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公开(公告)号:WO2004001785A2
公开(公告)日:2003-12-31
申请号:PCT/GB2003/002634
申请日:2003-06-19
Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE , ROSE, Mervyn, John , SILVA, Ravi , SHANNON, John , HAJTO, Janos, Peter
Inventor: ROSE, Mervyn, John , SILVA, Ravi , SHANNON, John , HAJTO, Janos, Peter
IPC: H01J9/00
CPC classification number: H01J1/3044 , G02F2001/133625 , H01J2201/30407 , H01J2201/30446 , H01L51/5225
Abstract: There is disclosed an improved field emission device (30) which finds use in display devices, such as a flat panel displays. Known devices and displays suffer from problems such as complexity of fabrication and limited colour gamut. The device (30) therefore provides a field emission backplate (38) which is made from a substantially semiconductor based material and comprises a plurality of grown tips (32), the device (30) further comprising at least one electro-luminescent and/or photo-luminescent material (34) having a fluorescent material chemically attached thereto, i.e. a fluorescent dye doped material.
Abstract translation: 公开了一种可用于诸如平板显示器的显示装置中的改进的场致发射装置(30)。 已知的装置和显示器存在制造复杂性和色域有限等问题。 因此,装置(30)提供由基本上半导体的材料制成并包括多个生长的尖端(32)的场发射背板(38),所述装置(30)还包括至少一个电致发光和/或 具有与其化学连接的荧光材料的光致发光材料(34),即荧光染料掺杂材料。
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公开(公告)号:WO2003091266A3
公开(公告)日:2003-11-06
申请号:PCT/GB2003/001721
申请日:2003-04-23
Inventor: QUINLAN, Roy
IPC: C07K19/00
Abstract: The present invention relates to protein chaperones, such as hybrid chaperones and methods for stabilising proteins and protein activities comprising adding said protein chaperone to the protein. The present invention also provides a stabilised protein formulation comprising said protein chaperone associated with a protein and further relates to the enhancement of native chaperone activity by making hybrid protein chaperones.
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公开(公告)号:WO2003091266A2
公开(公告)日:2003-11-06
申请号:PCT/GB2003/001721
申请日:2003-04-23
Inventor: QUINLAN, Roy
IPC: C07H
CPC classification number: C07K14/47 , A61K38/00 , C07K1/1133 , C07K2319/00
Abstract: The present invention relates to protein chaperones, such as hybrid chaperones and methods for stabilising proteins and protein activities comprising adding said protein chaperone to the protein. The present invention also provides a stabilised protein formulation comprising said protein chaperone associated with a protein and further relates to the enhancement of native chaperone activity by making hybrid protein chaperones.
Abstract translation: 本发明涉及蛋白质分子伴侣,例如杂交伴侣和用于稳定蛋白质和蛋白质活性的方法,包括向蛋白质中加入所述蛋白质分子伴侣。 本发明还提供了包含与蛋白质相关的所述蛋白质分子伴侣的稳定化蛋白质制剂,并且还涉及通过制备杂交蛋白伴侣蛋白来增强天然伴侣活性。
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公开(公告)号:WO2002095417A2
公开(公告)日:2002-11-28
申请号:PCT/GB2002/002393
申请日:2002-05-20
Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE , LAMOND, Angus, Iain , MUNYA, Paul, Ajuh
Inventor: LAMOND, Angus, Iain , MUNYA, Paul, Ajuh
IPC: G01N33/68
CPC classification number: G01N33/6875 , G01N2500/02
Abstract: The present invention relates to a method for screening agents which modulate the binding of CDC5L to PLRG1, or specified fragments thereof, and agents identified using such an assay. The present invention also provides small peptides capable of inhibiting pre-mRNA splicing. Such agents are candidates for use in the treatment of , for example, cancer, or fungal infections.
Abstract translation: 本发明涉及一种筛选调节CDC5L与PLRG1或其特定片段的结合的筛选方法以及使用这种测定鉴定的试剂。 本发明还提供能够抑制mRNA前体剪接的小肽。 这些试剂是用于治疗例如癌症或真菌感染的候选物。
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公开(公告)号:WO2002082653A2
公开(公告)日:2002-10-17
申请号:PCT/GB2002/001407
申请日:2002-03-27
Inventor: PARKES, Stephen, Maxwell
IPC: H03K19/177
CPC classification number: H03K19/17736 , H03K19/17784
Abstract: There is disclosed an improved integrated circuit (5) and a related system apparatus and method. The integrated circuit (5) comprises: a plurality of logic area of user logic areas (10); and an actively switchable network capable of selectively connecting at least one logic area (10) is with another logic area (10).
Abstract translation: 公开了一种改进的集成电路(5)和相关的系统装置和方法。 集成电路(5)包括:用户逻辑区域(10)的多个逻辑区域; 并且能够选择性地连接至少一个逻辑区域(10)的主动切换网络与另一逻辑区域(10)相连。
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公开(公告)号:WO2002062399A1
公开(公告)日:2002-08-15
申请号:PCT/GB2002/000528
申请日:2002-02-07
Inventor: MEIER-AUGENSTEIN, Wolfram
IPC: A61K51/12
CPC classification number: A61K51/1206 , A61K51/1296
Abstract: The present invention relates to the provision of a stable solid food product, comprising carbohydrate, protein, fat, fibre and 13 C acetic acid or salt thereof, which is suitable for use in gastric emptying tests; as well as a method for preparing the food product; and conducting a gastric emptying test utilising the food product.
Abstract translation: 本发明涉及提供稳定的固体食品,其包含碳水化合物,蛋白质,脂肪,纤维和13 C乙酸或其盐,其适用于胃排空试验; 以及制备食品的方法; 并进行利用食品的胃排空试验。
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公开(公告)号:WO1997042909A1
公开(公告)日:1997-11-20
申请号:PCT/GB1997001282
申请日:1997-05-13
Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE , PITTS, Nigel, Berry , LONGBOTTOM, Christopher , LOS, Przemyslaw
IPC: A61C19/04
CPC classification number: A61C19/04 , A61B5/053 , A61B5/4547
Abstract: An apparatus for the electronic detection of dental caries comprises at least one probe electrode (10) placed in electrical contact with the surface of a patient's tooth, and a second electrode (12) placed in electrical contact with another part of the body of the patient; an alternating electrical current is passed between the probe (10) and the second electrode (12). The frequency of the alternating current is varied over a predetermined frequency range and the electrical impedance between the electrodes (10, 12) is measured for a number of frequency values within the range. A variety of probe designs to suit different types of teeth and different tooth surfaces generally comprise an insulating substrate (120) of hydrophobic material, such as Goretex, and one or more electrodes (122), preferably of a conductive, hydrophobic material such as carbon-impregnated Goretex.
Abstract translation: 用于电子检测龋齿的装置包括放置成与患者牙齿的表面电接触的至少一个探针电极(10)和与患者的身体的另一部分电接触放置的第二电极(12) ; 在探针(10)和第二电极(12)之间通过交流电流。 交变电流的频率在预定频率范围内变化,并且在该范围内测量多个频率值之间的电极(10,12)之间的电阻抗。 适合不同类型的齿和不同齿表面的各种探针设计通常包括疏水材料的绝缘衬底(120),例如Goretex,以及一个或多个电极(122),优选为导电的疏水材料,例如碳 浸渍的Goretex。
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公开(公告)号:WO1997023635A1
公开(公告)日:1997-07-03
申请号:PCT/GB1996003212
申请日:1996-12-23
Applicant: THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE , ROSLIN INSTITUTE (EDINBURGH) , CLARK, Anthony, John , WOLF, Charles, Roland
IPC: C12N15/85
CPC classification number: A01K67/0275 , A01K2217/05 , C12N9/0071 , C12N15/85 , C12N2830/001 , C12N2830/85
Abstract: The present invention relates to a recombinant genetic material which can be operably linked to protein encoding sequence comprising an expression control sequence having at least one promoter region and at least one repressor region such that basal expression in a tissue where the protein is required to be expressed is reduced whilst allowing induction of expression of the protein encoding sequence. Suitably the promoter is a p450 type promoter whilst suitably it is the p450 CYP1A1 promoter of the rat. The invention further provides a method of manufacturing proteins for polypeptides in the method of manufacturing or recombinant construct for transgene induction.
Abstract translation: 本发明涉及重组遗传物质,其可以与包含具有至少一个启动子区域和至少一个阻遏物区域的表达控制序列的蛋白质编码序列可操作地连接,使得需要表达蛋白质的组织中的基础表达 同时允许诱导蛋白质编码序列的表达。 合适地,启动子是p450型启动子,而合适地是大鼠的p450 CYP1A1启动子。 本发明进一步提供了在制造方法中制造多肽的蛋白质的方法或用于转基因诱导的重组构建体。
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公开(公告)号:WO1994011787A1
公开(公告)日:1994-05-26
申请号:PCT/GB1993002391
申请日:1993-11-19
IPC: G03F07/004
CPC classification number: H01L21/283 , C07F1/00 , C23C16/18 , G03F1/76 , G03F7/0042 , G03F7/16 , G03F7/2043
Abstract: There is described a method of chemically depositing a substance. The method is of utility in the direct manufacture of integrated circuits and in the manufacture of a photomask for use in production of integrated circuits. The method involves the use of a compound which degrades into a deposit and a residue when a radiant beam (e.g. a laser beam) or a particle beam (e.g. an electron beam) is applied. The residue and any unreacted compound may be washed off the substrate to which it has been applied. Nanoscale dimensions of the deposit can be achieved. A particularly suitable organometallic compound is tetra-sec butyl diaurum difluoride.
Abstract translation: 描述了一种化学沉积物质的方法。 该方法在集成电路的直接制造和用于集成电路生产中的光掩模的制造中是有用的。 当施加辐射束(例如激光束)或粒子束(例如电子束)时,该方法包括使用降解成沉积物的化合物和残余物。 残余物和任何未反应的化合物可以从其已经被施用的基材上洗去。 可以实现沉积物的纳米级尺寸。 特别合适的有机金属化合物是四仲丁基二氟化二氟。
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公开(公告)号:WO1991004067A1
公开(公告)日:1991-04-04
申请号:PCT/GB1990001465
申请日:1990-09-21
IPC: A61M16/00
CPC classification number: G01N33/0016 , G01N33/0011
Abstract: Apparatus for monitoring gas from a ventilator is described in which a sensor is provided in a sensing chamber (103) which is in gaseous communication with a gas supply conduit (102) which supplies gas from the ventilator to a patient. The gaseous communication (11) between the chamber (103) and the conduit (102) enables gas from the conduit (102) to enter the sensing chamber (103) and subsequently to re-enter the conduit (102). Typically, a baffle (15) is provided to divert a portion of the gas in conduit (102) into the chamber (103) and a heater coil (107) may also be provided to ensure that the temperature of the gas in the vicinity of the sensor is above the dewpoint of the gas.
Abstract translation: 描述了用于监测来自呼吸机的气体的装置,其中传感器设置在感测室(103)中,所述感测室与气体供应管道(102)气态连通,所述气体供应管道从呼吸机向患者提供气体。 腔室(103)和导管(102)之间的气体连通(11)使得来自导管(102)的气体能够进入感测室(103)并随后重新进入导管(102)。 通常,提供挡板(15)以将导管(102)中的气体的一部分转移到腔室(103)中,并且还可以设置加热器线圈(107),以确保气体在 传感器高于气体露点。
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