公开(公告)号：WO2017035215A3

公开(公告)日：2017-04-20

申请号：PCT/US2016048360

申请日：2016-08-24

Applicant: CARDIAC PACEMAKERS INC

Inventor： KANE MICHAEL J ,  LINDER WILLIAM J ,  BALCZEWSKI RON A ,  MI BIN ,  HATLESTAD JOHN D ,  HUELSKAMP PAUL ,  MAILE KEITH R

IPC: A61N1/375 ,  A61B5/00 ,  A61N1/365 ,  A61N1/372

CPC classification number: A61N1/36542 ,  A61B5/02028 ,  A61B5/0402 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/6869 ,  A61N1/36514 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3702 ,  A61N1/37205 ,  A61N1/37235 ,  A61N1/3756

Abstract: Implantable devices having motion sensors. In some examples the a configuration is generated for the implantable device to use the motion sensor in an energy preserving mode in which one or more axis of detection of the motion sensor is disabled or ignored. In some examples the motion sensor outputs along multiple axes are analyzed to determine which axes best correspond to certain patient parameters including patient motion/activity and/or cardiac contractility. In other examples the output of the motion sensor is observed across patient movements or postures to develop conversion parameters to determine a patient standard frame of reference relative to outputs of the motion sensor of an implanted device.

Abstract translation: 具有运动传感器的可植入设备。 在一些示例中，为可植入设备生成配置，以在能量保持模式下使用运动传感器，其中运动传感器的一个或多个检测轴被禁用或忽略。 在一些示例中，分析沿着多个轴的运动传感器输出以确定哪些轴最佳地对应于某些患者参数，包括患者运动/活动和/或心脏收缩性。 在其他示例中，在患者移动或姿势上观察运动传感器的输出，以产生转换参数以相对于植入设备的运动传感器的输出确定患者标准参照系。

公开(公告)号：WO2015191893A3

公开(公告)日：2016-04-14

申请号：PCT/US2015035389

申请日：2015-06-11

Applicant: CARDIAC PACEMAKERS INC

Inventor： KANE MICHAEL J ,  STAHMANN JEFFREY E ,  MAILE KEITH R

IPC: A61N1/365 ,  A61N1/05 ,  A61N1/368 ,  A61N1/372 ,  G06F17/30

CPC classification number: A61N1/36585 ,  A61N1/0563 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/3684 ,  A61N1/37288 ,  A61N1/3756

Abstract: Systems and methods for providing rate responsive pacing therapy to a heart of a patient. One example method for providing rate responsive pacing therapy includes sensing cardiac electrical data with a leadless cardiac pacemaker (LCP) that is implanted within or proximate the heart. From this location, the LCP may provide pacing therapy to the heart based at least in part on the sensed cardiac electrical data. An implantable medical device located remotely from the heart may sense patient activity, and may wirelessly communicate patient activity data from the implantable medical device to the LCP, sometimes using conducted communication. The LCP may be then determine an adjustment to the provided pacing therapy (e.g. adjust the pacing rate) based at least in part on the received patient activity data signal.

Abstract translation: 用于向患者的心脏提供速率响应起搏治疗的系统和方法。 用于提供速率响应起搏治疗的一个示例性方法包括用植入心脏内或心脏附近的无引线心脏起搏器（LCP）来感测心脏电数据。 从该位置，LCP可以至少部分地基于所感测的心脏电数据来向心脏提供起搏治疗。 位于远离心脏的可植入医疗装置可以感测患者活动，并且可以有时使用进行的通信将患者活动数据从可植入医疗装置无线地传送到LCP。 然后，LCP可以至少部分地基于所接收的患者活动数据信号来确定对所提供的起搏治疗的调整（例如调整起搏速率）。

公开(公告)号：WO2015191886A3

公开(公告)日：2016-04-07

申请号：PCT/US2015035378

申请日：2015-06-11

Applicant: CARDIAC PACEMAKERS INC

Inventor： STAHMANN JEFFREY E ,  MAILE KEITH R ,  KANE MICHAEL J ,  LINDER WILLIAM J ,  SIMMS HOWARD D

IPC: A61N1/372 ,  A61B5/00 ,  A61B5/0464 ,  A61N1/375 ,  A61N1/39

CPC classification number: A61N1/3962 ,  A61B5/0464 ,  A61B5/4836 ,  A61N1/3621 ,  A61N1/37205 ,  A61N1/37288 ,  A61N1/3756 ,  A61N1/3987

Abstract: Systems and methods for coordinating treatment of abnormal heart activity using multiple implanted devices within a patient. In one example, a leadless cardiac pacemaker (LCP) may receive signals related to one or more physiological conditions of a patient, wherein the LCP may be configured to deliver ATP therapy to a heart. The LCP may also be configured, based at least in part on the received signals, to detect an arrhythmia. In response to detecting an arrhythmia, the LCP may determine whether to deliver ATP therapy to the heart. If the LCP determines to deliver ATP therapy, the LCP may deliver ATP therapy to the heart.

Abstract translation: 使用患者内的多个植入装置协调异常心脏活动治疗的系统和方法。 在一个示例中，无引线心脏起搏器（LCP）可以接收与患者的一个或多个生理状况相关的信号，其中所述LCP可被配置为向心脏递送ATP治疗。 至少部分地基于所接收的信号也可以配置LCP以检测心律失常。 响应于检测心律失常，LCP可以确定是否向心脏递送ATP治疗。 如果LCP决定提供ATP治疗，LCP可以向心脏递送ATP治疗。

公开(公告)号：WO2014137684A3

公开(公告)日：2014-10-30

申请号：PCT/US2014018542

申请日：2014-02-26

Applicant: CARDIAC PACEMAKERS INC

Inventor： SWEENEY MOIRA B ,  KANE MICHAEL J ,  FOUHY JAMES

IPC: A61N1/375

CPC classification number: A61N1/3752 ,  A61N1/375 ,  H01R13/33 ,  H01R43/20 ,  H01R2101/00 ,  Y10T29/49826

Abstract: An apparatus includes an implantable housing, a header mounted to the implantable housing and including a connector block cavity, and a connector block located within the connector block cavity, the connector block including a plastic housing portion, a coil spring, and a metallic termination member connected to the coil spring and exposed outside the plastic housing portion.

Abstract translation: 一种装置包括可植入壳体，安装到可植入壳体并包括连接器块空腔的插头和位于连接器块腔内的连接器块，连接器块包括塑料壳体部分，螺旋弹簧和金属端接构件 连接到螺旋弹簧并暴露在塑料壳体部分的外部。

公开(公告)号：WO2016033197A2

公开(公告)日：2016-03-03

申请号：PCT/US2015046971

申请日：2015-08-26

Applicant: CARDIAC PACEMAKERS INC

Inventor： STAHMANN JEFFREY E ,  KANE MICHAEL J ,  HUELSKAMP PAUL ,  MAILE KEITH R

IPC: A61N1/37 ,  A61N1/372 ,  A61N1/375 ,  A61N1/39

CPC classification number: A61N1/3962 ,  A61N1/3702 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/3756 ,  A61N1/3925 ,  A61N1/3956

Abstract: An implantable cardiac rhythm system includes a first implantable medical device configured to detect a first heartbeat from a first location, and a second implantable medical device configured to detect the first heart beat of the patient from a second location. The second implantable medical device, upon detecting the first heart beat, may communicate an indication of the detected first heart beat to the first implantable medical device, and in response, the first implantable medical device may institute a blanking period having a blanking period duration such that a T-wave of the detected first heart beat is blanked out by the first implantable medical device so as to not be interpreted as a subsequent second heart beat. In some instances, the first implantable medical device is an SICD and the second implantable medical device is a LCP.

Abstract translation: 可植入心脏节律系统包括被配置为检测来自第一位置的第一心跳的第一可植入医疗设备以及被配置为从第二位置检测患者的第一心跳的第二可植入医疗设备。 第二植入式医疗设备在检测到第一心脏跳动时可以将检测到的第一心跳的指示传达给第一植入式医疗设备，并且作为响应，第一植入式医疗设备可以设置具有消隐周期持续时间的消隐时段 所检测到的第一心跳的T波被第一可植入医疗装置消隐以便不被解释为随后的第二心跳。 在一些情况下，第一可植入医疗装置是SICD并且第二可植入医疗装置是LCP。

公开(公告)号：WO2013090301A3

公开(公告)日：2013-08-29

申请号：PCT/US2012069039

申请日：2012-12-12

Applicant: CARDIAC PACEMAKERS INC

Inventor： KANE MICHAEL J ,  O'ROURKE JOHN ,  ENRIGHT EION ,  SWEENEY MOIRA B ,  NOLAN DARAGH ,  ENGLISH JAMES MICHAEL

IPC: A61N1/375 ,  H01R3/00

CPC classification number: A61N1/05 ,  A61N1/3752 ,  H01R13/405 ,  H01R13/5224 ,  H01R24/76 ,  H01R43/00 ,  Y10T29/49004

Abstract: Systems and methods for implantable medical devices and headers are described. In an example, an implantable medical device includes a device container including an electronic module within the device container. A header core includes a bore hole portion and at least two electronic connection features disposed within the bore hole portion. The bore hole portion includes at least one cavity configured to allow placement of at least one of the electronic connection features within the bore hole portion. The at least two electronic connection features are electrically coupled to the electronic module within the device container. The header core is configured to allow location of the at least two electronic connection features in a selected configuration within the bore hole portion. A header shell is disposed around the header core and attached to the device container.

Abstract translation: 描述了可植入医疗装置和集管的系统和方法。 在一个示例中，可植入医疗装置包括在装置容器内包括电子模块的装置容器。 集管芯包括钻孔部分和设置在钻孔部分内的至少两个电连接特征。 所述钻孔部分包括至少一个空腔，其被配置为允许将所述电子连接部件中的至少一个放置在所述钻孔部分内。 该至少两个电子连接特征电耦合到设备容器内的电子模块。 集管芯被配置为允许在钻孔部分内以选定的构造定位至少两个电子连接特征。 集管壳体围绕集管芯设置并附接到设备容器。

公开(公告)号：WO2013090300A3

公开(公告)日：2013-08-29

申请号：PCT/US2012069038

申请日：2012-12-12

Applicant: CARDIAC PACEMAKERS INC

Inventor： KANE MICHAEL J ,  O'ROURKE JOHN ,  ENGLISH JAMES MICHAEL

IPC: A61N1/375

CPC classification number: A61N1/375 ,  A61N1/37229 ,  A61N1/3752

Abstract: Systems and methods for implantable medical devices and headers are described. In an example, an implantable medical device includes a device container including an electronic module within the device container. A header core includes an electronic connection feature electrically coupled to the electronic module within the device container, the electronic connection feature configured to engage with a lead. In some examples, the header core includes a tag holder configured to locate an identification tag in a selected position with respect to the header core. In some examples, the header core includes an antenna attachment feature configured to locate an antenna in a selected position with respect to the header core. A header shell is disposed around the header core and attached to the device container.

Abstract translation: 描述了可植入医疗装置和集管的系统和方法。 在一个示例中，可植入医疗装置包括在装置容器内包括电子模块的装置容器。 标头芯包括电耦合到设备容器内的电子模块的电子连接特征，电子连接特征被配置为与引线接合。 在一些示例中，标题核心包括标签保持器，其被配置为将识别标签相对于标题核心定位在选定位置。 在一些示例中，标题核心包括被配置为将天线定位在相对于标题核心的选定位置的天线附件特征。 集管壳体围绕集管芯设置并附接到设备容器。

公开(公告)号：WO2007146489A3

公开(公告)日：2008-02-14

申请号：PCT/US2007066916

申请日：2007-04-19

Applicant: CARDIAC PACEMAKERS INC ,  SHUROS ALLAN C ,  KANE MICHAEL J

Inventor： SHUROS ALLAN C ,  KANE MICHAEL J

IPC: A61B5/03 ,  A61B5/00 ,  A61B5/07 ,  A61N1/365

CPC classification number: A61B5/03 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14546 ,  A61B5/415 ,  A61B5/418 ,  A61B5/4839 ,  A61N1/3627 ,  A61N1/36514

Abstract: A device and method are disclosed for physiological monitoring of the lymphatic system. An implantable device is configured with a lymphatic sensor disposed in a lymphatic vessel for sensing pressure, flow, and/or the concentration of particular markers within the vessel. The device may be further configured to deliver appropriate therapy in accordance with the lymphatic monitoring.

Abstract translation: 公开了用于淋巴系统的生理监测的装置和方法。 可植入装置配置有设置在淋巴管中的淋巴传感器，用于感测容器内的特定标记物的压力，流量和/或浓度。 该装置还可以被配置成根据淋巴监测进行适当的治疗。