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    INSTANT READ-OUT BIOLOGICAL INDICATOR
    2.
    发明申请
    INSTANT READ-OUT BIOLOGICAL INDICATOR 审中-公开

    公开(公告)号：WO2020136608A1

    公开(公告)日：2020-07-02

    申请号：PCT/IB2019/061382

    申请日：2019-12-26

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： ERICKSON, Joshua D. ,  AHIMOU, Francois

    IPC: C12Q1/22

    Abstract: A self-contained sterilization process biological indicator is provided. The indicator includes a cuvette having at least one liquid-impermeable wall that forms an opening into a compartment, a predetermined number of sterilization process-resistant spores disposed in the compartment, a liquid medium disposed in the compartment, and a nucleic acid-interacting dye disposed in the compartment, with the proviso that the self-contained sterilization process biological indicator does not include an effective amount of germination medium and/or microbial growth medium. The opening is part of a pathway that permits passage of a sterilant gas into the compartment. The nucleic acid-interacting dye is fluorescent when bound to DNA or RNA. A method of using the self-contained sterilization process biological indicator to determine the effectiveness of a sterilization process is also provided.

    BIOLOGICAL INDICATOR FOR MONITORING A LOW-TEMPERATURE STERILIZATION PROCESS
    4.
    发明申请
    BIOLOGICAL INDICATOR FOR MONITORING A LOW-TEMPERATURE STERILIZATION PROCESS 审中-公开
    用于监测低温灭菌过程的生物指示剂

    公开(公告)号：WO2014133854A1

    公开(公告)日：2014-09-04

    申请号：PCT/US2014/017280

    申请日：2014-02-20

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： AHIMOU, Francois ,  BENNAARS-EIDEN, Assumpta ,  FOLTZ, William E. ,  SWAMINATHAN, Swarnalatha

    IPC: A61L2/28 ,  C12M1/34 ,  C12Q1/22

    CPC classification number: A61L2/28 ,  A61L2202/13 ,  C12M37/06 ,  C12Q1/22

    Abstract: An article and method are provided for assessing the efficacy of a sterilization process. The article comprises an outer container having an interior volume; a dry source of measurable biological activity disposed in the interior volume; and an effective amount of a dry agent for neutralizing a sterilant compound; wherein both the source of measurable biological activity and the agent are in vapor communication with an environment outside the outer container. The method comprises exposing the article to a first sterilant and, optionally, a second sterilant for a period of time and detecting the measurable biological activity.

    Abstract translation: 提供了一种用于评估灭菌过程的功效的制品和方法。 该制品包括具有内部容积的外部容器; 设置在内部容积中的可测量生物活性的干燥源; 和有效量的中和杀菌剂化合物的干燥剂; 其中可测量生物活性的来源和所述试剂与所述外部容器外部的环境蒸汽连通。 该方法包括将制品暴露于第一消毒剂和任选地第二消毒剂一段时间并检测可测量的生物活性。

    INSTANT READ-OUT BIOLOGICAL INDICATOR WITH GROWTH CONFIRMATION
    5.
    发明申请
    INSTANT READ-OUT BIOLOGICAL INDICATOR WITH GROWTH CONFIRMATION 审中-公开

    公开(公告)号：WO2020136613A1

    公开(公告)日：2020-07-02

    申请号：PCT/IB2019/061398

    申请日：2019-12-27

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： ERICKSON, Joshua D. ,  AHIMOU, Francois

    IPC: C12Q1/22

    Abstract: A self-contained sterilization process biological indicator is provided. The indicator includes a cuvette having at least one liquid-impermeable wall that forms an opening into a compartment, a nucleic acid-interacting dye disposed in the compartment, a predetermined number of sterilization process-resistant spores disposed in the compartment, a first liquid medium disposed in the compartment, and a nutrient composition that facilitates germination and/or outgrowth of a viable spore. The spores in the self-contained sterilization process biological indicator are contacting the dye. The nutrient composition is disposed in the compartment and isolated from the spores. The opening is part of a pathway that permits passage of a sterilant gas into the compartment. The nucleic acid-interacting dye is fluorescent when it interacts with DNA or RNA. A method of using the self-contained sterilization process biological indicator to determine the effectiveness of a sterilization process is also provided.

    BIOLOGICAL INDICATOR WITH ADJUSTED RESISTANCE CHARACTERISTICS
    8.
    发明申请
    BIOLOGICAL INDICATOR WITH ADJUSTED RESISTANCE CHARACTERISTICS 审中-公开

    公开(公告)号：WO2022263950A1

    公开(公告)日：2022-12-22

    申请号：PCT/IB2022/054856

    申请日：2022-05-24

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： AHIMOU, Francois ,  BOMMARITO, G. Marco ,  KOHMAN, Timothy A.

    IPC: A61L2/26 ,  A61L2/28 ,  C12M1/12 ,  C12Q1/00 ,  C12Q1/22 ,  G01N21/77

    Abstract: A biological sterilization indicator (BI) is provided. The BI can include a housing, and a container positioned in the housing. The BI can further include a first chamber, and a second chamber with a source of biological activity disposed therein. The BI can further include a substrate positioned in the housing between the first chamber and the second chamber. The substrate can be positioned in fluid communication with the first chamber and the second chamber, and the substrate can be further positioned such that the substrate is not in direct contact with the source of biological activity. The substrate can comprise a hydrophobic nonporous film having an aperture. The substrate and the aperture are dimensioned to control fluid flow between the first compartment and the second compartment. The substrate can extend around substantially the entire inner perimeter of the housing between the first compartment and the second compartment.

    CARRIER PIECE AND ENDOSCOPE CLEANING EFFICACY DETECTION DEVICE AND METHOD
    10.
    发明申请
    CARRIER PIECE AND ENDOSCOPE CLEANING EFFICACY DETECTION DEVICE AND METHOD 审中-公开
    载体片和内窥镜清洁效力检测装置和方法

    公开(公告)号：WO2018022497A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/043487

    申请日：2017-07-24

    Applicant: 3M INNOVATIVE PROPERTIES COMPANY

    Inventor： ZENG, Feng ,  LIU, Ting ,  AHIMOU, Francois ,  DUDA, RuthÃnn R. ,  LI, Kang ,  HU, Fangyuan

    IPC: A61B1/12 ,  B08B9/032

    CPC classification number: A61B1/125 ,  A61B1/00057 ,  A61B2090/701 ,  A61B2090/702

    Abstract: An embodiment of the present invention provides a carrier piece, and an endoscope cleaning efficacy detection device and method, belongs to the technical field of endoscope cleaning, and can solve the problems of inaccurate technical detection results, consuming much time, no real-time performance and troublesome operation of the existing endoscope cleaning efficacy detection. The carrier piece provided by an embodiment of the present invention is provided in an endoscope cleaning loop and has a support surface, the support surface having a simulation pollutant adhered thereon, and a structure of the carrier piece can at least enable a fluid flowing along the support surface to produce a turbulent flow. The endoscope cleaning efficacy detection device provided by an embodiment of the present invention comprises the carrier piece which is used in the endoscope cleaning efficacy detection method provided by the present disclosure.

    Abstract translation: 本发明实施例提供一种载体片和内窥镜清洗效能检测装置及方法，属于内窥镜清洗技术领域，可解决技术检测结果不准确，消耗 很多时间，现有内窥镜清洗效能检测没有实时性能和麻烦的操作。 本发明实施例提供的承载件设置在内窥镜清洗环中，并具有支撑面，支撑面上附着有模拟污染物，支撑件的结构至少能够使流体沿着 支撑表面产生湍流。 本发明实施例提供的内窥镜清洗效能检测装置，包括本发明提供的内窥镜清洗效能检测方法中使用的承载片。

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