BLOCKING THE EFFECT OF TERATOGENS ON A FETUS
    2.
    发明申请
    BLOCKING THE EFFECT OF TERATOGENS ON A FETUS 审中-公开
    阻断TERATOGENS对一个FET的影响

    公开(公告)号:WO1991016905A1

    公开(公告)日:1991-11-14

    申请号:PCT/US1991003137

    申请日:1991-05-07

    CPC classification number: A61K31/70 A61K31/715

    Abstract: By administration of sulfated cyclodextrin on a pregnant mother, the effect of a teratogen on a developing fetus is blocked. Blocking the effect of the teratogen reduces congenital defects in a developing fetus. The sulfated cyclodextrin has also been found to reduce the effect of the teratogen on a host. The sulfated cyclodextrin is administered either before or after onset of organogenesis and either before or after exposure to the teratogen. Teratogens include radiation, temperature extremes, chemicals, drugs, bacteria, viruses, hormones, stress, injury, pregnancy and fatigue.

    CYCLODEXTRIN REFINING PROCESS
    4.
    发明申请
    CYCLODEXTRIN REFINING PROCESS 审中-公开
    环糊精精制方法

    公开(公告)号:WO1995000556A1

    公开(公告)日:1995-01-05

    申请号:PCT/US1994006393

    申请日:1994-06-07

    CPC classification number: C08B37/0012

    Abstract: Cyclodextrins are refined by performing a crystallization step in the presence of a hydrogen bond inhibitor. The hydrogen bond inhibitor includes a base in a amount to adjust the pH of the solution to 8 and above or a non-base such as urea, guanidium hydrochloride and sodium lauryl sulfate in an amount of 0.1 % to 2 %.

    Abstract translation: 通过在氢键抑制剂的存在下进行结晶步骤来精制环糊精。 氢键抑制剂包括以0.1〜2%的量将溶液的pH调节至8以上的碱或碱,例如脲,盐酸胍和月桂基硫酸钠的碱。

    PROCESS FOR SEPARATING CYCLODEXTRIN FROM A COMPLEX
    8.
    发明申请
    PROCESS FOR SEPARATING CYCLODEXTRIN FROM A COMPLEX 审中-公开
    从复合物中分离环糊精的方法

    公开(公告)号:WO1994020542A1

    公开(公告)日:1994-09-15

    申请号:PCT/US1994002211

    申请日:1994-03-01

    CPC classification number: C08B37/0012 A23L5/273

    Abstract: The process entails adding salt in an amount of 1 % to 5 % by weight slurry to an aqueous slurry of cyclodextrin-guest complex at a temperature of 100 DEG C to 150 DEG C for a period of 5 minutes to 2 hours and a pressure of 15 psia to 70 psia to prevent the slurry from boiling and to cause the complex to break apart. The individual cyclodextrin and guest are then recovered.

    Abstract translation: 该方法需要在100℃至150℃的温度下,将1至5重量%的浆料加入到环糊精 - 客体络合物的水性浆料中5分钟至2小时的压力 15 psia至70 psia,以防止浆料沸腾并导致复合物分解。 然后回收各个环糊精和客体。

    HAZE-FREE CYCLODEXTRINS
    10.
    发明申请
    HAZE-FREE CYCLODEXTRINS 审中-公开
    无水循环

    公开(公告)号:WO1993010255A1

    公开(公告)日:1993-05-27

    申请号:PCT/US1992009531

    申请日:1992-11-06

    CPC classification number: C12P19/14 C12P19/18

    Abstract: A cyclodextrin which when added to water produces a haze-free solution is made by the use of starch which contains at least about 90 % amylopectin in a two-stage process wherein first a starch hydrolysate is formed by means of an alpha-amylase or an acid and a second subsequent step wherein the cyclodextrin is formed by means of a cyclodextrin-glycosyl-transferase.

    Abstract translation: 当加入到水中时产生无霾溶液的环糊精通过使用在两阶段方法中含有至少约90%支链淀粉的淀粉来制备,其中首先通过α-淀粉酶形成淀粉水解产物或 酸和第二后续步骤,其中环糊精通过环糊精 - 糖基转移酶形成。

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