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1.发明申请METHODS FOR IMPROVING MILK PRODUCTION BY ADMINISTRATION OF MICROBIAL CONSORTIA 审中-公开通过微生物联合管理提高奶产量的方法
公开(公告)号：WO2017120495A1
公开(公告)日：2017-07-13
申请号：PCT/US2017/012573
申请日：2017-01-06
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： EMBREE, Mallory , PICKING, Luke , GOGUL, Grant , TARASOVA, Janna
CPC classification number: A61K36/064 , A23K10/18 , A23K40/35 , A23K50/10 , A61K9/0019 , A61K9/0053 , A61K35/74 , A61K35/742 , A61K36/06
Abstract: The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.
Abstract translation: 本公开涉及分离的微生物 - 包括微生物 - 微生物聚生体的新菌株，以及包含其的组合物。 此外，本公开教导了在调节反刍动物中乳和乳组分的产量和产量的方法中使用所述微生物，微生物聚生体和包含其的组合物的方法。 在具体的方面，本公开内容提供了增加反刍动物中乳的期望组分的方法。 此外，本公开提供了调节瘤胃微生物组的方法。
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2.发明申请
公开(公告)号：WO2019079629A9
公开(公告)日：2019-04-25
申请号：PCT/US2018/056563
申请日：2018-10-18
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： EMBREE, Mallory , GOGUL, Grant , MARTINO, Cameron , PITT, Norm
Abstract: The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.
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公开(公告)号：WO2018126026A1
公开(公告)日：2018-07-05
申请号：PCT/US2017/068740
申请日：2017-12-28
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： EMBREE, Mallory , GAFFNEY, James Russell , MARTINO, Cameron Joseph
Abstract: Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and synthesizing bioreactive modificators based thereon are disclosed. Methods for identifying and utilizing pathways and functionalities of interest based thereon are also disclosed.
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Patent Agency Ranking4.发明申请
公开(公告)号：WO2018201049A1
公开(公告)日：2018-11-01
申请号：PCT/US2018/029953
申请日：2018-04-27
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： EMBREE, Mallory , MARTINO, Cameron , PITT, Norman , EMBREE, Jordan , DODGE, Corey
Abstract: The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.
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5.发明申请METHODS FOR IMPROVING AGRICULTURAL PRODUCTION OF FOWL BY ADMINISTRATION OF MICROBIAL CONSORTIA OR PURIFIED STRAINS THEREOF 审中-公开通过施用微生物联合或其纯化菌株来改进农业生产福利的方法
公开(公告)号：WO2017181203A1
公开(公告)日：2017-10-19
申请号：PCT/US2017/028015
申请日：2017-04-17
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： EMBREE, Mallory , TARASOVA, Janna , PICKING, Luke , GOGUL, Grant , VANDERLINDEN, Kayla
IPC: A61K35/74 , A61K35/747 , C12N1/20 , C12R1/225
Abstract: The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.
Abstract translation: 本公开涉及分离的微生物 - 包括微生物 - 微生物聚生体的新菌株，以及包含其的组合物。 此外，本公开教导了在调节家禽产量，抗病性和产蛋量的方法中使用所述微生物，微生物聚生体和包含其的组合物的方法。 在具体的方面，本公开提供了增加饲料效率的方法，以及防止致病微生物定居的方法。
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公开(公告)号：WO2018126036A1
公开(公告)日：2018-07-05
申请号：PCT/US2017/068758
申请日：2017-12-28
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： EMBREE, Mallory
Abstract: Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.
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公开(公告)号：WO2018126033A1
公开(公告)日：2018-07-05
申请号：PCT/US2017/068753
申请日：2017-12-28
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： EMBREE, Mallory , MARTINO, Cameron Joseph
Abstract: Methods, apparatuses, and systems for analyzing microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and diagnostics and biostate management based thereon are disclosed. Methods for diagnostics, analytics, and treatments of states and state aberrations/deviations, including treatments, such as bioreactive modificators, such as bioreactive modificators comprising synthetic microbial ensembles, are also disclosed.
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8.发明申请METHODS, APPARATUSES, AND SYSTEMS FOR ANALYZING MICROORGANISM STRAINS FROM COMPLEX HETEROGENEOUS COMMUNITIES, PREDICTING AND IDENTIFYING FUNCTIONAL RELATIONSHIPS AND INTERACTIONS THEREOF, AND SELECTING AND SYNTHESIZING MICROBIAL ENSEMBLES BASED THEREON 审中-公开用于分析复杂异构群落微生物菌株的方法，装置和系统，预测和识别功能关系及其相互作用，并选择和合成基于其的微生物基因
公开(公告)号：WO2016210251A1
公开(公告)日：2016-12-29
申请号：PCT/US2016/039221
申请日：2016-06-24
Applicant: ASCUS BIOSCIENCES, INC.
Inventor： ZENGLER, Karsten , EMBREE, Mallory
CPC classification number: C12Q1/06 , A23K10/16 , A23K10/18 , A23K50/10 , A23K50/30 , A23K50/75 , A61K35/74 , C12Q1/6874 , C12Q1/689 , C12Q2600/158 , C12Q2600/178
Abstract: Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and synthesizing microbial ensembles based thereon are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.
Abstract translation: 公开了用于从复杂异质社区筛选，分析和选择微生物的方法，装置和系统，预测和鉴定其功能关系及其相互作用，并基于此合成微生物集合体。 还公开了确定和确定微生物类型和菌株的绝对细胞计数的方法，以及确定活性微生物与环境参数之间的网络关系。
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