公开(公告)号：WO2016182624A1

公开(公告)日：2016-11-17

申请号：PCT/US2016/021698

申请日：2016-03-10

Applicant: EMD MILLIPORE CORPORATION

Inventor： ALMASIAN, Joseph M. ,  CHISHOLM, Mark E. ,  GAGNE, George A., Jr. ,  SZYK, Martin

IPC: A61F2/00

CPC classification number: B01D63/082 ,  B01D63/14 ,  B01D69/10 ,  B01D2313/025 ,  B01D2313/04 ,  B01D2319/04 ,  C02F1/001 ,  C02F2103/003 ,  C02F2103/343 ,  C02F2201/002 ,  C02F2203/006 ,  C02F2301/04 ,  C02F2303/04

Abstract: A membrane-based separation device comprises multiple interconnected flat sheets of membrane bonded to a flexible film. The bonded films are bonded in a way to create an accordion or zig-zag shape. In certain embodiments, the first or upstream layer is affixed to a suitable housing, and the last or most downstream layer is also affixed to the suitable housing. The housing may contain an inlet port for the introduction of sample, and an outlet port for the removal of filtered sample. Flow through the segments is in parallel. Since the membranes are not folded or pleated, higher performance membranes (e.g., polysulfone based membranes with some degree of asymmetry) than those usable in pleated or folded systems can be used.

Abstract translation: 膜分离装置包括多个互连的膜片，其粘合到柔性膜。 粘结薄膜以形成手风琴或曲折形状的方式粘结。 在某些实施例中，第一或上游层被固定到合适的壳体上，并且最后的或最下游的层也被固定到合适的壳体上。 壳体可以包含用于引入样品的入口端口和用于去除过滤样品的出口。 流经段是并行的。 由于膜不折叠或打褶，所以可以使用比用于打褶或折叠系统的膜更高性能的膜（例如，具有一定程度的不对称性的聚砜基膜）。

公开(公告)号：WO2018075142A1

公开(公告)日：2018-04-26

申请号：PCT/US2017/049075

申请日：2017-08-29

Applicant: EMD MILLIPORE CORPORATION

Inventor： GERINGER, Joseph ,  CASTRO, Robert ,  SZYK, Martin ,  DAUDENARDE, Sophie ,  ALMASIAN, Joseph

IPC: B01D46/00 ,  B01D35/00 ,  B65D59/06

Abstract: Port protection device particularly suited for an encapsulated filter unit. In certain embodiments, the protection device comprises a main body defining an internal region configured to receive a port or the like protruding from an encapsulated filter. In certain embodiments, the main body includes a slot that allows for easy removal of the protection device from the port or the like. A tube management system may be provided to receive and hold tubing. One suitable tube management system includes two spaced tangs that extend from the main body of the protection device and are configured to cooperatively receive and hold tubing between them.

Abstract translation:

端口保护装置，特别适用于封装式过滤单元。 在某些实施例中，保护装置包括限定内部区域的主体，该内部区域被配置为接收从封装过滤器突出的端口等。 在某些实施例中，主体包括狭槽，该狭槽允许从端口等容易地移除保护装置。 管道管理系统可以被提供以接收和保持管道。 一种合适的管子管理系统包括两个从保护装置的主体延伸的间隔开的柄脚，并且构造成协作地接收和保持它们之间的管。

公开(公告)号：WO2016109230A3

公开(公告)日：2016-07-07

申请号：PCT/US2015/066348

申请日：2015-12-17

Applicant: EMD MILLIPORE CORPORATION

Inventor： HUNT, Stephen G. ,  LANDRY, Nicholas ,  SZYK, Martin

IPC: G01N15/08 ,  B01D65/10 ,  G01F1/36

Abstract: The present disclosure relates to a filter capsule that supports direct integrity testing of an internal filter element. The filter capsule includes a filter housing having an inlet port, an outlet port, a passage running longitudinally between the inlet port and outlet port and holding a filter element, and an aseptic vent assembly. The filter housing also includes an integrity test assembly that can be used as a direct connection for integrity testing hardware, as opposed to upstream of the filter capsule. In one embodiment, the integrity test assembly comprises a body having a bore formed through its interior and a movable plunger within the bore. The plunger includes a handle to move the plunger between a closed position and an open position. Various seals between the plunger and the bore form a fluid tight seal between various portions of the plunger and the bore.