公开(公告)号：WO2008098206A1

公开(公告)日：2008-08-14

申请号：PCT/US2008/053482

申请日：2008-02-08

Applicant: ALTIVA CORPORATION ,  TRANSCENDENTAL SPINE, LLC ,  CASTELLVI, Antonio, E. ,  WEBB, Scott, A. ,  CORRANCE, Craig ,  KAPITAN, John ,  NIJENBANNING, Gert

Inventor： CASTELLVI, Antonio, E. ,  WEBB, Scott, A. ,  CORRANCE, Craig ,  KAPITAN, John ,  NIJENBANNING, Gert

IPC: A61B17/70

CPC classification number: A61B17/7023 ,  A61B17/7004 ,  A61B17/7025 ,  A61B17/7041

Abstract: A surgical implant device (100) for controlling the movement between a first bone or tissue portion and a second bone or tissue portion includes a first elongated member (102) connectable for movement with the first bone or tissue, portion and a second elongated member (108) connectable for movement with the first bone or tissue portion. The first elongated member and the second elongated member are connected by a flexible joint (210) configured to allow the first elongated member to pivot, move axially, and/or rotate relative to the second elongated member. At least one resilient member (240) is associated with the flexible joint to resist relative movement of the first elongated member relative to the second elongated member.

Abstract translation: 用于控制第一骨骼或组织部分与第二骨骼或组织部分之间运动的手术植入装置（100）包括可连接到第一骨骼或组织部分和第二细长部件 108）可连接以与第一骨骼或组织部分一起移动。 第一细长构件和第二细长构件通过柔性接头（210）连接，该柔性接头构造成允许第一细长构件相对于第二细长构件枢转，移动和/或旋转。 至少一个弹性构件（240）与柔性接头相关联，以抵抗第一细长构件相对于第二细长构件的相对运动。

公开(公告)号：WO2010047826A3

公开(公告)日：2011-06-09

申请号：PCT/US2009005781

申请日：2009-10-23

Applicant: TRIMERIS INC ,  BRAY BRIAN L ,  DI JIE ,  GREENBERG MICHAEL ,  HEILMAN DAVID ,  OHMSTEDE CAROL ,  SILINSKI PETER ,  WEBB SCOTT

Inventor： BRAY BRIAN L ,  DI JIE ,  GREENBERG MICHAEL ,  HEILMAN DAVID ,  OHMSTEDE CAROL ,  SILINSKI PETER ,  WEBB SCOTT

IPC: A61K9/00

CPC classification number: A61K38/162

Abstract: Provided herein are dosage formulations and dosing regimens of an antiviral peptide therapeutic, including methods of using the same.

Abstract translation: 本文提供了抗病毒肽治疗剂的剂型和给药方案，包括使用它们的方法。

公开(公告)号：WO2008098201A3

公开(公告)日：2008-10-30

申请号：PCT/US2008053475

申请日：2008-02-08

Applicant: ALTIVA CORP ,  TRANSCENDENTAL SPINE LLC ,  CASTELLVI ANTONIO E ,  WEBB SCOTT A ,  CORRANCE CRAIG ,  KAPITAN JOHN ,  NIJENBANNING GERT

Inventor： CASTELLVI ANTONIO E ,  WEBB SCOTT A ,  CORRANCE CRAIG ,  KAPITAN JOHN ,  NIJENBANNING GERT

IPC: A61B17/70 ,  A61B17/86

CPC classification number: A61B17/7035 ,  A61B17/7041

Abstract: A surgical implant device (310) that controls the relative movement between a first bone or tissue portion and a second bone or tissue portion. The device has a first connector member (340) connected for movement with the first bone or tissue portion and a second connector member (360) connected for movement with the second bone or tissue portion. A biasing member (388) pivotally connects the first connector member to the second connector member and resists the relative rotation between the first connector member and the second connector member.

Abstract translation: 一种手术植入装置（310），其控制第一骨骼或组织部分与第二骨骼或组织部分之间的相对运动。 该装置具有被连接以与第一骨骼或组织部分一起运动的第一连接器构件（340）和连接成与第二骨骼或组织部分一起移动的第二连接器构件（360）。 偏置构件（388）将第一连接器构件枢转地连接到第二连接器构件并抵抗第一连接器构件和第二连接器构件之间的相对旋转。

公开(公告)号：WO2008098201A2

公开(公告)日：2008-08-14

申请号：PCT/US2008/053475

申请日：2008-02-08

Applicant: ALTIVA CORPORATION ,  TRANSCENDENTAL SPINE, LLC ,  CASTELLVI, Antonio, E. ,  WEBB, Scott, A. ,  CORRANCE, Craig ,  KAPITAN, John ,  NIJENBANNING, Gert

Inventor： CASTELLVI, Antonio, E. ,  WEBB, Scott, A. ,  CORRANCE, Craig ,  KAPITAN, John ,  NIJENBANNING, Gert

IPC: A61B17/70 ,  A61B17/86

CPC classification number: A61B17/7035 ,  A61B17/7041

Abstract: A surgical implant device that controls the relative movement between a first bone or tissue portion and a second bone or tissue portion. The device has a first connector member connected for movement with the first bone or tissue portion and a second connector member connected for movement with the second bone or tissue portion. A biasing member pivotally connects the first connector member to the second connector member and resists the relative rotation between the first connector member and the second connector member.

Abstract translation: 一种手术植入装置，其控制第一骨骼或组织部分与第二骨骼或组织部分之间的相对运动。 该装置具有连接成与第一骨骼或组织部分一起移动的第一连接器构件和连接成与第二骨骼或组织部分一起移动的第二连接器构件。 偏置构件将第一连接器构件枢转地连接到第二连接器构件并抵抗第一连接器构件和第二连接器构件之间的相对旋转。

公开(公告)号：WO2005011539A2

公开(公告)日：2005-02-10

申请号：PCT/US2004023721

申请日：2004-07-22

Applicant: ABBOTT LAB ,  WEBB SCOTT A ,  MORENO ANTHONY P ,  MITCHELL MARGARET E ,  SMITH AARON C

Inventor： WEBB SCOTT A ,  MORENO ANTHONY P ,  MITCHELL MARGARET E ,  SMITH AARON C

IPC: A61B17/02 ,  A61B17/16 ,  A61B19/00 ,  A61F2/00 ,  A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61F2/44 ,  A61F2/46

CPC classification number: A61B17/1671 ,  A61B17/1659 ,  A61B2017/0256 ,  A61B2090/062 ,  A61F2/28 ,  A61F2/4465 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30059 ,  A61F2002/30062 ,  A61F2002/3008 ,  A61F2002/30133 ,  A61F2002/30308 ,  A61F2002/30324 ,  A61F2002/30326 ,  A61F2002/30538 ,  A61F2002/30604 ,  A61F2002/30616 ,  A61F2002/30677 ,  A61F2002/30787 ,  A61F2002/3082 ,  A61F2002/30894 ,  A61F2002/30904 ,  A61F2002/30924 ,  A61F2002/4475 ,  A61F2002/4623 ,  A61F2002/4624 ,  A61F2002/4627 ,  A61F2002/4635 ,  A61F2210/0004 ,  A61F2230/0015 ,  A61F2230/0063 ,  A61F2250/0006 ,  A61F2250/0036 ,  A61F2250/0037 ,  A61F2250/0098 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00179 ,  A61F2310/00359 ,  A61F2310/00407 ,  A61F2310/00796

Abstract: A spinal implant may be used to stabilize a portion of a spine. The implant may promote bone growth between adjacent vertebrae that fuses the vertebrae together. An implant may include an opening through a height of a body of the implant. The body of the implant may include curved sides. A top and/or a bottom of the implant may include protrusions that contact and/or engage vertebral surfaces to prevent backout of the implant from the disc space. A variety of instruments may be used to prepare a disc space and insert an implant. The instruments may include, but are not limited to, a distractor, a rasp, and one or more guides. The implant and instruments may be supplied in an instrument kit.

Abstract translation: 脊柱植入物可用于稳定脊柱的一部分。 植入物可以促进相邻椎骨之间的骨生长，所述骨骼将椎骨融合在一起。 植入物可以包括通过植入体的身体的高度的开口。 植入物的主体可以包括弯曲的侧面。 植入物的顶部和/或底部可以包括接触和/或接合脊椎表面的突起，以防止植入物从椎间盘空间中退出。 可以使用各种仪器来准备椎间盘空间并插入植入物。 仪器可以包括但不限于牵引器，锉刀和一个或多个引导件。 植入物和器械可以在仪器套件中提供。

公开(公告)号：WO2010047826A2

公开(公告)日：2010-04-29

申请号：PCT/US2009/005781

申请日：2009-10-23

Applicant: TRIMERIS, INC. ,  BRAY, Brian, L. ,  DI, Jie ,  GREENBERG, Michael ,  HEILMAN, David ,  OHMSTEDE, Carol ,  SILINSKI, Peter ,  WEBB, Scott

Inventor： BRAY, Brian, L. ,  DI, Jie ,  GREENBERG, Michael ,  HEILMAN, David ,  OHMSTEDE, Carol ,  SILINSKI, Peter ,  WEBB, Scott

IPC: A61K9/00

CPC classification number: A61K38/162

Abstract: Provided herein are dosage formulations and dosing regimens of an antiviral peptide therapeutic, including methods of using the same.

Abstract translation: 本文提供了抗病毒肽治疗剂的剂型和给药方案，包括使用它们的方法。

公开(公告)号：WO2008124013A1

公开(公告)日：2008-10-16

申请号：PCT/US2008/004307

申请日：2008-04-02

Applicant: TRIMERIS, INC. ,  BRAY, Brian, L. ,  DI, Jie ,  HEILMAN, David ,  SILINSKI, Peter ,  WEBB, Scott

Inventor： BRAY, Brian, L. ,  DI, Jie ,  HEILMAN, David ,  SILINSKI, Peter ,  WEBB, Scott

IPC: A61K47/48

CPC classification number: A61K38/162 ,  A61K9/0024 ,  A61K38/19 ,  A61K47/26 ,  A61K47/34 ,  A61K2300/00

Abstract: Provided herein are compositions and methods for their administration as therapeutic agents. In particular, provided herein are compositions and their use for the administration of antiviral peptide therapeutics.

Abstract translation: 本文提供了作为治疗剂施用的组合物和方法。 特别地，本文提供了组合物及其用于施用抗病毒肽治疗剂的用途。

公开(公告)号：WO2005011539A3

公开(公告)日：2005-02-10

申请号：PCT/US2004/023721

申请日：2004-07-22

Applicant: ABBOTT LABORATORIES ,  WEBB, Scott, A. ,  MORENO, Anthony, P. ,  MITCHELL, Margaret, E. ,  SMITH, Aaron, C.

Inventor： WEBB, Scott, A. ,  MORENO, Anthony, P. ,  MITCHELL, Margaret, E. ,  SMITH, Aaron, C.

IPC: A61F2/44

Abstract: A spinal implant (100) may be used to stabilize a portion of a spine. The implant may promote bone growth between adjacent vertebrae that fuses the vertebrae together. An implant may include an opening (112) through a height of a body of the implant. The body of the implant may include curved sides. A top and/or a bottom of the implant may include protrusions (130) that contact and/or engage vertebral surfaces to prevent backout of the implant from the disc space. A variety of instruments may be used to prepare a disc space and insert an implant. The instruments may include, but are not limited to, a distractor, a rasp, and one or more guides. The implant and instruments may be supplied in an instrument kit.