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    TREATMENT OF INFLAMMATORY AND/OR BACTERIAL CONDITIONS WITH PARTICLES OF MICROSTRUCTURE
    1.
    发明申请
    TREATMENT OF INFLAMMATORY AND/OR BACTERIAL CONDITIONS WITH PARTICLES OF MICROSTRUCTURE 审中-公开
    用微观结构的颗粒处理炎症和/或细菌条件

    公开(公告)号：WO2008103082A1

    公开(公告)日：2008-08-28

    申请号：PCT/SE2007/000985

    申请日：2007-11-06

    Applicant: TIGRAN TECHNOLOGIES AB (PUBL) ,  BJURSTEN, Lars, Magnus ,  MJÖBERG, Bengt

    Inventor： BJURSTEN, Lars, Magnus ,  MJÖBERG, Bengt

    IPC: A61L27/54 ,  A61P29/00 ,  A61L27/06

    CPC classification number: A61L27/06 ,  A61K9/0019 ,  A61K9/0063 ,  A61K9/1611 ,  A61K9/501 ,  A61L27/56

    Abstract: The present invention refers to a method for treatment of an inflamma- tory and/or bacterial condition, wherein particles of microstructure comprising titanium, titanium alloy, at least one titanium oxide or a combination thereof, and having a surface with at least a substantial part consisting of at least one type of titanium oxide, are brought into contact with at least one infected site in a human or animal body by insertion, injection or implantation, which at least one infected site exhibits the inflammatory and/or bacterial condition. Moreover, the present invention refers to an injectable suspension comprising the particles according to the invention and a fluid vehicle for use as a medicament. Finally, the present invention also defines use of the particles of microstructure according to the invention for the manufacture of a medicament in the form of an injectable suspension. Examples of conditions being treated with the injectable suspension according to the present invention are periodontitis, periimplantitis, and osteitis.

    Abstract translation: 本发明涉及一种用于治疗炎症和/或细菌病症的方法，其中包括钛，钛合金，至少一种氧化钛或其组合的微结构微粒，并且具有至少大部分的表面 由至少一种类型的氧化钛通过插入，注射或植入与人或动物体内的至少一个感染部位接触，至少一个感染部位显示出炎症和/或细菌状况。 此外，本发明涉及包含根据本发明的颗粒和用作药物的流体载体的可注射悬浮液。 最后，本发明还定义了根据本发明的微结构颗粒用于制造可注射悬浮液形式的药物的用途。 用根据本发明的可注射悬浮液治疗的病症的实例是牙周炎，周围炎和骨炎。

    POROUS TITANIUM OR TITANIUM ALLOY BLOCK
    3.
    发明申请
    POROUS TITANIUM OR TITANIUM ALLOY BLOCK 审中-公开
    多孔钛或钛合金块

    公开(公告)号：WO2011075066A1

    公开(公告)日：2011-06-23

    申请号：PCT/SE2010/051400

    申请日：2010-12-16

    Applicant: TIGRAN TECHNOLOGIES AB (PUBL) ,  BJURSTEN, Lars Magnus ,  MJÖBERG, Bengt

    Inventor： BJURSTEN, Lars Magnus ,  MJÖBERG, Bengt

    IPC: A61L27/56 ,  A61L27/06 ,  A61L27/30

    CPC classification number: A61L27/06 ,  A61C8/0015 ,  A61L27/30 ,  A61L27/34 ,  A61L27/56

    Abstract: The present invention provides a porous block for implantation in the maxillofacial area of a human or animal, wherein the porous block: -comprises titanium metal and/or a titanium alloy; -has a porosity of at least 40%; -is a geometrical structure shaped to fit at least a part of a degraded alveolar process of the human or animal; and -has an intended bone contacting surface intended to be in contact with the bone surface of an implantation site in the maxillofacial area of the human or animal, wherein said bone contacting surface has pores extending through the porous block and wherein at least some of these pores have a pore diameter size of at least 50 µm to ensure bone ingrowth; and wherein -the porous block is a geometrical structure having a width, a height and a length, said intended bone contacting surface being defined by the width and the length, wherein the average value of the width is in the range of 5-10 mm, the average value of the height is in the range of 3-10 mm and the average value of the length is in the range of 5-100 mm.

    Abstract translation: 本发明提供一种用于植入人或动物颌面的多孔块，其中所述多孔块： - 包括钛金属和/或钛合金; - 孔隙率至少为40％; - 形状为适合人或动物的降解的肺泡过程的至少一部分的几何结构; 并且具有旨在与人或动物的颌面区域中的植入部位的骨表面接触的预期骨接触表面，其中所述骨接触表面具有延伸穿过多孔块的孔，并且其中至少一些 毛孔具有至少50μm的孔径尺寸以确保骨向内生长; 并且其中所述多孔块是具有宽度，高度和长度的几何结构，所述预期骨接触表面由宽度和长度限定，其中所述宽度的平均值在5-10mm的范围内 高度的平均值在3-10mm的范围内，长度的平均值在5-100mm的范围内。

    POROUS IMPLANT GRAIN OR GRANULE
    4.
    发明申请
    POROUS IMPLANT GRAIN OR GRANULE 审中-公开
    多孔植物颗粒或颗粒

    公开(公告)号：WO2008103081A1

    公开(公告)日：2008-08-28

    申请号：PCT/SE2007/000984

    申请日：2007-11-06

    Applicant: TIGRAN TECHNOLOGIES AB (PUBL) ,  BJURSTEN, Lars Magnus ,  MJÖBERG, Bengt ,  AXÉN, Niklas

    Inventor： BJURSTEN, Lars Magnus ,  MJÖBERG, Bengt ,  AXÉN, Niklas

    IPC: A61L27/54 ,  A61P29/00 ,  A61L27/06

    CPC classification number: A61L27/06 ,  A61F2/28 ,  A61F2002/3092 ,  A61F2310/00023 ,  A61F2310/00616 ,  A61K9/0024 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/412

    Abstract: The present invention is related to an implant with anti-inflammatory or antibacterial effects, or both, the implant being intended for implantation in a human or an animal body, the implant comprising at least one porous granule or grain, wherein the at least one porous granule or grain comprises titanium, one or more titanium oxides or titanium alloy and has a titanium oxide layer on its surface; has a mean length from one side to the opposite side, through a geometrical centre, of up to 5 mm; has a mean specific surface area of at least 0.15 m 2 /g according to the BET method. Moreover, disclosed is also a method for treating a condition comprising an inflammation or/and an infection present in a human or animal body with implants according to the invention. Described is also a method for producing implants according to the invention.

    Abstract translation: 本发明涉及一种植入物，其具有抗炎或抗菌效果，或两者都涉及用于植入人或动物体内的植入物，所述植入物包含至少一种多孔颗粒或颗粒，其中所述至少一种多孔 颗粒或颗粒包括钛，一种或多种钛氧化物或钛合金，并且在其表面上具有氧化钛层; 具有从一侧到另一侧的平均长度，通过几何中心至多5mm; 根据BET法，平均比表面积至少为0.15m 2 / g。 此外，还公开了一种用于根据本发明用植入物治疗包含存在于人或动物体内的炎症或/和感染的病症的方法。 还描述了根据本发明的用于生产植入物的方法。

    WHITENING OF METALS
    5.
    发明申请
    WHITENING OF METALS 审中-公开
    金属白色

    公开(公告)号：WO2016182500A1

    公开(公告)日：2016-11-17

    申请号：PCT/SE2016/050428

    申请日：2016-05-12

    Applicant: TIGRAN TECHNOLOGIES AB (PUBL)

    Inventor： BJURSTEN, Lars-Magnus ,  AXÉN, Niklas

    IPC: A61C8/00 ,  A61C13/00 ,  C23C8/10 ,  C23C28/04 ,  C25D11/24

    CPC classification number: A61C8/00 ,  A61C8/0013 ,  A61C8/0015 ,  A61C13/00 ,  C23C8/02 ,  C23C8/10 ,  C23C8/36 ,  C23C8/80 ,  C25D11/24 ,  C25D11/26

    Abstract: The present invention relates to a method for the production of a whitened surface of an object comprising a metal or a metal alloy. The present invention further relates to an object having a whitened surface, wherein the whitened surface has been produced according to the present invention. The invention also relates to a whitened implantable unit having a whitened surface. The implantable unit may be an implantable dental unit.

    Abstract translation: 本发明涉及一种用于生产包含金属或金属合金的物体的增白表面的方法。 本发明还涉及具有发白表面的物体，其中已经根据本发明生产了增白表面。 本发明还涉及具有白化表面的增白植入单元。 可植入单元可以是可植入牙科单元。

    DENTAL IMPLANT UNIT
    7.
    发明申请
    DENTAL IMPLANT UNIT 审中-公开
    牙齿植入单元

    公开(公告)号：WO2014104966A1

    公开(公告)日：2014-07-03

    申请号：PCT/SE2013/051593

    申请日：2013-12-20

    Applicant: TIGRAN TECHNOLOGIES AB (PUBL)

    Inventor： BJURSTEN, Lars Magnus ,  NILSSON, Sven-Erik ,  AXÉN, Niklas ,  HILBORN, Jöns Gunnar

    IPC: A61C8/00 ,  A61C13/00

    CPC classification number: A61C5/77 ,  A61C8/0006 ,  A61C8/0015 ,  A61C8/005 ,  A61C13/0006 ,  A61C13/082 ,  A61K6/0023 ,  A61K6/04 ,  A61K33/38 ,  A61L27/06 ,  A61L27/54 ,  A61L2300/104 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/412 ,  A61L2300/414 ,  F04C2270/0421 ,  Y10T29/49568

    Abstract: The present invention describes a dental implant unit comprising titanium, wherein the dental implant unit has at least one surface (end) for connection and a lateral surface covering all of the implant unit but the connecting end and wherein the lateral surface comprises a layer of synthetically created titanium dioxide and wherein at least the end for connection is free from synthetically created titanium dioxide. Furthermore, the present invention is related to both full-body implants, such as screws, abutments, implant parts, bridges or crowns, and smaller implant bodies, such as particles, grains or granules. In the latter case, the present invention is directed to a whitened implantable dental unit, said dental unit comprising titanium in the form of a titanium metal or titanium alloy, and/or in the form of titanium oxide, said dental unit having a surface comprising synthetically created titanium dioxide and which surface also comprises fluoride bound to the surface. Moreover, the present invention is also related to a method for the production of a whitened implantable dental unit, said method comprising thermal oxidation of a dental implant unit comprising titanium and being solid or porous in the presence of fluoride ions, for the production of a whitened implantable dental unit having a surface comprising synthetically created titanium dioxide.

    Abstract translation: 本发明描述了一种包括钛的牙科植入物单元，其中牙科植入物单元具有用于连接的至少一个表面（端部）和覆盖所有植入单元但是连接端的侧表面，并且其中侧表面包括合成层 产生二氧化钛，并且其中至少连接端不含合成产生的二氧化钛。 此外，本发明涉及全身植入物，例如螺钉，基台，植入部件，桥或牙冠，以及较小的植入物体，例如颗粒，颗粒或颗粒。 在后一种情况下，本发明涉及增白的可植入牙科单元，所述牙科单元包括钛金属或钛合金形式的钛和/或氧化钛形式，所述牙科单元具有包括 合成产生的二氧化钛，并且该表面还包含与表面结合的氟化物。 此外，本发明还涉及一种用于生产增白的可植入牙科单元的方法，所述方法包括在氟化物离子存在下包含钛并且为固体或多孔的牙科植入物单元的热氧化，用于生产 美白的可植入牙科单元具有包括合成产生的二氧化钛的表面。

    PARTICLES, GRAINS OR GRANULES FOR THE TREATMENT OF AN INJURED VERTEBRA
    9.
    发明申请
    PARTICLES, GRAINS OR GRANULES FOR THE TREATMENT OF AN INJURED VERTEBRA 审中-公开
    用于治疗受伤VERTEBRA的颗粒，颗粒或颗粒

    公开(公告)号：WO2009061251A1

    公开(公告)日：2009-05-14

    申请号：PCT/SE2008/000629

    申请日：2008-11-05

    Applicant: TIGRAN TECHNOLOGIES AB (PUBL) ,  BJURSTEN, Lars, Magnus ,  MJÖBERG, Bengt

    Inventor： BJURSTEN, Lars, Magnus ,  MJÖBERG, Bengt

    IPC: A61L27/56 ,  A61L27/06 ,  A61F2/28 ,  A61F2/44

    CPC classification number: A61B17/7095 ,  A61F2/44 ,  A61L27/06 ,  A61L27/56 ,  Y10T428/2982

    Abstract: The present invention provides a method for treatment of a condition comprising at least one weakened vertebra or one compression fracture of a vertebra, wherein the vertebra is injected by vertebroplasty or kyphoplasty with particles, grains or granules or a mixture thereof, or an implant suspension comprising at least one resorbable fluid vehicle and particles, grains or granules or a mixture thereof, wherein the particles, grains or granules individually have a mean length from one side to the opposite side, through a geometrical centre, of up to 5 mm. Moreover, the present invention also provides use of the particular or granular material disclosed above, for the manufacture of a medicament for the vertebroplastic treatment or kyphoplastic treatment of a condition compri- sing at least one weakened vertebra or one compression fracture of a vertebra. Finally, the present invention provides the particular or granular material disclosed above, for the vertebroplastic treatment or kyphoplastic treatment of a condition comprising at least one weakened vertebra or one compression fracture of a vertebra, such as a condition like osteoporosis.

    Abstract translation: 本发明提供一种用于治疗包括椎骨的至少一个削弱的椎骨或一个椎骨的压缩性骨折的病症的方法，其中所述椎骨通过椎体成形术或椎体后凸成形术注射颗粒，颗粒或颗粒或其混合物，或植入物悬浮液，其包含 至少一种可再吸收的流体载体和颗粒，颗粒或颗粒或其混合物，其中颗粒，颗粒或颗粒各自具有从一侧到相对侧的平均长度，通过几何中心至多5mm。 此外，本发明还提供了上述公开的特定或颗粒状材料的用途，用于制造用于椎骨治疗或脊柱后凸治疗的药物，所述药物包括至少一个弱化的椎骨或椎骨的一个压缩性骨折。 最后，本发明提供了上述公开的特定或颗粒状材料，用于椎骨治疗或脊柱后凸治疗包括椎骨的至少一个削弱的椎骨或一个压缩性骨折（例如骨质疏松症）的病症。

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