Abstract:
A system and method to generate ultrashort high beam quality pulses from spatio- temporally mode-locked multimode fiber laser are described. The invention relies on engineering the intra-cavity pulse propagation in a multimode laser cavity to shape the spatial and temporal properties of the output pulses. The invention allows the generation of Kerr-induced self-beam cleaning when mode-locking is obtained. Using this invention, high power ultrashort pulses can be achieved with a Gaussian mode profile by using commercially available multimode fibers.
Abstract:
A system for capturing solar light of the sun, whereby the solar light comprises a short wavelength light component and a long wavelength light component. The system comprises at least a lens (101), a light- guide (102), and a self-adaptive coupling feature (103). The at least one lens is arranged adjacent to the light-guide in order to focus the long wavelength component onto the self-adaptive coupling feature, and the self-adaptive coupling feature is configured to couple the short wavelength light component into the light-guide.
Abstract:
A multimode waveguide illuminator and imager relies on a wave front shaping system that acts to compensate for modal scrambling and light dispersion by the multimode waveguide. A first step consists of calibrating the multimode wave¬ guide and a second step consists in projecting a specific pattern on the wave¬ guide proximal end in order to produce the desire light pattern at its distal end. The illumination pattern can be scanned or changed dynamically only by chang¬ ing the phase pattern projected at the proximal end of the waveguide. The third and last step consists in collecting the optical information, generated by the sample, through the same waveguide in order to form an image. Known free space microscopy technique can be adapted to endoscopy with multimode waveguide, such as, but not limited to, fluorescence imaging or Raman spectros¬ copy or imaging, 3D linear scattering imaging or two-photon imaging. Super- resolution, i.e., resolution below the diffraction limit, is achieved for example but not limited to, using the STimulated Emission Depletion microscopy (STED) technique or the Structured Illumination Microscopy (SIM) technique or a stochastic illumination based method (PALM, STORM) in combination with the multimode waveguide imaging method.
Abstract:
The invention relates to oblique transscleral illumination of an eye fundus with at least one physical point light source around the eye allowing for dark field imaging combined with optical coherence tomography imaging.
Abstract:
The invention discloses systems and methods for generation of microfluidic jets providing a tool for very precise and localized delivery of e.g., medicaments. The proposed solution overcomes shortcomings related to miniaturization of a jet injection technology by implementing laser energy as a driving mechanism and optical fibers for its delivery. Solving the step of miniaturization can allow building new tools compatible with minimally invasive surgical techniques, high parallelization of jet injection units or design of new ergonomic injection devices.
Abstract:
The present invention is related to a method and apparatus for the volumetric fabrication of three-dimensional objects or articles from photoresponsive materials loaded with scattering particles, by adjusting the refractive index of said photoresponsive material (12) so as to match the refractive index of said scattering particles (30), and/or using a light source emitting light of a wavelength longer than 630 nm, preferably in a range from 630 nm to 1050 nm, more preferably in a range from 650 nm to 900 nm.
Abstract:
A method for producing a three-dimensional object comprising computing a sequence of back-projections describing the three-dimensional object to be formed from different orientation angles of said object, defining a sequence of patterns of light using said back-projections, and irradiating with each of said patterns of light at the respective corresponding orientation angle and according to the defined sequence a photoresponsive material that is capable of alteration of its material phase upon irradiation by light, thereby creating a three-dimensional distribution of alterations within the photoresponsive medium which physically reproduces said three- dimensional object, thereby creating the three-dimensional object.
Abstract:
A method for monitoring the generation of a three-dimensional object (5) being formed in a tomographic additive manufacturing system from simulated tomographic two-dimensional back-projections (9) of a desired 3D article comprises the steps of: - illuminating a container (3) comprising a photoresponsive material (103) with a light beam (2a) of two-dimensional light patterns generated from said two-dimensional back-projections (9) at multiple angles, preferably by rotation of the container (3), so as to form the object (5) in the container (3); - capturing images of said object (5) being formed by volumetric printing with an imaging system (6, 7, 8) disposed around the container (3) in which the object (5) is being formed; - determining from said images the shape or extent to which the object has been formed.
Abstract:
A method for imaging a tissue of an eye, the method including the steps of providing oblique illumination to the eye by a plurality of light emitting areas of a light delivery device, the plurality of light emitting areas being independently controllable and arranged to direct light towards at least one of a retina and an iris of the eye, causing an output beam from light backscattered from the at least one of the retina and the iris by the oblique illumination, capturing the output beam with an imaging system to provide a sequence of images of a fundus of the eye, and retrieving a phase and absorption contrast image from the sequence of images of the fundus, wherein the sequence of images of the fundus of the step of capturing is obtained by sequentially turning on one or more of the plurality of light emitting areas at a time in the step of providing the oblique illumination.
Abstract:
The design of a proximity sensor to be integrated into cochlea implants is described. The sensor allows the anticipation of contact between the cochlear implant and intracochlear structures, including the cochlear canal wall and basilar membrane, providing a feedback or an alarm to the surgeon performing the implant insertion such that trauma to the cochlea is avoided. This helps to preserve any residual hearing ability in patients who receive the surgical implant.