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公开(公告)号:WO2020120714A1
公开(公告)日:2020-06-18
申请号:PCT/EP2019/084991
申请日:2019-12-12
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , ETTORRE, Anna , AHMED, Suaad , CRYAN, John , DINAN, Ted
IPC: A61K35/741 , A61K45/06 , A61P25/24
Abstract: The invention provides a composition comprising a bacterial strain of the genus Megasphaera, for use in the treatment or prevention of a disorder characterised by serotonin deficiency.
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公开(公告)号:WO2018229216A1
公开(公告)日:2018-12-20
申请号:PCT/EP2018/065858
申请日:2018-06-14
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , YUILLE, Samantha , ETTORE, Anna , AHMED, Suaad , FOTIADOU, Parthena , URCIA, Joseph Roby Iringan , SAVIGNAC, Helene
Abstract: The invention provides compositions comprising bacterial strains for treating and preventing neurodegenerative disorders.
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公开(公告)号:WO2017089794A1
公开(公告)日:2017-06-01
申请号:PCT/GB2016/053676
申请日:2016-11-23
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , HOLT, Amy Beth , MCCLUSKEY, Seanin Marie , LENNON, Grainne Clare , AHMED, Suaad
CPC classification number: A61K35/74 , A23C9/152 , A23L33/135 , A23V2002/00 , A61K9/19 , A61K31/00 , A61K39/08 , A61K39/39 , A61K2035/11 , A61K2039/542 , A61K2039/55594 , A61K2039/577 , A61K2039/58 , A61K2300/00
Abstract: The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
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公开(公告)号:WO2019215345A1
公开(公告)日:2019-11-14
申请号:PCT/EP2019/062236
申请日:2019-05-13
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , AHMED, Suaad , ETTORRE, Anna , REID, Sarah Anne , DINAN, Ted , CRYAN, John
IPC: A61K35/74 , A23L33/135 , A61P1/00 , A61P11/06 , A61P3/10 , A61P17/06 , A61P19/02 , A61P37/00 , A61P35/00 , A61P43/00
Abstract: The invention provides a composition comprising a bacterial strain of the genus Megasphaera , for use in the treatment or prevention of an autoimmune or inflammatory disorder or cancer
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公开(公告)号:WO2018229236A3
公开(公告)日:2018-12-20
申请号:PCT/EP2018/065903
申请日:2018-06-14
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , ETTORE, Anna , AHMED, Suaad , FOTIADOU, Parthena , YUILLE, Samantha , URCIA, Joseph Roby Iringan , SAVIGNAC, Helene
IPC: A61K35/74 , A61K35/745 , A61K35/747 , A61K31/19 , A61K31/192 , A61K31/194 , A61K31/203 , A61K9/19 , A61P25/00 , A61P25/28
Abstract: The invention provides compositions comprising commensal bacterial strains and organic acids and the uses thereof in the treatment of diseases.
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公开(公告)号:WO2022003057A1
公开(公告)日:2022-01-06
申请号:PCT/EP2021/068072
申请日:2021-06-30
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: DINAN, Ted , CRYAN, John , REID, Sarah , AHMED, Suaad , ETTORRE, Anna
Abstract: The invention provides compositions comprising one or more bacterial strains for treating or preventing a central nervous system disease or disorder.
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公开(公告)号:WO2020035623A1
公开(公告)日:2020-02-20
申请号:PCT/EP2019/072181
申请日:2019-08-19
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , ADRIANI, Marsilio , HOLT, Amy Beth , CHRISTOFI, Maria , COWIE, Philip , RAFTIS, Emma , LAUTE-CALY, Delphine Louise Claudette , HENNESSY, Emma Elizabeth Clare , AHMED, Suaad , ETTORRE, Anna
Abstract: The invention provides a composition comprising a bacterial strain for use in stimulating the immune system in a subject.
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公开(公告)号:WO2018229189A1
公开(公告)日:2018-12-20
申请号:PCT/EP2018/065809
申请日:2018-06-14
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , ETTORE, Anna , AHMED, Suaad , FOTIADOU, Parthena , URCIA, Joseph Roby Iringan , SAVIGNAC, Helene
IPC: A61K35/74 , A23L33/135 , A61P25/28
Abstract: The invention provides compositions comprising bacterial strains for treating and preventing a neurodegenerative disorder.
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公开(公告)号:WO2017085518A1
公开(公告)日:2017-05-26
申请号:PCT/GB2016/053620
申请日:2016-11-21
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: MULDER, Imke Elisabeth , HOLT, Amy Beth , MCCLUSKEY, Seanin Marie , LENNON, Grainne Clare , AHMED, Suaad
IPC: A61K35/744 , A61P35/00 , A61P29/00 , A61P37/00
CPC classification number: A61K35/74 , A23C9/1585 , A23L33/135 , A23V2002/00 , A61K9/0053 , A61K9/19 , A61K9/50 , A61K35/744 , A61K39/09 , A61K2035/11 , A61K2039/52 , A61K2039/585
Abstract: The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
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公开(公告)号:WO2020089488A1
公开(公告)日:2020-05-07
申请号:PCT/EP2019/080131
申请日:2019-11-04
Applicant: 4D PHARMA RESEARCH LIMITED
Inventor: HENNESSY, Emma Elizabeth Clare , AHMED, Suaad , HOLT, Amy Beth , COWIE, Philip , ETTORRE, Anna , YUILLE, Samantha , MULDER, Imke Elisabeth
Abstract: The invention provides compositions comprising bacterial strains for use as a vaccine adjuvant; for use in treating, preventing or delaying immunosenescence; or for use in enhancing a cell therapy, such as CAR-T. The invention also provides vaccine compositions comprising bacterial strains and one or more antigens.
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