-
公开(公告)号：WO2015069739A1
公开(公告)日：2015-05-14
申请号：PCT/US2014/064088
申请日：2014-11-05
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , BARNES, Jason , MEALEY, Dane , PRESZ, Walter M. Jr , KOWALSKI, Stanley, III , MASI, Louis , KENNEDY, Thomas J., III , MCCARTHY, Brian , ROSS-JOHNSRUD, Ben
CPC classification number: C12M47/02 , A61M1/3678 , B01D21/0045 , B01D21/283 , B06B1/06 , C12M33/08 , C12M47/10
Abstract: An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a fluid.
Abstract translation: 公开了一种由模块化部件组成的消声器。 本文公开了多个模块，包括超声换能器模块，输入/输出模块，收集井模块和各种连接器模块。 这些允许构建具有用于从流体分离颗粒（例如生物细胞）的适当流体动力学的不同系统。
-
公开(公告)号：WO2016205744A1
公开(公告)日：2016-12-22
申请号：PCT/US2016/038233
申请日：2016-06-17
Applicant: FLODESIGN SONICS, INC.
Inventor： BARNES, Jason , MEALEY, Dane , KING, Jeffrey
CPC classification number: G01N21/532 , G01N1/2035 , G01N21/05 , G01N2201/06153
Abstract: Systems and methods for increasing the accuracy of a turbidity sensor are disclosed. The systems include a turbidity sensor and a flow module with a specialized flow path, with the turbidity sensor engaging with the flow module such that a measurement zone of the turbidity sensor is disposed within a flow path of the flow module and a bypass path of the flow module does not pass through the measurement zone. The methods include flowing a fluid containing bubbles into a system that separates the fluid in the flow module into a first stream of fluid containing relatively more bubbles and a second stream of fluid containing relatively fewer bubbles, the first stream flowing through a bypass path that does not pass through the measurement zone, and the second stream flowing through the measurement zone of the turbidity sensor.
Abstract translation: 公开了用于提高浊度传感器精度的系统和方法。 该系统包括浊度传感器和具有专门流路的流动模块，浊度传感器与流动模块接合，使得浊度传感器的测量区域设置在流动模块的流动路径内，并且旁路路径 流量模块不通过测量区域。 所述方法包括将含有气泡的流体流入将流动模块中的流体分离成包含相对较多气泡的第一流体流和含有相对较少气泡的第二流体流的系统中，第一流流过旁路路径， 不通过测量区，第二条流通过浊度传感器的测量区。
-
3.发明申请
公开(公告)号：WO2017189435A1
公开(公告)日：2017-11-02
申请号：PCT/US2017/029145
申请日：2017-04-24
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , MUSIAK, Ronald , MEALEY, Dane , SHAJII, Ali
CPC classification number: B01D21/283 , B06B1/0261 , B06B1/0644 , C02F1/36 , C02F1/40
Abstract: Aspects of the disclosure are directed to an apparatus for separating a second fluid or a particulate from a host fluid. That apparatus comprises a flow chamber with at least one inlet and at least one outlet. A drive circuit configured to provide a drive signal to a filter circuit configured to receive the drive signal and provide a translated drive signal. An ultrasonic transducer is cooperatively arranged with the flow chamber, and transducer includes at least one piezoelectric element configured to be driven by the current drive signal to create an acoustic standing wave in the flow chamber. At least one reflector opposing the ultrasonic transducer to reflect acoustic energy.
Abstract translation: 本公开的方面涉及一种用于从主流体分离第二流体或颗粒的装置。 该设备包括具有至少一个入口和至少一个出口的流动室。 驱动电路被配置为向被配置为接收驱动信号并提供经转换的驱动信号的滤波器电路提供驱动信号。 超声换能器与流动室协作地布置，并且换能器包括至少一个压电元件，该至少一个压电元件被配置为由电流驱动信号驱动以在流动室中产生声驻波。 至少有一个反射镜与超声波换能器相对，以反射声能。
-
公开(公告)号：WO2016054192A1
公开(公告)日：2016-04-07
申请号：PCT/US2015/053200
申请日：2015-09-30
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , KING, Jeff , SOKOLOWSKI, David , MASI, Anthony B. , KENNEDY, Brian T. , MCCARTHY, Brian , ROSS-JOHNSRUD, Benjamin , DIONNE, Jason , MEALEY, Dane , BARNES, Jason
CPC classification number: B01D21/283 , B01D17/044 , B01D17/06 , B01D19/0078 , B06B1/06 , B06B1/0622 , B06B1/0644 , B06B2201/71 , C12M47/04 , C12N13/00
Abstract: Acoustophoretic devices for separating particles from a non-flowing host fluid are disclosed. The devices include a substantially acoustically transparent container and a separation unit, with the container being placed within the separation unit. An ultrasonic transducer in the separation unit creates a planar or multi-dimensional acoustic standing wave within the container, trapping particles disposed within the non-flowing fluid and causing them to coalesce or agglomerate, then separate due to buoyancy or gravity forces.
Abstract translation: 公开了用于从非流动主流体分离颗粒的声学装置。 这些装置包括基本上声透明的容器和分离单元，容器被放置在分离单元内。 分离单元中的超声波换能器在容器内产生平面或多维声驻波，捕获设置在非流动流体内的颗粒，并使其聚结或附聚，然后由于浮力或重力而分离。
-
公开(公告)号：WO2018232045A1
公开(公告)日：2018-12-20
申请号：PCT/US2018/037420
申请日：2018-06-13
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , MUSIAK, Ronald , MEALEY, Dane , ARTIS, John , SHAJII, Ali
Abstract: An acoustic standing wave is utilized to separate components from a multi- component fluid, such as oil from an oil-water mixture, or cells entrained in a fluid, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allow for trapping of the oil as the oil coalesces, agglomerates, and becomes more buoyant than the water. A driver and controller for the acoustophoretic device accommodate variable loading as the components are separated, thereby improving separation efficiency.
-
Patent Agency Ranking
公开(公告)号：WO2018204897A1
公开(公告)日：2018-11-08
申请号：PCT/US2018/031267
申请日：2018-05-04
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , MUSIAK, Ronald , MEALEY, Dane , ARTIS, John
Abstract: An RF driver provides power to an acoustic transducer, which can be implemented as a piezoelectric element, which presents a reactive load. The driver can be a linear amplifier or a combination of a DC-DC converter and DC-AC inverter. A controller implements a control technique for efficient transducer operation. The control technique can locate a frequency for operation that is at a reactance minimum or maximum for the transducer to provide efficient operation of that transducer. An implementation of the controller can be provided in modular hardware.
-
公开(公告)号：WO2017008066A1
公开(公告)日：2017-01-12
申请号：PCT/US2016/041664
申请日：2016-07-09
Applicant: FLODESIGN SONICS, INC
Inventor： LIPKENS, Bart , PRESZ, Walter, M., Jr. , CHITALE, Kedar , KENNEDY, Thomas, J., III , GILMANSHIN, Rudolf , MEALEY, Dane , DUTRA, Brian , SOKOLOWSKI, David
CPC classification number: B06B1/0238 , B01D21/0009 , B01D21/283 , B06B1/0644 , B06B3/04 , C12M47/02 , H03H9/17
Abstract: An acoustophoretic device is disclosed. The acoustophoretic device includes an acoustic chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer includes a piezoelectric material driven by a voltage signal to create a multi-dimensional acoustic standing wave in the acoustic chamber emanating from a non-planar face of the piezoelectric material. A method for separating a second fluid or a particulate from a host fluid is also disclosed. The method includes flowing the mixture through an acoustophoretic device. A voltage signal is sent to drive the ultrasonic transducer to create the multi-dimensional acoustic standing wave in the acoustic chamber such that the second fluid or particulate is continuously trapped in the standing wave, and then agglomerates, aggregates, clumps, or coalesces together, and subsequently rises or settles out of the host fluid due to buoyancy or gravity forces, and exits the acoustic chamber.
Abstract translation: 公开了一种声学设备。 声学设备包括声学室，超声换能器和反射器。 超声波换能器包括由电压信号驱动的压电材料，以在从压电材料的非平面发出的声室中产生多维声驻波。 还公开了一种用于从主体流体分离第二流体或颗粒的方法。 该方法包括使混合物流过声波装置。 发送电压信号以驱动超声波换能器以在声学室中产生多维声驻波，使得第二流体或颗粒被连续地捕获在驻波中，然后聚集，聚集，聚集或聚结在一起， 并随后由于浮力或重力而升高或沉降在主流体之外，并离开声室。
-
公开(公告)号：WO2017161384A1
公开(公告)日：2017-09-21
申请号：PCT/US2017/025108
申请日：2017-03-30
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , KENNEDY, Thomas J., III , KING, Jeffrey , BARNES, Jason , MCCARTHY, Brian , MEALEY, Dane , MILLER, Erik , PRESZ, Walter M., Jr. , ROSS-JOHNSRUD, Benjamin , ROZEMBERSKY, John
Abstract: Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the multi-stage acoustophoretic devices are also disclosed. The systems include multiple acoustophoretic devices fluidly connected to one another in series, each acoustophoretic device comprising a flow chamber, an ultrasonic transducer capable of creating a multi-dimensional acoustic standing wave, and a reflector. The systems can further include pumps and flowmeters.
Abstract translation: 公开了用于从宿主流体中连续分离第二流体或微粒的多级声泳装置。 还公开了操作多级声泳装置的方法。 该系统包括多个彼此串联流体连接的声泳装置，每个声泳装置包括流动室，能够产生多维声驻波的超声换能器和反射器。 该系统还可以包括泵和流量计。
-
公开(公告)号：WO2017040325A1
公开(公告)日：2017-03-09
申请号：PCT/US2016/049088
申请日：2016-08-26
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , PRESZ JR, Walter M. , KING, Jeffrey , BARNES, Jason , MEALEY, Dane , MCCARTHY, Brian , ROSS-JOHNSRUD, Benjamin , CHITALE, Kedar
CPC classification number: B01D21/283 , A61M1/3678 , B06B1/0622 , G10K15/00
Abstract: Devices (100) for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber (107), a fluid outlet at a top end of the acoustic chamber (114), a concentrate outlet at a bottom end of the acoustic chamber (116), and an inlet (112) on a first side end (122) of the acoustic chamber (107). An ultrasonic transducer (106) on a side wall of the acoustic chamber and reflector at the opposite side wall create a multi-dimensional acoustic standing wave in the acoustic chamber (107) that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet (114), and the particulates are collected via the concentrate outlet (116). The device is a large-scale device that is able to process liters/hour, and has a large interior volume.
Abstract translation: 公开了用于将主流体与第二流体或颗粒分离的装置（100）。 这些装置包括声室（107），在声室（114）的顶端处的流体出口，在声室（116）的底端处的浓缩物出口，以及在第一侧 声室（107）的端部（122）。 声腔室的侧壁上的超声波换能器（106）和相对侧壁处的反射器在声室（107）中形成多个立体声波驻波，其将微粒（例如电池）与主流体捕获并分离。 主流体经由流体出口（114）收集，并且经由浓缩物出口（116）收集微粒。 该装置是能够处理升/小时，并具有大的内部容积的大型装置。
-
公开(公告)号：WO2016004398A2
公开(公告)日：2016-01-07
申请号：PCT/US2015/039125
申请日：2015-07-02
Applicant: FLODESIGN SONICS, INC.
Inventor： LIPKENS, Bart , MCCARTHY, Brian , BARNES, Jason , MEALEY, Dane , ROSS-JOHNSRUD, Ben , PRESZ JR, Walter M. , CHITALE, Kedar
IPC: C02F1/36
CPC classification number: B01D21/283 , B01D21/0045
Abstract: An acoustophoresis device which includes a substantially vertical flow path of the fluid mixture in order to improve separation of particles / secondary fluid from a primary fluid is disclosed. The vertical flow path reduces velocity non-uniformities in the acoustic chamber resulting from gravity forces. The device includes an acoustic chamber in which multidimensional acoustic standing waves are generated. The fluid can be introduced into the acoustic chamber using a dump diffuser in which a plurality of inlets enter near the bottom of the acoustic chamber such that flow symmetry reduces both, gravity driven flow non-uniformities, and any flow interference effects between inlet mixture flow into the acoustic chamber and the continuous gravity driven particle cluster drop out.
Abstract translation: 为了改善颗粒/次级流体与主流体的分离，公开了一种包括流体混合物的基本上垂直的流动路径的声波传导装置。 垂直流动路径减小了由重力引起的声室中的速度不均匀性。 该装置包括其中产生多维声驻波的声室。 可以使用倾倒扩散器将流体引入声学腔室，其中多个入口进入声学腔室的底部附近，使得流动对称性降低重力驱动的流动不均匀性和入口混合物流动之间的任何流动干涉效应 进入声室并且连续重力驱动的粒子簇脱落。
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.019 seconds)
