DETECTION DEVICE, METHOD, KIT, APPARATUS AND SYSTEM FOR DETECTING PRESENCE OF PATHOGENIC MICROORGANISMS AND CORRESPONDING ANTIBODIES IN A BIOLOGICAL SAMPLE

    公开(公告)号:WO2022029682A1

    公开(公告)日:2022-02-10

    申请号:PCT/IB2021/057209

    申请日:2021-08-05

    Applicant: ELTEK S.P.A.

    Abstract: A device (1) for detecting presence of at least one pathogenic microorganism and/or at least one corresponding antibody in a biological sample comprises: - a body (2), - at least one first detection member (5A) and one second detection member (5B) on said body (2) and designed to bind said at least one pathogenic microorganism and/or said at least one corresponding antibody, - at least one fluidic circuit (6) in said body (2), comprising at least one introduction portion (3B, 4B, 7) for introducing said biological sample, wherein at least one first circuit branch (6') and one second circuit branch (6") extend from the at least one introduction portion (3B, 4B, 7) to receive at least one first fraction and one second fraction of the biological sample, respectively. The first and second circuit branches (6', 6") and the first and second detection members (5A, 5B) are configured in a manner such that the first fraction is susceptible to reach the first detection member (5 A) and the second fraction is susceptible to reach the second detection member (5B). One of the first circuit branch (6') and the second circuit branch (6") comprises a dissociation chamber (6B) for performing a dissociation of complexes from among said at least one pathogenic microorganism and said at least one corresponding antibody possibly present in the biological sample.

    MEDICAL DEVICE, IN PARTICULAR FOR THE SEPARATION OF A FLUID
    2.
    发明申请
    MEDICAL DEVICE, IN PARTICULAR FOR THE SEPARATION OF A FLUID 审中-公开
    医疗设备,特别是用于分离流体

    公开(公告)号:WO2015071852A2

    公开(公告)日:2015-05-21

    申请号:PCT/IB2014/066015

    申请日:2014-11-13

    Applicant: ELTEK S.P.A.

    Abstract: A medical device for separating a fluid, in particular for separating platelet-rich plasma from whole blood, comprises three containers (10, 20, 30) and at least one corresponding connection line (40) having an intermediate bifurcation (41). Provided on the connection line (40) are valve means (42, 45, 47a, 48a-48b) for enabling or preventing a flow of fluid. At least one container (10) comprises a hollow container body (11) and a plunger (12) associated in a movable way to the container body (11). The device (1) has a modular structure comprising a plurality of modules (A, B, C), which are connected together in a separable way, for enabling separation thereof according to the step of use of the device (1), and include at least one first module (A), which comprises at least the first container (10) and a corresponding portion (40a) of the first connection line (40), and a second module (B), which comprises at least one between the second and third containers (30, 20) with a corresponding portion (40b, 40c) of the first connection line (40). Provided at least at the interface between two modules (A, B, C) of the modular structure are releasable connectors (43, 44), in particular hydraulic connectors comprising at least two parts that can be coupled together, each of which belongs to a corresponding module (A, B, C).

    Abstract translation: 用于分离流体的医疗装置,特别是用于从全血中分离富含血小板的血浆的医疗装置包括三个容器(10,20,30)和至少一个具有中间分叉(41)的对应连接管线(40)。 在连接线(40)上设有用于使流体流动的阀装置(42,45,47a,48a-48b)。 至少一个容器(10)包括中空容器主体(11)和以可移动的方式与容器主体(11)相关联的柱塞(12)。 装置(1)具有包括多个模块(A,B,C)的模块化结构,它们以可分离的方式连接在一起,以便根据装置(1)的使用步骤使其分离,并且包括 至少一个第一模块(A),其至少包括第一容器(10)和第一连接线(40)的对应部分(40a),以及第二模块(B),其包括: 第二和第三容器(30,20),其具有第一连接线(40)的对应部分(40b,40c)。 提供至少在模块化结构的两个模块(A,B,C)之间的界面处是可释放的连接器(43,44),特别是包括至少两个可以耦合在一起的部件的液压连接器,每个部件属于 相应的模块(A,B,C)。

    WASHING AGENT DISPENSER FOR DISHWASHING MACHINES

    公开(公告)号:WO2021245618A1

    公开(公告)日:2021-12-09

    申请号:PCT/IB2021/054918

    申请日:2021-06-04

    Applicant: ELTEK S.P.A.

    Abstract: A washing agent dispenser for washing machines has a dispenser body (100, 200) designed for mounting in a washing machine wash-chamber (3), in the dispenser body (100, 200) being defined at least a containment volume capable of containing a washing agent. The dispenser also comprises: - a dispensing arrangement configured to dispense one or more dosed amounts of the washing agent, - a circuit arrangement configured for connection to a control system of a washing machine on which the dispenser itself can be installed, - an operable part ( 1041, 1042; 100), configured to be moved manually by a user at least from a first position to a second position, - a locking/unlocking arrangement, which includes a locking mechanism (2061, 2Ο62, 451, 4531, 4532, 454) drivable by a corresponding electric actuator (450), to assume at least one operative condition and at least one inoperative condition, in which the locking mechanism prevents or enables, respectively, a displacement of the operable part (1041, 1042; 100) from the first position to the second position. The circuit arrangement is configured for enabling control of the electric actuator (450), for causing the locking mechanism to pass (2061, 2Ο62, 451, 4531, 4532, 454) from the at least one operative condition to the at least one inoperative condition, depending on an electrical signal provided by at least one of a sensor device belonging to the circuit arrangement and the control system of the washing machine (1).

    WASHING AGENT DISPENSER FOR DISHWASHING MACHINES

    公开(公告)号:WO2021245617A1

    公开(公告)日:2021-12-09

    申请号:PCT/IB2021/054915

    申请日:2021-06-04

    Applicant: ELTEK S.P.A.

    Abstract: A washing agent dispenser for washing machines comprises a fixed dispenser part (200), designed for mounting on a wall delimiting a washing machine wash- chamber, and a removable dispenser part (100), couplable in a removable way to the fixed dispenser part (200). The removable dispenser part (100) comprises a hollow body (101) defining at least one containment volume for a washing agent (WD, WA). The dispenser (10) also comprises at least one signalling arrangement (207, 260, 261), which includes at least one emitting device (207, 260) on the fixed dispenser part (200), which is capable of emitting a visible radiation, the emitting device (207, 260) including a light source (260). The at least one signalling arrangement (207, 260, 261) further comprises at least one light-guide element (261) configured to transfer the visible radiation emitted by the emitting device (207, 260) towards an area of the dispenser (10) designed to face inside the washing machine wash-chamber (3), the at least one light-guide element (261) being on the removable dispenser part (100) and being optically coupled in a separable way to the emitting device (207, 260).

    SENSORIZED SUPPORTING DEVICE FOR BEARINGS
    5.
    发明申请

    公开(公告)号:WO2020105010A1

    公开(公告)日:2020-05-28

    申请号:PCT/IB2019/060075

    申请日:2019-11-22

    Applicant: ELTEK S.P.A.

    Abstract: A sensorized supporting device for bearings (1) comprises: • a bearing housing (2), configured for being secured to a mounting structure and defining at least one seat (2c) for a bearing (3); and • a sensorized supporting base (4), having a supporting body (4') prearranged for being at least partially positioned between the mounting structure (S) and the bearing housing (2). The supporting body (4') has a detection surface (4c) which extends in a longitudinal direction (L) and a transverse direction (W) and is configured for resting, directly or via interposition of at least one further element, on a corresponding surface of one of the bearing housing (2) and the mounting structure, the supporting base (4) being provided with a mechanical-stress sensor. The mechanical-stress sensor comprises at least one piezoelectric transducer (10 1 , 10 2 , 20) defining at least part of the detection surface (4c), the at least one piezoelectric transducer (10; 20;10 1 , 10 2 ) being configured for generating an electrical potential difference that is substantially proportional to the magnitude of a mechanical stress (SS) applied to the bearing housing (2).

    A LEVEL SENSOR FOR DETECTING THE LEVEL OF A MEDIUM

    公开(公告)号:WO2020070690A1

    公开(公告)日:2020-04-09

    申请号:PCT/IB2019/058432

    申请日:2019-10-03

    Applicant: ELTEK S.P.A.

    Abstract: A sensor for detecting the level of a generic medium comprises an electrical-connection structure and at least one level-detection structure. The level-detection structure comprises a plurality of elongated electrodes (3 1 -3 4 ), which include at least three measuring electrodes (3 1 -3 4 ). The elongated electrodes (3 1 -3 4 ) extend at least partially in positions where they are generally set alongside one another in a length direction of the level-detection structure and each have a proximal end and a distal end relative to the electrical-connection structure. The level-detection structure is divided, in the length direction, into a succession of detection sections (S1-S3), each of which includes two effective portions (EP 1 -EP 2; EP 1 -EP 3; EP 2 -EP 4 ) of two respective such measuring electrodes (3I-34), the two effective portions (EP 1 -EP 2 ; EP 1 -EP 3 ; EP 2 -EP 4 ) extending to a prevalent extent substantially parallel to one another at a first predetermined distance (d1). In one or more first detection sections (S2-S3) there also extends a non- effective portion (NEP 1 , NEP 2 , NEP 3 ) of at least one further elongated electrode other than the two measuring electrodes that define the two effective portions (EP 1 -EP 2 ; EP 1 -EP 3 ; EP 2 -EP 4 ) of the corresponding first detection section (S2-S3). The elongated electrodes (3 1 -3 4 ) are shaped in such a way that, at one or more of said first detection sections (S2-S3), the non-effective portion (NEP 1 , NEP 2 , NEP 3 ) of the at least one further elongated electrode extends to a prevalent extent at respective second predetermined distances (d2) from the corresponding said two effective portions (EP 1 -EP 2 ; EP 1 -EP 3 ; EP 2 -EP 4 ), the second predetermined distances (d2) being greater than the first predetermined distance (d1).

    A MICRO-FLUIDIC DEVICE FOR CONCENTRATION OF PARTICLES

    公开(公告)号:WO2019234657A1

    公开(公告)日:2019-12-12

    申请号:PCT/IB2019/054683

    申请日:2019-06-05

    Applicant: ELTEK S.P.A.

    Abstract: A microfluidic device for concentrating particles contained in a fluid sample comprises a substrate (11) having a surface where at least one microfluidic arrangement (M) is defined, which comprises: - a loading chamber (14), for loading the fluid sample into the at least one microfluidic arrangement (M); - a plurality of microchannels (13), which have respective inlet ends connected to the loading chamber (14); and - a covering element (12), which is substantially impermeable to the fluid sample and extends at least partially over the plurality of microchannels (13). The loading chamber (14) and the microchannels (13) extend substantially according to a plane identified by the substrate (11), and the microchannels (13) are partially delimited, in particular at an accumulation region thereof (CA) generally opposite to the respective inlet ends, by filtering means (17) permeable at least to air, the filtering means (17) being configured for withholding within each microchannel (13) any possible particles that may be present in the fluid sample.

    MEDICAL DEVICE FOR THE PREPARATION OF A CONCENTRATE OF CELLS
    9.
    发明申请
    MEDICAL DEVICE FOR THE PREPARATION OF A CONCENTRATE OF CELLS 审中-公开
    用于制备细胞浓度的医学装置

    公开(公告)号:WO2016067246A1

    公开(公告)日:2016-05-06

    申请号:PCT/IB2015/058361

    申请日:2015-10-29

    Applicant: ELTEK S.P.A.

    Abstract: A medical device for the separation of a concentrate enriched with cells from a biological fluid, in particular a concentrate of stromal or stem cells from medullar aspirate or venous blood, comprises: - a treatment container (3) for receiving and treating the biological fluid for the purposes of its separation into a number of fractions; - a first collection container (4), for receiving a first fraction of the fluid, in particular a fraction poor in said cells; - a second collection container (5), for receiving a second concentrated fraction of the fluid enriched with said cells; - a deviator valve (7) having a first way connected or prearranged for connection to the treatment container (3), a second way connected or prearranged for connection to the first collection container (4), and a third way connected or prearranged for connection to the second collection container (5); - a first line (10a) for connection of the treatment container (3) to the first way of the deviator valve (7), a second line (4a) for connection of the first collection container (4) to the second way of the deviator valve (7), and a third line for connection of the second collection container (5) with the third way of the deviator valve (7). The treatment container (3) is a syringe container with a plunger having a plunger stem (3c) associated in a releasable way to a corresponding plunger head, and the first connection line comprises a first transparent tube (10a), in particular a flexible transparent tube, and at least one of the second and third connection lines preferably comprises a second flexible tube (4a). At least one connection line, or each connection line, further comprises: at least one respective hydraulic connector (11, 13), for separable connection of a corresponding tube (10a, 4a) to the corresponding container (3, 4, 5) and/or to the corresponding way (7b, 7c, 7d) of the deviator valve (7); and at least one automatic-closing or one-way valve (12, 14a, 14b).

    Abstract translation: 用于从富含细胞的生物液体,特别是髓质或干细胞的基质或干细胞的浓缩物分离浓缩物的医疗装置包括: - 用于接收和处理生物流体的处理容器(3) 将其分离成若干分数的目的; - 第一收集容器(4),用于接收所述流体的第一部分,特别是所述细胞中较差的部分; - 第二收集容器(5),用于接收富集所述细胞的流体的第二浓缩级分; - 偏转阀(7),其具有连接或预定列以连接到处理容器(3)的第一路径,连接或预先布置以用于连接到第一收集容器(4)的第二路,以及连接或预定义用于连接的第三路 到第二收集容器(5); - 用于将处理容器(3)连接到偏离阀(7)的第一路的第一管线(10a),用于将第一收集容器(4)连接到第二回路 偏转阀(7)和用于将第二收集容器(5)与偏离阀(7)的第三路连接的第三管线。 处理容器(3)是具有柱塞的注射器容器,柱塞具有以可释放的方式与相应的柱塞头相关联的柱塞杆(3c),并且第一连接线包括第一透明管(10a),特别是柔性透明 并且第二和第三连接线中的至少一个优选地包括第二柔性管(4a)。 至少一个连接线或每个连接线还包括:至少一个相应的液压连接器(11,13),用于将相应的管(10a,4a)可分离地连接到相应的容器(3,4,5)和 /或偏转阀(7)的相应方式(7b,7c,7d); 和至少一个自动关闭或单向阀(12,14a,14b)。

    WASHING AGENT DISPENSER FOR DISHWASHING MACHINES

    公开(公告)号:WO2021245620A1

    公开(公告)日:2021-12-09

    申请号:PCT/IB2021/054922

    申请日:2021-06-04

    Applicant: ELTEK S.P.A.

    Abstract: A washing agent dispenser for washing machines has a dispenser body that comprises a fixed dispenser part (200), designed for mounting on a wall delimiting a washing machine wash-chamber (3), and a removable dispenser part (100), couplable in a removable way to the fixed dispenser part (200). The removable dispenser part comprises a hollow body defining at least one tank for a substance in liquid or semi solid form, at least one first wall of the hollow body being intended to face at least partially at least one second wall of the fixed dispenser part (200). The dispenser (10) also comprises at least one sensor device (270), configured to provide at least one electrical signal representative of at least one of a level and a qualitative characteristic of the substance contained within the at least one tank. The at least one sensor device (270) is arranged at least partly on the fixed dispenser part (200).

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