专利检索 ap:("ALKERMES, INC.") AND inv:"MUGGE, Ingo, Andreas" 第 1 页

1.

发明申请
SUBSTITUTED CARBAMATE MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT 审中-公开

公开(公告)号：WO2022251304A8

公开(公告)日：2022-12-01

申请号：PCT/US2022/030841

申请日：2022-05-25

申请人： ALKERMES, INC.

发明人： PENNINGTON, Lewis, D. , CHOI, Younggi , HUYNH, Hoan , AQUILA, Brian, M. , MUGGE, Ingo, Andreas , HU, Yuan , WOODS, James, R. , RAYMER, Brian, Kenneth , BENTZIEN, Jörg, Martin , LEHMANN, Jonathan, Ward , HALE, Michael, R.

IPC分类号： C07D498/04 , A61K31/4353 , A61P21/00 , A61P43/00

摘要： The present invention provides compounds (I) useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

2.

发明申请
SUBSTITUTED FUSED BICYCLIC MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT 审中-公开

公开(公告)号：WO2022251302A1

公开(公告)日：2022-12-01

申请号：PCT/US2022/030839

申请日：2022-05-25

申请人： ALKERMES, INC.

发明人： HUYNH, Hoan , PENNINGTON, Lewis, D. , CHOI, Younggi , AQUILA, Brian, M. , MUGGE, Ingo, Andreas , HU, Yuan , WOODS, James, R. , RAYMER, Brian, Kenneth , BENTZIEN, Jörg Martin , LEHMANN, Jonathan Ward , HALE, Michael, R.

IPC分类号： A61P43/00 , C07D498/08 , C07D498/18 , A61K31/4353 , A61K31/4162 , A61K31/519

摘要： The present invention provides compounds useful as orexin-2 receptor agonists for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

3.

发明申请
SUBSTITUTED AMIDE MACROCYCLIC COMPOUNDS WITH OREXIN-2 RECEPTOR AGONIST ACTIVITY 审中-公开

公开(公告)号：WO2022232025A1

公开(公告)日：2022-11-03

申请号：PCT/US2022/026144

申请日：2022-04-25

申请人： ALKERMES, INC.

发明人： CHOI, Younggi , HU, Yuan , HUYNH, Hoan , AQUILA, Brian, M. , RAYMER, Brian, Kenneth , MUGGE, Ingo, Andreas , WOODS, James, R. , PENNINGTON, Lewis, D. , BENTZIEN, Jörg, Martin , LEHMANN, Jonathan, Ward , HALE, Michael, R. , VALIULIN, Roman, A.

IPC分类号： A61P25/00 , C07D498/04 , C07D498/14 , A61K31/4353

摘要： The present invention provides compounds of formula (I) useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

4.

发明申请
SUBSTITUTED PIPERIDINO COMPOUNDS AND RELATED METHODS OF TREATMENT 审中-公开

公开(公告)号：WO2022140317A1

公开(公告)日：2022-06-30

申请号：PCT/US2021/064484

申请日：2021-12-21

申请人： ALKERMES, INC.

发明人： PENNINGTON, Lewis, D. , CHOI, Younggi , HUYNH, Hoan , AQUILA, Brian, M. , MUGGE, Ingo, Andreas , HU, Yuan , WOODS, James, R. , RAYMER, Brian, Kenneth , BENTZIEN, Jörg, Martin , LEHMANN, Jonathan, Ward , KARRA, Srinivasa , VALIULIN, Roman A. , MATHARU, Daljit

IPC分类号： C07D211/58 , C07D401/04 , C07D401/06 , C07D401/14 , C07D471/04 , C07D487/04 , C07D498/04 , A61K31/4545 , A61P25/26

摘要： The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

5.

发明申请
SUBSTITUTED MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT 审中-公开

公开(公告)号：WO2022140316A1

公开(公告)日：2022-06-30

申请号：PCT/US2021/064483

申请日：2021-12-21

申请人： ALKERMES, INC.

发明人： PENNINGTON, Lewis, D. , CHOI, Younggi , HUYNH, Hoan , AQUILA, Brian, M. , MUGGE, Ingo, Andreas , HU, Yuan , WOODS, James, R. , RAYMER, Brian, Kenneth , BENTZIEN, Jörg, Martin , LEHMANN, Jonathan, Ward , HALE, Michael, R. , KARRA, Srinivasa , VALIULIN, Roman, A. , MATHARU, Daljit

IPC分类号： C07D498/04 , C07D498/14 , A61P41/00 , A61K31/4353

摘要： The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.