公开(公告)号：WO2018169683A1

公开(公告)日：2018-09-20

申请号：PCT/US2018/020202

申请日：2018-02-28

Applicant: BOSTON SCIENTIFIC SCIMED, INC. ,  BOSTON SCIENTIFIC LIMITED

Inventor： AGRAWAL, Sumit ,  BHATNAGAR, Mayank ,  TOMAR, Peeyush ,  NAYAK, Poornachandra ,  CHABRA, Anshul

IPC: A61M39/06

CPC classification number: A61M39/0613 ,  A61M39/06 ,  A61M39/0693 ,  A61M2039/0633 ,  A61M2039/064 ,  A61M2039/0686 ,  A61M2207/00

Abstract: Hemostasis valves and methods for making and using hemostasis valves are disclosed. An example hemostasis valve may include a main body having a distal end region and a proximal end region. A first seal member may be disposed within the proximal end region of the main body. A cartridge may be at least partially disposed within the proximal end region of the main body. The cartridge may include a second seal member. A plunger may be coupled to the proximal end region of the main body. A rotation limiting member may be positioned adjacent to the proximal end region of the main body. A tab member may be positioned adjacent to the proximal end region of the main body. The tab member may be designed to rotate relative to the proximal end region of the main body until the tab member engages the rotation limiting member.

公开(公告)号：WO2018169685A1

公开(公告)日：2018-09-20

申请号：PCT/US2018/020214

申请日：2018-02-28

Applicant: BOSTON SCIENTIFIC SCIMED, INC. ,  BOSTON SCIENTIFIC LIMITED

Inventor： AGRAWAL, Sumit ,  TOMAR, Peeyush

IPC: A61M39/06

CPC classification number: A61M39/0613 ,  A61M39/06 ,  A61M39/0693 ,  A61M2039/062 ,  A61M2039/0633 ,  A61M2039/064 ,  A61M2039/0686 ,  A61M2207/00

Abstract: Hemostasis valves and methods for making and using hemostasis valves are disclosed. An example hemostasis valve may include a main body having a distal end region and a proximal end region. A first seal member may be disposed within the proximal end region of the main body. A cartridge may be at least partially disposed within the proximal end region of the main body. The cartridge may include a second seal member. The cartridge may have one or more projections formed thereon. The proximal end region of the main body may have one or more recesses formed therein. The one or more recesses may be designed to engage the one or more projections. A plunger may be coupled to the proximal end region of the main body.

公开(公告)号：WO2018089390A1

公开(公告)日：2018-05-17

申请号：PCT/US2017/060479

申请日：2017-11-07

Applicant: BOSTON SCIENTIFIC SCIMED, INC ,  BOSTON SCIENTIFIC LIMITED

Inventor： AGRAWAL, Sumit ,  PEPIN, Henry J. ,  REDDY, Somashekar

IPC: A61M25/00 ,  A61M29/00 ,  A61M39/06

Abstract: A hemostasis valve for use in a medical device. The hemostasis valve may include a generally cylindrical body having a proximal side, a distal side, and a thickness extending therebetween. The proximal side may include a tapered central region having a surface sloped towards a center of the body and the distal side may include a distally extending curved central region.

Abstract translation:

一种用于医疗器械的止血阀。 止血阀可以包括具有近侧，远侧和在其间延伸的厚度的大致圆柱形主体。 近侧可以包括具有朝向身体中心倾斜的表面的锥形中心区域，并且远侧可以包括向远侧延伸的弯曲中心区域。

公开(公告)号：WO2018089388A1

公开(公告)日：2018-05-17

申请号：PCT/US2017/060475

申请日：2017-11-07

Applicant: BOSTON SCIENTIFIC SCIMED, INC ,  BOSTON SCIENTIFIC LIMITED

Inventor： AGRAWAL, Sumit ,  KATHRANI, Biten

IPC: A61M39/06

Abstract: A hemostasis valve assembly for use in a medical device. The hemostasis valve assembly may include a main body portion defining an internal cavity, a seal cartridge disposed within the internal cavity, and a low pressure valve assembly positioned within the internal cavity adjacent to the seal cartridge. The low pressure valve assembly may include a first valve member having a first valve body and a second valve member having second valve body. A portion of a distal side of the first valve member may abut at least a portion of a proximal side of the second valve member.

Abstract translation: 用于医疗装置的止血阀组件。 止血阀组件可以包括限定内部空腔的主体部分，设置在内部空腔内的密封盒以及定位在邻近密封盒的内腔内的低压阀组件。 低压阀组件可以包括具有第一阀体的第一阀构件和具有第二阀体的第二阀构件。 第一阀构件的远侧的一部分可以邻接第二阀构件的近侧的至少一部分。

公开(公告)号：WO2012118526A1

公开(公告)日：2012-09-07

申请号：PCT/US2011/052804

申请日：2011-09-22

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： BOISMIER, Dennis, A. ,  AGRAWAL, Sumit ,  MEYER, Michael, P. ,  RADHAKRISHNAN, Rajesh

IPC: A61F2/90

CPC classification number: A61F2/915 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91541 ,  A61F2002/91575 ,  A61F2250/0036

Abstract: In at least one embodiment, a stent comprises an expandable framework comprising a plurality of serpentine bands and a plurality of connector struts. Each serpentine band comprises a plurality of alternating struts and turns. A plurality of the serpentine bands each have their proximal turns aligned on a common stent circumference and comprise first distal turns and second distal turns. The first distal turns are aligned with one another on a common stent circumference. The second distal turns aligned with one another on another common stent circumference. Each band in the plurality comprises first struts and second struts. Each first strut is attached between a proximal turn and a first distal turn, and each second strut is attached between a proximal turn and a second distal turn. The second struts are wider than said first struts.

Abstract translation: 在至少一个实施例中，支架包括包括多个蛇形带和多个连接器支柱的可扩展框架。 每个蛇形带包括多个交替的支柱和匝。 多个蛇形带各自具有在共同的支架圆周上对齐的近端匝，并且包括第一远端匝和第二远端匝。 第一远端匝在共同的支架圆周上彼此对准。 第二个远端匝在另一个共同的支架圆周上彼此对准。 多个中的每个带包括第一支柱和第二支柱。 每个第一支柱连接在近端匝和第一远端匝之间，并且每个第二支柱附接在近匝和第二远端匝之间。 第二支柱比所述第一支柱宽。

公开(公告)号：WO2016040382A1

公开(公告)日：2016-03-17

申请号：PCT/US2015/049029

申请日：2015-09-08

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： AGRAWAL, Sumit ,  MADITHETI, Nawaz ,  PETERSEN, Eric M. ,  OOMMEN, Stephen J. ,  SCHMIDT, James A.

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2002/9534 ,  A61F2220/0008

Abstract: A medical device (10) may include an elongate delivery sheath (12) and a valve replacement implant (16) disposed within a lumen of the delivery sheath, the implant including an anchor member (70) reversibly actuatable between a delivery configuration and a deployed configuration. The implant may include at least one locking element (58) configured to lock the anchor member in the deployed configuration, and at least one actuator element (84) configured to engage the at least one locking element and actuate the anchor member between the delivery configuration and the deployed configuration. The at least one actuator element may include an unlocking member (50) configured to compress a first locking portion of the at least one locking element to unlock the anchor member from the deployed configuration.

Abstract translation: 医疗装置（10）可以包括细长输送护套（12）和设置在输送护套的内腔内的瓣膜置换植入物（16），所述植入物包括锚定构件（70），可在输送构型和部署 组态。 所述植入物可以包括构造成将锚定构件锁定在展开构型中的至少一个锁定元件（58），以及至少一个构造成与所述至少一个锁定元件接合并致动所述锚固构件的致动元件（84） 和部署的配置。 所述至少一个致动器元件可以包括解锁构件（50），所述解锁构件被构造成压缩所述至少一个锁定元件的第一锁定部分，以将所述锚固构件从展开构型解锁。

公开(公告)号：WO2016115375A1

公开(公告)日：2016-07-21

申请号：PCT/US2016/013449

申请日：2016-01-14

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： O'CONNOR, Tim ,  O'SULLIVAN, Richard ,  FLANNERY, Art ,  INO, Takashi H. ,  FOSTER, Daniel J. ,  ROHL, James P. ,  MCAFEE, Patricia ,  FEELEY, Marc ,  AGRAWAL, Sumit ,  DARST, John ,  BOYHAN, Noel

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0008 ,  A61F2220/0033

Abstract: A medical device system (10) may include a valve replacement implant including an anchor member (70) reversibly actuatable between a delivery configuration and a deployed configuration, wherein the implant includes at least one locking element (58) configured to lock the anchor member in the deployed configuration, and at least one actuator element (84) configured to engage the at least one locking element and actuate the anchor member between the delivery configuration and the deployed configuration. The at least one actuator element may include a self-biased cam mechanism (86) configured to extend into and engage a first locking portion of the at least one locking element.

Abstract translation: 医疗设备系统（10）可以包括阀替换植入物，其包括可在输送构型和展开构型之间可逆地致动的锚定构件（70），其中植入物包括构造成将锚定构件锁定在至少一个中的至少一个锁定元件 所述部署结构以及至少一个致动器元件（84）被配置为接合所述至少一个锁定元件并且在所述输送配置和所述展开配置之间致动所述锚固构件。 所述至少一个致动器元件可以包括被配置为延伸到所述至少一个锁定元件的第一锁定部分并且接合所述至少一个锁定元件的第一锁定部分的自偏置凸轮机构（86）。

公开(公告)号：WO2016028588A1

公开(公告)日：2016-02-25

申请号：PCT/US2015/044991

申请日：2015-08-13

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： AGRAWAL, Sumit ,  GULER, Ismail ,  FLYNN, David M. ,  CHOUINARD, Paul F. ,  MERDAN, Kenneth M.

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/243 ,  A61F2210/0014 ,  A61F2210/0057 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0041 ,  A61F2230/0004 ,  A61F2230/0017 ,  A61F2230/0021 ,  A61F2230/005 ,  A61F2230/0056 ,  A61F2230/0058 ,  A61F2230/0069 ,  A61F2240/001

Abstract: A transcatheter valve frame (10) comprising a valve frame comprising an elongate tubular member having a longitudinal axis and a circumference, the elongate tubular member comprising a plurality of struts (16) interconnected by peaks (18a) and valleys (18b) that define a closed cell construction comprising a plurality of interconnected cells (14), the valve frame is formed from a single piece of material comprising a metal or metal alloy, the valve frame having a diameter that increases upon axial compression and the valve frame comprising a locking mechanism integral with the valve frame configured to fix the diameter of the valve frame.

Abstract translation: 经导管阀框架（10）包括阀框架，所述阀架包括具有纵向轴线和圆周的细长管状构件，所述细长管状构件包括多个通过峰（18a）和谷（18b）互连的支柱（16），所述多个支柱 闭孔结构包括多个互连的电池（14），所述阀架由包括金属或金属合金的单块材料形成，所述阀架具有在轴向压缩时增加的直径，并且所述阀框架包括锁定机构 与构造成固定阀框直径的阀框一体。

公开(公告)号：WO2014182946A2

公开(公告)日：2014-11-13

申请号：PCT/US2014/037364

申请日：2014-05-08

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： AGRAWAL, Sumit ,  THAKUR, Pramodsingh Hirasingh ,  RAAB, David ,  ZHANG, Steve Hongxi ,  SCHAUER, Travis J.

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B5/01 ,  A61B5/02158 ,  A61B5/4836 ,  A61B5/6847 ,  A61B2018/0022 ,  A61B2018/00375 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00714 ,  A61B2018/00779 ,  A61B2018/00797 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/00892 ,  A61B2018/1472 ,  A61B2018/1497 ,  A61B2090/065 ,  A61B2562/0271 ,  A61B2562/043 ,  G01K11/3206 ,  G01K13/002 ,  G02B6/02204

Abstract: A medical system configured for nerve modulation can include an elongate shaft, having a distal end region and a proximal end region is disclosed. Adjacent the distal end region an ablation electrode can be disposed. The system can further include a first optical fiber, having a proximal end and a distal end, extending along an outer surface of the elongate shaft, and in turn a number of (fiber Bragg Grating) FBG sensors therein. The FBG sensors can be positioned adjacent to the ablation electrode. An optical read out mechanism can be optically coupled to the optical fiber to transmit light into the optical fiber and detect light reflected from the FBG sensor. Here, the detected light, reflected from FBG temperature sensors, encodes local temperatures at each of the FBG temperature sensors.

Abstract translation: 配置用于神经调节的医疗系统可以包括具有远端区域和近端区域的细长轴。 邻近远端区域可以设置消融电极。 该系统还可以包括具有近端和远端的第一光纤，其沿着细长轴的外表面延伸，并且还具有多个（光纤布拉格光栅）FBG传感器。 FBG传感器可以位于消融电极附近。 光学读出机构可以光耦合到光纤以将光传输到光纤中并检测从FBG传感器反射的光。 在这里，从FBG温度传感器反射的检测光编码每个FBG温度传感器的局部温度。

公开(公告)号：WO2018169670A1

公开(公告)日：2018-09-20

申请号：PCT/US2018/019712

申请日：2018-02-26

Applicant: BOSTON SCIENTIFIC LIMITED ,  PEPIN, Henry J.

Inventor： PEPIN, Henry J. ,  AGRAWAL, Sumit

IPC: A61M39/06

CPC classification number: A61M39/0613 ,  A61M5/007 ,  A61M39/06 ,  A61M39/0606 ,  A61M2039/064 ,  A61M2039/0673

Abstract: Hemostasis valves and methods for making and using hemostasis valves are disclosed. An example hemostasis valve may include a main body having a proximal end region. A cartridge may be at least partially disposed within the proximal end region. The cartridge including a seal member. The cartridge may have a proximal member, a distal member, and may define a seal holding region. The seal member may have an axial thickness of about 0.04 to about 0.2 inches. The seal member may be secured within the seal holding region by a mechanical bond.