公开(公告)号：WO2009110523A3

公开(公告)日：2009-12-10

申请号：PCT/JP2009054107

申请日：2009-02-26

Applicant: UNIV KYOTO ,  CANON KK ,  YOSHIMURA KIMIHIRO ,  TSUZUKI HIDETOSHI ,  YANO TETSUYA ,  TOMIDA YOSHINORI ,  ITO SHINZABURO ,  NITAHARA SATOSHI ,  AOKI HIROYUKI

Inventor： YOSHIMURA KIMIHIRO ,  TSUZUKI HIDETOSHI ,  YANO TETSUYA ,  TOMIDA YOSHINORI ,  ITO SHINZABURO ,  NITAHARA SATOSHI ,  AOKI HIROYUKI

IPC: A61K49/10 ,  C08F10/00 ,  C08G69/00

CPC classification number: C08G83/003 ,  A61K49/124 ,  C08G73/028 ,  C08L101/04

Abstract: Provided is a dendrimer particle having a unit that contains a fluorine atom at a plurality of branch ends of an aliphatic branched polymer (dendrimer). Further, the dendrimer particle is produced using an atom transfer radical polymerization method or the like. Thus, an F-MRI contrast medium, dendrimer particles with high contrast sensitivity and a rigorously controlled size and a method of manufacturing the same are provided.

Abstract translation: 本发明提供具有在脂肪族支化聚合物（树枝状大分子）的多个分支末端含有氟原子的单元的树枝状大分子粒子。 此外，树枝状聚合物粒子使用原子转移自由基聚合法等来制造。 因此，提供了具有高对比敏感度和严格控制尺寸的F-MRI造影剂，树枝状大分子颗粒及其制造方法。

公开(公告)号：WO2009069833A1

公开(公告)日：2009-06-04

申请号：PCT/JP2008/072113

申请日：2008-11-28

Applicant: KYOTO UNIVERSITY ,  CANON KABUSHIKI KAISHA ,  KONDO, Teruyuki ,  TSUJITA, Hiroshi ,  SIDDIQUE, Zainul, Abedin ,  MATSUKI, Shingo ,  MIURA, Hiroki ,  TOCHIO, Hidehito ,  MATSUDA, Tetsuya ,  NARAZAKI, Michiko ,  TSUZUKI, Hidetoshi ,  KUGE, Katsuaki ,  TOMIDA, Yoshinori ,  YOSHIMURA, Kimihiro ,  YANO, Tetsuya

Inventor： KONDO, Teruyuki ,  TSUJITA, Hiroshi ,  SIDDIQUE, Zainul, Abedin ,  MATSUKI, Shingo ,  MIURA, Hiroki ,  TOCHIO, Hidehito ,  MATSUDA, Tetsuya ,  NARAZAKI, Michiko ,  TSUZUKI, Hidetoshi ,  KUGE, Katsuaki ,  TOMIDA, Yoshinori ,  YOSHIMURA, Kimihiro ,  YANO, Tetsuya

IPC: C07D255/02 ,  C07D257/02 ,  C07D259/00 ,  C07D405/14 ,  A61K49/06 ,  A61K49/10

CPC classification number: C07F5/003 ,  A61K49/106 ,  C07D255/02 ,  C07D257/02 ,  C07D259/00 ,  C07D405/14

Abstract: A core of a cyclic structure represented by (-N-(CH 2 )n-) k is bonded to a dendrimer-type side chain with a specific branched structure at all nitrogen atoms in the core to produce a compound with a specific structure for producing a metal complex that exhibits a T1-reducing effect, and the resulting compound is coordinated to a metal ion that has a T1-reducing effect to obtain a metal complex that exhibits an excellent T1-reducing effect which is useful as an effective component of an MRI contrast agent and an MRI contrast agent using the same.

Abstract translation: 由（-N-（CH 2）n - ）k表示的环状结构的核心与核心中所有氮原子上具有特定支化结构的树枝状大分子侧链结合，生成具有特定结构的化合物， 具有T1还原效果的金属络合物，所得化合物与具有T1还原效果的金属离子配位，得到显示出优异的T1还原效果的金属络合物，其可用作有机组分 MRI造影剂和使用其的MRI造影剂。

公开(公告)号：WO2005086254A1

公开(公告)日：2005-09-15

申请号：PCT/JP2005/004586

申请日：2005-03-09

Applicant: CANON KABUSHIKI KAISHA ,  MIURA, Daisuke ,  NAKAYAMA, Tomonari ,  OHNISHI, Toshinobu ,  KUBOTA, Makoto ,  MASUMOTO, Akane ,  TSUZUKI, Hidetoshi ,  MIYACHI, Makiko

Inventor： MIURA, Daisuke ,  NAKAYAMA, Tomonari ,  OHNISHI, Toshinobu ,  KUBOTA, Makoto ,  MASUMOTO, Akane ,  TSUZUKI, Hidetoshi ,  MIYACHI, Makiko

IPC: H01L51/00

CPC classification number: H01L51/0512 ,  H01L51/0012 ,  H01L51/0077 ,  H01L51/0078 ,  H01L51/0533 ,  H01L51/0545

Abstract: There is provided a field effect transistor having an organic semiconductor layer, including: an organic semiconductor layer containing at least porphyrin; and a layer composed of at least a polysiloxane compound, the layer being laminated on the organic semiconductor layer so as to be in intimate contact with the organic semiconductor layer. As a result, there can be provided a field effect transistor which enables an organic semiconductor layer having high crystallinity and high orientation to be formed and which exhibits a high mobility.

Abstract translation: 提供了具有有机半导体层的场效应晶体管，包括：至少含有卟啉的有机半导体层; 以及由至少聚硅氧烷化合物构成的层，该层层叠在有机半导体层上以与有机半导体层紧密接触。 结果，可以提供能够形成具有高结晶度和高取向性的有机半导体层并具有高迁移率的场效应晶体管。

公开(公告)号：WO2009110523A2

公开(公告)日：2009-09-11

申请号：PCT/JP2009/054107

申请日：2009-02-26

Applicant: KYOTO UNIVERSITY ,  CANON KABUSHIKI KAISHA ,  YOSHIMURA, Kimihiro ,  TSUZUKI, Hidetoshi ,  YANO, Tetsuya ,  TOMIDA, Yoshinori ,  ITO, Shinzaburo ,  NITAHARA, Satoshi ,  AOKI, Hiroyuki

Inventor： YOSHIMURA, Kimihiro ,  TSUZUKI, Hidetoshi ,  YANO, Tetsuya ,  TOMIDA, Yoshinori ,  ITO, Shinzaburo ,  NITAHARA, Satoshi ,  AOKI, Hiroyuki

IPC: A61K49/10 ,  C08G69/00 ,  C08F10/00

CPC classification number: C08G83/003 ,  A61K49/124 ,  C08G73/028 ,  C08L101/04

Abstract: Provided is a dendrimer particle having a unit that contains a fluorine atom at a plurality of branch ends of an aliphatic branched polymer (dendrimer). Further, the dendrimer particle is produced using an atom transfer radical polymerization method or the like. Thus, an F-MRI contrast medium, dendrimer particles with high contrast sensitivity and a rigorously controlled size and a method of manufacturing the same are provided.

Abstract translation: 提供了在脂肪族支链聚合物（树枝状大分子）的多个分支端具有含有氟原子的单元的树枝状大分子粒子。 此外，使用原子转移自由基聚合法等制造树枝状大分子粒子。 因此，提供了F-MRI造影剂，具有高对比度灵敏度的树枝状大分子颗粒和严格控制的尺寸及其制造方法。