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1.发明申请IDENTIFICATION OF SURFACE-ASSOCIATED ANTIGENS FOR TUMOR DIAGNOSIS AND THERAPY 审中-公开表层相关抗原的肿瘤的诊断和治疗的识别
公开(公告)号：WO2006100089A2
公开(公告)日：2006-09-28
申请号：PCT/EP2006002695
申请日：2006-03-23
Applicant: GANYMED PHARMACEUTICALS AG , SAHIN UGUR , TUERECI OEZLEM , KOSLOWSKI MICHAEL , HELFTENBEIN GERD , USENER DIRK , SCHLUETER VOLKER
Inventor： SAHIN UGUR , TUERECI OEZLEM , KOSLOWSKI MICHAEL , HELFTENBEIN GERD , USENER DIRK , SCHLUETER VOLKER
CPC classification number: G01N33/57492 , C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , G06F19/22
Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
Abstract translation: 根据肿瘤相关基因产物和编码它们的核酸已经确定。 本发明涉及一种其中这些肿瘤相关基因产物异常表达的疾病的治疗和诊断。 此外，本发明涉及表达肿瘤相关和核酸编码它们的蛋白质，多肽和肽。
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2.发明申请IDENTIFIZIERUNG VON OBERFLÄCHEN-ASSOZIIERTEN ANTIGENEN FÜR DIE TUMORDIAGNOSE UND -THERAPIE 审中-公开表层相关抗原的肿瘤的诊断和治疗的识别
公开(公告)号：WO2005110338A2
公开(公告)日：2005-11-24
申请号：PCT/EP2005/005104
申请日：2005-05-11
Applicant: GANYMED PHARMACEUTICALS AG , TÜRECI, Özlem , SAHIN, Ugur , SCHNEIDER, Sandra , HELFTENBEIN, Gerd , SCHLÜTER, Volker , USENER, Dirk , THIEL, Philippe
Inventor： TÜRECI, Özlem , SAHIN, Ugur , SCHNEIDER, Sandra , HELFTENBEIN, Gerd , SCHLÜTER, Volker , USENER, Dirk , THIEL, Philippe
IPC: A61K
CPC classification number: A61K39/39558 , A61K39/395 , A61K45/06 , C07K14/4748 , C07K16/28 , C07K16/30 , C12Q1/6886 , C12Q2600/106 , C12Q2600/156 , G01N33/53
Abstract: Erfindungsgemäß wurden Tumor-assoziiert exprimierte Genprodukte und die daifür kodierenden Nukleinsäuren identifiziert. Die vorliegende Erfindung betrifft die Therapie und Diagnose von Erkrankungen, bei denen diese Tumor-assoziiert exprimierten Genprodukte aberrant exprimiert werden. Des weiteren betrifft die Erfindung Proteine, Polypeptide und Peptide, die Tumor-assoziiert exprimiert werden und die dafür kodierenden Nukleinsäuren.
Abstract translation: 根据本发明，鉴定了表达肿瘤相关基因产物和daifür编码核酸。 本发明涉及一种其中这些肿瘤相关的基因产物被表达异常表达的疾病的治疗和诊断。 此外，本发明涉及表达肿瘤相关和核酸编码它们的蛋白质，多肽和肽。
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公开(公告)号：WO0238803A3
公开(公告)日：2003-07-17
申请号：PCT/DE0104229
申请日：2001-11-08
Applicant: DEUTSCHES KREBSFORSCH , EICHMUELLER STEFAN , SCHADENDORF DIRK , USENER DIRK
Inventor： EICHMUELLER STEFAN , SCHADENDORF DIRK , USENER DIRK
CPC classification number: C12Q1/6886 , C12Q2600/158
Abstract: The invention relates to a novel marker for tumours, preferably CTCL. The invention further relates to the application of the above for the diagnosis and therapy of tumour-related diseases, preferably CTCL.
Abstract translation: 本发明涉及新的标志物的肿瘤，优选CTCL。 本发明还涉及它们用于肿瘤疾病，优选CTCL的诊断或治疗中的用途。
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4.发明申请
公开(公告)号：WO2008145338A3
公开(公告)日：2009-02-12
申请号：PCT/EP2008004197
申请日：2008-05-27
Applicant: GANYMED PHARMACEUTICALS AG , UNIV MAINZ JOHANNES GUTENBERG , SAHIN UGUR , TUERECI OEZLEM , BRANDENBURG GUNDA , USENER DIRK
Inventor： SAHIN UGUR , TUERECI OEZLEM , BRANDENBURG GUNDA , USENER DIRK
IPC: C07K16/30 , A61K39/395 , A61K47/48 , A61P35/00 , C12N5/12
CPC classification number: C07K16/28 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/34 , C07K2317/73 , C07K2317/732 , C07K2317/734
Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDl 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, cancer of the gallbladder, and the metastases thereof.
Abstract translation: 本发明提供了可用作治疗和/或预防与表达CLD18的细胞相关疾病的治疗剂的抗体，包括肿瘤相关疾病如胃癌，食管癌，胰腺癌，肺癌，卵巢癌，结肠癌，肝癌， 头颈癌，胆囊癌及其转移灶。
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公开(公告)号：WO2007031222A3
公开(公告)日：2007-03-22
申请号：PCT/EP2006/008695
申请日：2006-09-06
Applicant: GANYMED PHARMACEUTICALS AG , JOHANNES GUTENBERG-UNIVERSITÄT MAINZ, VERTRETEN DURCH DEN PRÄSIDENTEN , SAHIN, Ugur , TÜRECI, Özlem , KOSLOWSKI, Michael , USENER, Dirk
Inventor： SAHIN, Ugur , TÜRECI, Özlem , KOSLOWSKI, Michael , USENER, Dirk
Abstract: The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
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Patent Agency Ranking6.发明申请
公开(公告)号：WO2006100089A3
公开(公告)日：2006-09-28
申请号：PCT/EP2006/002695
申请日：2006-03-23
Applicant: GANYMED PHARMACEUTICALS AG , SAHIN, Ugur , TÜRECI, Özlem , KOSLOWSKI, Michael , HELFTENBEIN, Gerd , USENER, Dirk , SCHLÜTER, Volker
Inventor： SAHIN, Ugur , TÜRECI, Özlem , KOSLOWSKI, Michael , HELFTENBEIN, Gerd , USENER, Dirk , SCHLÜTER, Volker
Abstract: Erfindungsgemäß wurden Tumor-assoziierte Genprodukte und die dafür kodierenden Nukleinsäuren identifiziert. Die vorliegende Erfindung betrifft die Therapie und Diagnose von Erkrankungen, bei denen diese Tumor-assoziierten Genprodukte aberrant exprimiert werden. Des weiteren betrifft die Erfindung Proteine, Polypeptide und Peptide, die Tumor-assoziiert exprimiert werden und die dafür kodierenden Nukleinsäuren.
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7.发明申请
公开(公告)号：WO2008145338A2
公开(公告)日：2008-12-04
申请号：PCT/EP2008/004197
申请日：2008-05-27
Applicant: GANYMED PHARMACEUTICALS AG , JOHANNES GUTENBERG-UNIVERSITÄT MAINZ , SAHIN, Ugur , TÜRECI, Özlem , BRANDENBURG, Gunda , USENER, Dirk
Inventor： SAHIN, Ugur , TÜRECI, Özlem , BRANDENBURG, Gunda , USENER, Dirk
IPC: C07K16/30 , A61K39/395 , A61P35/00 , C12N5/12 , A61K47/48
CPC classification number: C07K16/28 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/34 , C07K2317/73 , C07K2317/732 , C07K2317/734
Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDl 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, cancer of the gallbladder, and the metastases thereof.
Abstract translation: 本发明提供了可用作治疗和/或预防与表达CLD18的细胞相关疾病的治疗剂的抗体，包括肿瘤相关疾病如胃癌，食管癌，胰腺癌，肺癌，卵巢癌，结肠癌，肝癌， 头颈癌，胆囊癌及其转移灶。
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8.发明申请
公开(公告)号：WO2007059997A1
公开(公告)日：2007-05-31
申请号：PCT/EP2006/011302
申请日：2006-11-24
Applicant: GANYMED PHARMACEUTICALS AG , JOHANNES GUTENBERG-UNIVERSITÄT MAINZ, VERTRETEN DURCH DEN PRÄSIDENTEN , SAHIN, Ugur , TÜRECI, Özlem , USENER, Dirk , FRITZ, Stefan , UHEREK, Cristoph , BRANDENBURG, Gunda , GEPPERT, Harald-Gerhard , SCHRÖDER, Anja, Kristina , THIEL, Philippe
Inventor： SAHIN, Ugur , TÜRECI, Özlem , USENER, Dirk , FRITZ, Stefan , UHEREK, Cristoph , BRANDENBURG, Gunda , GEPPERT, Harald-Gerhard , SCHRÖDER, Anja, Kristina , THIEL, Philippe
IPC: C07K16/30 , A61K39/395 , A61P35/00 , C12N5/12 , A61K47/48
CPC classification number: C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6807 , A61K47/6809 , A61K47/6813 , A61K47/6821 , A61K47/6823 , A61K47/6829 , A61K47/6851 , A61K47/6859 , A61K47/6863 , A61K47/6869 , A61K51/1063 , A61K2039/505 , C07K16/28 , C07K16/3046 , C07K2317/14 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76
Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDl 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
Abstract translation: 本发明提供了可用作治疗和/或预防与表达CLD18的细胞相关疾病的治疗剂的抗体，包括肿瘤相关疾病如胃癌，食管癌，胰腺癌，肺癌，卵巢癌，结肠癌，肝癌， 头颈癌，胆囊癌。
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9.发明申请
公开(公告)号：WO2007031222A2
公开(公告)日：2007-03-22
申请号：PCT/EP2006008695
申请日：2006-09-06
Applicant: GANYMED PHARMACEUTICALS AG , JOHANNES GUTENBERG UNI MAINZ V , SAHIN UGUR , TUERECI OEZLEM , KOSLOWSKI MICHAEL , USENER DIRK
Inventor： SAHIN UGUR , TUERECI OEZLEM , KOSLOWSKI MICHAEL , USENER DIRK
CPC classification number: A61K39/0011 , A61K45/06 , A61K2039/5256 , A61K2039/54 , A61K2039/57 , A61K2039/572 , C07K14/4748 , C07K16/2803 , C07K16/30 , C07K2317/34 , C12Q1/6886 , C12Q2600/158 , G01N33/574
Abstract: The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
Abstract translation: 本发明涉及其表达与癌症疾病相关的遗传产物。 本发明还涉及遗传产物表达或异常表达，特别是癌症疾病的疾病的治疗和诊断。
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10.发明申请IDENTIFICATION OF SURFACE-ASSOCIATED ANTIGENS FOR TUMOR DIAGNOSIS AND THERAPY 审中-公开表层相关抗原的肿瘤的诊断和治疗的识别
公开(公告)号：WO2005110338A3
公开(公告)日：2006-06-29
申请号：PCT/EP2005005104
申请日：2005-05-11
Applicant: GANYMED PHARMACEUTICALS AG , TUERECI OEZLEM , SAHIN UGUR , SCHNEIDER SANDRA , HELFTENBEIN GERD , SCHLUETER VOLKER , USENER DIRK , THIEL PHILIPPE
Inventor： TUERECI OEZLEM , SAHIN UGUR , SCHNEIDER SANDRA , HELFTENBEIN GERD , SCHLUETER VOLKER , USENER DIRK , THIEL PHILIPPE
IPC: C12Q1/68 , A61K20060101 , A61K38/17 , A61K39/395 , A61K48/00 , C07H21/00 , C07K14/705 , C07K16/30 , C12N15/12
CPC classification number: A61K39/39558 , A61K39/395 , A61K45/06 , C07K14/4748 , C07K16/28 , C07K16/30 , C12Q1/6886 , C12Q2600/106 , C12Q2600/156 , G01N33/53
Abstract: The invention relates to the identification of gene products that are the result of tumor-associated expression and the nucleic acids encoding the same. The invention also relates to the therapy and diagnosis of diseases wherein these gene products are the result of an aberrant tumor-associated expression. The invention also relates to the proteins, polypeptides and peptides that are the result of tumor-associated expression and to the nucleic acids encoding the same.
Abstract translation: 根据本发明，鉴定了表达肿瘤相关基因产物和daifür编码核酸。 本发明涉及一种其中这些肿瘤相关的基因产物被表达异常表达的疾病的治疗和诊断。 此外，本发明涉及表达肿瘤相关和核酸编码它们的蛋白质，多肽和肽。
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