，硝基，羟基或C 1 -C 4烷氧基; Rx可以选自HMG-CoA还原酶抑制剂的疏水残基; 其可以有效地用于HMG-CoA还原酶抑制剂如罗苏伐他汀及其药学上可接受的盐的制备。

公开(公告)号：WO2010089729A1

公开(公告)日：2010-08-12

申请号：PCT/IB2010/050596

申请日：2010-02-09

Applicant: RANBAXY LABORATORIES LIMITED ,  TEWARI, Neera ,  MOHAMMAD, Kallimulla ,  RAI, Bishwa, Prakash ,  HUSSAIN, Mashkoor

Inventor： TEWARI, Neera ,  MOHAMMAD, Kallimulla ,  RAI, Bishwa, Prakash ,  HUSSAIN, Mashkoor

IPC: C07D501/46 ,  A61K31/546

CPC classification number: C07D519/06

Abstract: The present invention relates to processes for the preparation of cefozopran of Formula (I), its salts and polymorphic forms thereof.

Abstract translation: 本发明涉及制备式（I）的塞夫唑啉及其盐和多晶型的方法。

公开(公告)号：WO2009069012A1

公开(公告)日：2009-06-04

申请号：PCT/IB2008/051691

申请日：2008-04-30

Applicant: RANBAXY LABORATORIES LIMITED ,  NAIR, Dinesh, Shashidharan ,  RAI, Bishwa, Prakash ,  MEERAN, Hashim, Nizar, Poovanathil, Nagoor ,  TEWARI, Neera

Inventor： NAIR, Dinesh, Shashidharan ,  RAI, Bishwa, Prakash ,  MEERAN, Hashim, Nizar, Poovanathil, Nagoor ,  TEWARI, Neera

IPC: C07F9/655 ,  A61K31/506 ,  C07D411/04 ,  A61P31/18

CPC classification number: C07F9/65515 ,  C07D411/04

Abstract: The present invention relates to process and intermediates for the preparation of substituted 1,3-oxathiolanes. The present invention specifically relates to a process for the preparation of lamivudine.

Abstract translation: 本发明涉及制备取代的1,3-氧硫杂环戊烷的方法和中间体。 本发明具体涉及制备拉米夫定的方法。

公开(公告)号：WO2004110399A2

公开(公告)日：2004-12-23

申请号：PCT/IB2004/002040

申请日：2004-06-18

Applicant: RANBAXY LABORATORIES LIMITED ,  KUMAR, Yatendra ,  TEWARI, Neera ,  SINGH, Shailendra, Kumar ,  RAI, Bishwa, Prakash

Inventor： KUMAR, Yatendra ,  TEWARI, Neera ,  SINGH, Shailendra, Kumar ,  RAI, Bishwa, Prakash

IPC: A61K9/00

CPC classification number: A61K31/545

Abstract: The invention relates to solvates of cefprozil. The invention also relates to processes for preparing the solvates of cefprozil, crystalline cefprozil from said solvates and pharmaceutical compositions that include the crystalline cefprozil.

Abstract translation: 本发明涉及头孢丙烯的溶剂合物。 本发明还涉及从所述溶剂合物制备头孢丙烯溶剂合物，结晶头孢普the的溶剂化物的方法和包括结晶头孢普and的药物组合物。

公开(公告)号：WO02094773A2

公开(公告)日：2002-11-28

申请号：PCT/IB0201718

申请日：2002-05-20

Applicant: RANBAXY LAB LTD ,  KUMAR YATENDRA ,  TEWARI NEERA ,  ARYAN RAM CHANDER ,  RAI BISHWA PRAKASH

Inventor： KUMAR YATENDRA ,  TEWARI NEERA ,  ARYAN RAM CHANDER ,  RAI BISHWA PRAKASH

IPC: C07D477/00 ,  C07D477/02 ,  C07D477/20 ,  C30B7/04 ,  C30B29/54 ,  C07D

CPC classification number: C07D477/20 ,  C07D477/02

Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity.

Abstract translation: 本发明涉及用于制备高纯度亚胺培南的成本有效和工业上有利的方法。