公开(公告)号：WO2015017255A1

公开(公告)日：2015-02-05

申请号：PCT/US2014/048075

申请日：2014-07-24

Applicant: DANISCO US INC.

Inventor： FOUKARAKI, Maria ,  HOMMES, Ronaldus Wilhelmus ,  KAPER, Thijs ,  KELEMEN, Bradley R. ,  KRALJ, Slavko ,  LANTZ, Suzanne E. ,  NIKOLAEV, Igor ,  VAN DER KLEY, Wilhelmus ,  VAN LIESHOUT, Johannes Franciscus Thomas ,  VAN STIGT THANS, Sander

IPC: C12N9/02 ,  C12N9/42

CPC classification number: C12N9/2437 ,  C12N9/2434 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004

Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.

Abstract translation: 公开了糖基水解酶变体，特别是糖基水解酶家族61的某些氧化还原酶的变体。编码糖基水解酶变体的核酸，包括糖基水解酶变体的组合物，产生变体的方法以及 也描述了使用变体。

公开(公告)号：WO2015017256A1

公开(公告)日：2015-02-05

申请号：PCT/US2014/048077

申请日：2014-07-24

Applicant: DANISCO US INC.

Inventor： FOUKARAKI, Maria ,  HOMMES, Ronaldus Wilhelmus ,  KAPER, Thijs ,  KELEMEN, Bradley R. ,  KRALJ, Slavko ,  LANTZ, Suzanne E. ,  NIKOLAEV, Igor ,  VAN DER KLEY, Wilhelmus ,  VAN LIESHOUT, Johannes Franciscus Thomas ,  VAN STIGT THANS, Sander

IPC: C12N9/02 ,  C12N9/42

CPC classification number: C12N9/2437 ,  C12N9/2434 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004

Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.

公开(公告)号：WO2015017254A1

公开(公告)日：2015-02-05

申请号：PCT/US2014/048067

申请日：2014-07-24

Applicant: DANISCO US INC.

Inventor： DOUGLAS, Nicholai ,  FOUKARAKI, Maria ,  HOMMES, Ronaldus Wilhelmus ,  KAPER, Thijs ,  KELEMEN, Bradley R. ,  KRALJ, Slavko ,  LANTZ, Suzanne E. ,  LASSILA, Jonathan K. ,  NIKOLAEV, Igor ,  TORRES-PAZMINO, Daniel Esteban ,  VAN DER KLEY, Wilhelmus ,  VAN LIESHOUT, Johannes Franciscus Thomas ,  VAN STIGT THANS, Sander

IPC: C12N9/02 ,  C12N9/42

CPC classification number: C12N9/2437 ,  C12N9/2434 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004

Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.

Abstract translation: 公开了糖基水解酶酶变体，特别是糖基水解酶家族的某些氧化还原酶的变体。61.还描述了编码糖基水解酶变体的核酸，包括糖基水解酶变体的组合物，产生变体的方法和使用变体的方法。

公开(公告)号：WO2014093294A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/074030

申请日：2013-12-10

Applicant: DANISCO US INC.

Inventor： BOTT, Richard R. ,  FOUKARAKI, Maria ,  HOMMES, Ronaldus ,  KAPER, Thijs ,  KELEMEN, Bradley R. ,  KRALJ, Slavko ,  NIKOLAEV, Igor ,  SANDGREN, Mats ,  VAN LIESHOUT, Johannes ,  VAN STIGT THANS, Sander

IPC: C12N9/42 ,  C12P19/14 ,  C11D3/386 ,  C12N15/80

CPC classification number: C12N9/2437 ,  A23K20/189 ,  C11D3/38645 ,  C12N9/2434 ,  C12P19/02 ,  C12P19/14 ,  C12P2203/00 ,  C12Y302/01004 ,  C12Y302/01091

Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1 ), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

Abstract translation: 公开了Hypocrea jecorina Cel7A（以前的里氏木霉纤维二糖水解酶I或CBH1）的许多同源物和变体，编码它们的核酸及其制备方法。 同系物和变体纤维素酶具有7A族糖基水解酶的氨基酸序列，其中一个或多个氨基酸残基被取代和/或缺失。

公开(公告)号：WO2014093275A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/074005

申请日：2013-12-10

Applicant: DANISCO US INC.

Inventor： BOTT, Richard R. ,  FOUKARAKI, Maria ,  HOMMES, Ronaldus ,  KAPER, Thijs ,  KELEMEN, Bradley R. ,  KRALJ, Slavko ,  NIKOLAEV, Igor ,  SANDGREN, Mats ,  VAN LIESHOUT, Johannes ,  VAN STIGT THANS, Sander

IPC: C12N9/42

CPC classification number: C12P19/14 ,  C12N9/2434 ,  C12N9/2437 ,  C12P19/02 ,  C12Y302/01091

Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

Abstract translation: 公开了红褐肉座菌Cel7A（以前称为里氏木霉纤维二糖水解酶I或CBH1）的许多同系物和变体，编码它们的核酸及其制备方法。 同系物和变体纤维素酶具有家族7A的糖基水解酶的氨基酸序列，其中一个或多个氨基酸残基被取代和/或缺失。

公开(公告)号：WO2014093287A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/074020

申请日：2013-12-10

Applicant: DANISCO US INC.

Inventor： BOTT, Richard R. ,  FOUKARAKI, Maria ,  HOMMES, Ronaldus ,  KAPER, Thijs ,  KELEMEN, Bradley R. ,  KRALJ, Slavko ,  NIKOLAEV, Igor ,  SANDGREN, Mats ,  VAN LIESHOUT, Johannes ,  VAN STIGT THANS, Sander

IPC: C12N9/42 ,  C12P19/14 ,  C11D3/386 ,  C12N15/80

CPC classification number: C12N9/2437 ,  C11D3/38645 ,  C11D3/38681 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01091 ,  C12Y302/01099

Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

公开(公告)号：WO2014093282A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/074014

申请日：2013-12-10

Applicant: DANISCO US INC.

Inventor： BOTT, Richard, R. ,  FOUKARAKI, Maria ,  HOMMES, Ronaldus ,  KAPER, Thijs ,  KELEMEN, Bradley, R. ,  KRALJ, Slavko ,  NIKOLAEV, Igor ,  SANDGREN, Mats ,  VAN LIESHOUT, Johannes ,  VAN STIGT THANS, Sander

IPC: C12N9/42

CPC classification number: C12N9/2437 ,  C12N9/2402 ,  C12N9/2434 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004

Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1 ), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

Abstract translation: 公开了Hypocrea jecorina Cel7A（以前称为里氏木霉纤维二糖水解酶I或CBH1）的许多同系物和变体，编码它们的核酸和 生产方法。 同系物和变体纤维素酶具有家族7A的糖基水解酶的氨基酸序列，其中一个或多个氨基酸残基被取代和/或缺失。

公开(公告)号：WO2014093281A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/074011

申请日：2013-12-10

Applicant: DANISCO US INC.

Inventor： BOTT, Richard R. ,  FOUKARAKI, Maria ,  HOMMES, Ronaldus ,  KAPER, Thijs ,  KELEMEN, Bradley R. ,  KRALJ, Slavko ,  NIKOLAEV, Igor ,  SANDGREN, Mats ,  VAN LIESHOUT, Johannes ,  VAN STIGT THANS, Sander

IPC: C12N9/24 ,  C12N9/42

CPC classification number: C12N9/2437 ,  C12N9/2434 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004

Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

Abstract translation: 公开了许多Hypocrea jecorina Cel7A（以前的里氏木霉纤维二糖水解酶I或CBH1）的同源物和变体，编码它们的核酸及其制备方法。 同系物和变体纤维素酶具有7A族糖基水解酶的氨基酸序列，其中一个或多个氨基酸残基被取代和/或缺失。