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    IMPROVEMENTS IN VALVES FOR PRESSURISED DISPENSING CONTAINERS
    1.
    发明申请
    IMPROVEMENTS IN VALVES FOR PRESSURISED DISPENSING CONTAINERS 审中-公开
    用于加压分配容器的阀门的改进

    公开(公告)号：WO2002087997A1

    公开(公告)日：2002-11-07

    申请号：PCT/GB2002/001773

    申请日：2002-04-17

    Applicant: BESPAK PLC ,  WARBY, Richard, John ,  HOWLET, David

    Inventor： WARBY, Richard, John ,  HOWLET, David

    IPC: B65D83/14

    CPC classification number: B65D83/54

    Abstract: A valve for use with a pressurised dispensing container (30) containing a liquid (31), the valve comprising a slidable valve stem (11), the valve stem comprising an inlet port (24) for conveyance, in use, of liquid from the pressurised dispensing container into the valve stem, and a flange (26) against which acts a biasing means (25) which biases the valve stem into a non-dispensing position, wherein an external opening of the inlet port is located within the flange.

    Abstract translation: 一种用于与包含液体（31）的加压分配容器（30）一起使用的阀，所述阀包括可滑动的阀杆（11），所述阀杆包括入口端口（24），用于在使用中输送来自所述液体 压力分配容器进入阀杆，以及法兰（26），其上施加偏压装置（25），偏压装置（25）将阀杆偏压到非分配位置，其中入口端口的外部开口位于凸缘内。

    IMPROVEMENTS IN DRUG DELIVERY DEVICES
    2.
    发明申请
    IMPROVEMENTS IN DRUG DELIVERY DEVICES 审中-公开
    药物递送装置的改进

    公开(公告)号：WO0012163A3

    公开(公告)日：2001-05-10

    申请号：PCT/GB9901961

    申请日：1999-06-22

    Applicant: BESPAK PLC ,  BARNES PAUL ,  LECHNER MARC ,  WARBY RICHARD JOHN

    Inventor： BARNES PAUL ,  LECHNER MARC ,  WARBY RICHARD JOHN

    IPC: A61M15/00 ,  B65D83/14 ,  C08L65/04

    CPC classification number: B65D83/54 ,  A61M15/009 ,  C08L65/04

    Abstract: The invention relates to improvements to drugs delivery devices, in particular, those for dispensing a metered dose of medicament. There is provided apparatus (10, 110) for dispensing a medicament wherein at least a portion of one or more of the surfaces of components of the apparatus which come into contact with the medicament during storage or dispensing has a layer of a poly-para-xylylene polymer also known as parylene bonded to at least a portion thereof.

    Abstract translation: 本发明涉及药物递送装置的改进，特别是用于分配计量剂量的药物的改进。 提供了用于分配药物的设备（10,110），其中在储存或分配期间与药物接触的设备的部件的一个或多个部件的至少一部分表面具有多层对 - 苯二甲酰聚合物也称为对二甲苯结合到其至少一部分。

    DISPENSING DEVICE
    4.
    发明申请
    DISPENSING DEVICE 审中-公开
    分配装置

    公开(公告)号：WO1991016992A1

    公开(公告)日：1991-11-14

    申请号：PCT/GB1991000676

    申请日：1991-04-29

    Applicant: BESPAK PLC ,  BRACE, Geoffrey ,  WARBY, Richard, John

    Inventor： BESPAK PLC

    IPC: B05B11/00

    CPC classification number: B05B11/3074 ,  B05B11/3001 ,  B05B11/3039

    Abstract: A dispensing device is described in the form of a pump (10) for dispensing fluids in spray form. The device has a first piston (11) sliding in a first cylinder (15) and a second piston (12) of smaller cross-sectional area sliding in a second cylinder (16), the cylinders being in fluid communication. An inlet (31, 47) to the cylinders is provided and fluid is dispensed through an outlet (24, 25) extending through the first piston and to an outlet nozzle. A valve (28) normally closes the outlet. Springs (22, 29, 45) are provided urging the components of the device into their rest position. A metering chamber of fixed volume is formed by the second piston and cylinder, the second piston moving between limit positions defined by an abutment at the upper end of cylinder (16) and a discontinuity in the wall of the cylinder.

    Abstract translation: 公开了一种用于分配雾化形式的流体的泵分配装置（10）。 该装置具有安装成在第一气缸（15）中滑动的第一活塞（11）和安装成在第二气缸（16）中滑动的第二活塞（12），其截面具有较小的面积，所述气缸 彼此流体连通。 所述汽缸具有入口（31,47），并且所述流体经由延伸穿过所述第一活塞的出口（24,25）输送至出口喷嘴 。 通常，阀（28）关闭出口端口。 弹簧（22,29,45）用于将装置的元件推向其静止位置。 体积固定的计量室由第二活塞和第二气缸形成，第二气缸和第二气缸能够在由位于气缸（16）的上端处的轴承限定的界限和由壁 的圆筒。

    METERING VALVE
    5.
    发明申请
    METERING VALVE 审中-公开
    计量阀

    公开(公告)号：WO2008090318A1

    公开(公告)日：2008-07-31

    申请号：PCT/GB2008/000197

    申请日：2008-01-21

    Applicant: CONSORT MEDICAL PLC ,  WARBY, Richard, John ,  ALLSOP, Paul ,  DICKENS, Colin ,  GLENTON, David, Jonathan ,  BAINTON, Michael, Cameron ,  DAY, Shane, Alistair ,  PERKINS, Robert ,  KELLY, Stuart, George, David

    Inventor： WARBY, Richard, John ,  ALLSOP, Paul ,  DICKENS, Colin ,  GLENTON, David, Jonathan ,  BAINTON, Michael, Cameron ,  DAY, Shane, Alistair ,  PERKINS, Robert ,  KELLY, Stuart, George, David

    IPC: F16K11/074

    CPC classification number: F16K11/074 ,  B05B3/025 ,  B05B3/026 ,  B05B12/06 ,  B65D83/262 ,  B65D83/54

    Abstract: A metering valve for a pressurised dispensing container comprising a metering chamber (5); an inlet (9) to the metering chamber; an outlet (10) to the metering chamber; one or more inlet sealing members (7) for sealing the inlet (9) to the metering chamber (5), and one or more outlet sealing members (8) for sealing the outlet (10) to themetering chamber (5). The metering chamber (5) is static and the one or more inlet sealing members (7) are rotatable between a first position, in which the inlet (9) to the metering chamber is open, and a second position, in which the inlet (9) to the metering chamber is closed, and the one or more outlet sealing members (8) are rotatable between a first position, in which the outlet (10) to the metering chamber is closed, and a second position, in which the outlet (10) to the metering chamber is open.

    Abstract translation: 一种用于加压分配容器的计量阀，包括计量腔（5）; 入口（9）到计量室; 出口（10）到计量室; 用于将入口（9）密封到计量室（5）的一个或多个入口密封构件（7）以及用于将出口（10）密封到定量室（5）的一个或多个出口密封构件（8）。 计量室（5）是静态的，并且一个或多个入口密封构件（7）可在第一位置（其中计量室的入口（9）打开）和第二位置之间旋转，在第二位置，入口 关闭计量室，并且一个或多个出口密封构件（8）可在其中关闭计量室的出口（10）的第一位置和第二位置之间旋转，在第二位置，出口 （10）到计量室是打开的。

    IMPROVEMENTS IN METERING VALVES FOR DISPENSERS
    6.
    发明申请
    IMPROVEMENTS IN METERING VALVES FOR DISPENSERS 审中-公开

    公开(公告)号：WO2006016151A3

    公开(公告)日：2006-02-16

    申请号：PCT/GB2005/003132

    申请日：2005-08-10

    Applicant: BESPAK PLC ,  WARBY, Richard, John

    Inventor： WARBY, Richard, John

    IPC: B65D83/14

    Abstract: A metering valve (1) is provided for a pressurised container (14) containing a pharmaceutical formulation. The valve has a stem (2) with a central flange (11) and a hollow open end (19) with a side port (20). The stem slides in a body (3) having larger and smaller diameter portions, and being closed off by a seal (4) against which the flange (11) rests in an inoperative position. A second seal is located around the-stem on the opposite side of the flange and trapped by a spring (6) which urges the stem into its inoperative position. When the stem is depressed, the inner seal (5) forms a sliding seal with the smaller diameter portion of the body to define a metering chamber (13) filled with the pharmaceutical. Continued depression opens the side hole (20) to allow the contents of the metering chamber to be dispensed, wherein at least one of the sealing gasket (8) or the inner seal (5) is formed as a co-moulding with at least a part of the valve body (3) or the valve stem, respectively.

    IMPROVEMENTS IN METERING VALVES FOR DISPENSERS
    8.
    发明申请
    IMPROVEMENTS IN METERING VALVES FOR DISPENSERS 审中-公开
    计量分配器阀门的改进

    公开(公告)号：WO2006016151A2

    公开(公告)日：2006-02-16

    申请号：PCT/GB2005003132

    申请日：2005-08-10

    Applicant: BESPAK PLC ,  WARBY RICHARD JOHN

    Inventor： WARBY RICHARD JOHN

    IPC: B65D83/14 ,  B67D7/84

    CPC classification number: B65D83/425 ,  B65D83/38 ,  B65D83/54

    Abstract: A metering valve (1) is provided for a pressurised container (14) containing a pharmaceutical formulation. The valve has a stem (2) with a central flange (11) and a hollow open end (19) with a side port (20). The stem slides in a body (3) having larger and smaller diameter portions, and being closed off by a seal (4) against which the flange (11) rests in an inoperative position. A second seal is located around the-stem on the opposite side of the flange and trapped by a spring (6) which urges the stem into its inoperative position. When the stem is depressed, the inner seal (5) forms a sliding seal with the smaller diameter portion of the body to define a metering chamber (13) filled with the pharmaceutical. Continued depression opens the side hole (20) to allow the contents of the metering chamber to be dispensed, wherein at least one of the sealing gasket (8) or the inner seal (5) is formed as a co-moulding with at least a part of the valve body (3) or the valve stem, respectively.

    Abstract translation: 为包含药物制剂的加压容器（14）提供计量阀（1）。 该阀具有带中心凸缘（11）的杆（2）和带有侧端口（20）的中空开口端（19）。 杆在具有较大直径部分和较小直径部分的主体（3）中滑动，并且通过密封件（4）封闭，法兰（11）搁置在密封件（4）处于非操作位置。 第二个密封件位于凸缘相对侧的杆周围，并被弹簧（6）捕获，弹簧（6）将杆推入其非工作位置。 当杆被压下时，内部密封件（5）与本体的较小直径部分形成滑动密封以限定填充有药物的计量室（13）。 继续按压打开侧孔（20）以允许配量室的内容物被分配，其中密封垫圈（8）或内密封件（5）中的至少一个形成为与至少一个 阀体（3）的一部分或阀杆。

    DISPENSING APPARATUS
    9.
    发明申请
    DISPENSING APPARATUS 审中-公开
    分配装置

    公开(公告)号：WO2005105187A1

    公开(公告)日：2005-11-10

    申请号：PCT/GB2005/001601

    申请日：2005-04-27

    Applicant: BESPAK PLC ,  WARBY, Richard, John

    Inventor： WARBY, Richard, John

    IPC: A61M15/00

    CPC classification number: A61M15/009 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0091 ,  A61M2205/0288 ,  A61M2205/3317 ,  A61M2205/8243 ,  A61M2206/14

    Abstract: A pressurised metered dose inhaler (1) comprising: a reservoir (2) for containing pressurised product, a valve (9) having an inlet (11) communicating with the reservoir and an outlet (14) through which product is dispensed in use, a piece of magnetisable material (5), an armature (8) extending into proximity with the valve, and an electromagnet (7) surrounding at least a portion of the armature. Wherein the armature is coupled to, or forms part of, the valve such that controlled energisation of the electromagnet causes the armature to be either attracted to or repelled from the piece of magnetisable material one or more times to operate the valve for a controlled time period to effect dispensation of a metered dose of pressurised product from the reservoir through the valve outlet.

    Abstract translation: 一种加压计量剂量吸入器（1），包括：用于容纳加压产品的储存器（2），具有与储存器连通的入口（11）的阀（9）和在使用中通过其分配产品的出口（14） 可磁化材料片（5），延伸到阀附近的电枢（8）以及围绕电枢的至少一部分的电磁体（7）。 其中电枢联接到阀门或形成阀的一部分，使得电磁体的受控通电使衔铁被吸引或者从可磁化材料排出一次或多次，以在可控制的时间段内操作阀门 以通过阀出口从储存器分配计量剂量的加压产品。

    DUAL COMPONENT DISPENSING APPARATUS
    10.
    发明申请
    DUAL COMPONENT DISPENSING APPARATUS 审中-公开
    双组分分配设备

    公开(公告)号：WO1996026126A1

    公开(公告)日：1996-08-29

    申请号：PCT/GB1996000376

    申请日：1996-02-20

    Applicant: BESPAK PLC ,  WARBY, Richard, John ,  CATER, Miro, Stan

    Inventor： BESPAK PLC

    IPC: B65D51/28

    CPC classification number: B65D51/2885 ,  Y10S215/08

    Abstract: This invention relates to apparatus for separately storing and subsequently mixing two components of a substance to be dispensed. The invention therefore comprises apparatus for separately storing and subsequently mixing first and second components of a substance to be dispensed, the apparatus comprising a container (2) defining a chamber (3) for receiving the first component (4), a closure member (6) connected to the container to close an outlet of the container, a vial (7) comprising a first portion (8) formed integrally with the closure member (6) and a second portion (9) releasably connected in sealing engagement with the first portion (8) to define therebetween a compartment (11) for receiving the second component (12), and vial opening means actuatable by movement of the closure member relative to the container to move the second portion out of sealing engagement with the first portion to thereby establish communication between the chamber and the compartment for mixing of the first and second components.

    Abstract translation: 本发明涉及用于分别储存和随后混合待分配物质的两种组分的装置。 因此，本发明包括用于分别存储和随后混合待分配物质的第一和第二组分的装置，该装置包括限定用于容纳第一组分（4）的室（3）的容器（2），封闭构件（6） ）连接到所述容器以关闭所述容器的出口;小瓶（7），包括与所述封闭构件（6）一体形成的第一部分（8）和与所述第一部分密封接合地可释放地连接的第二部分 （8），以在其间限定用于容纳第二部件（12）的隔间（11），以及通过封闭构件相对于容器的运动可启动的小瓶开启装置，以将第二部分移离与第一部分的密封接合 建立腔室和隔室之间的连通，以便混合第一和第二部件。

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