公开(公告)号：WO2014182394A1

公开(公告)日：2014-11-13

申请号：PCT/US2014/032835

申请日：2014-04-03

Applicant: GENERAL ELECTRIC COMPANY

Inventor： LEE, Yongjae ,  OBI, Aghogho, Atemu ,  KIM, Seog, Tae ,  PLATT, William, Chester ,  BRAY, James, William ,  PLOTNIKOV, Yuri, Alexeyevich ,  WEBSTER, Jack, Mathew ,  NECULAES, Vasile, Bogdan

IPC: G01N22/00 ,  G01N33/02

CPC classification number: G01N33/02 ,  G01N22/00 ,  G01N22/04

Abstract: A system for measuring nutritional parameters of food items is provided. The system includes a holding cavity. The system further includes a sensor assembly that includes a transmitter antenna and at least one receiver antenna. The transmitter antenna is configured to transmit signals to a food item in the holding cavity. The receiver antenna is configured to receive response signals from the food item. The system includes at least one switch coupled to each antenna. The switch, in a first state, is configured to set the sensor assembly to an electric potential equal to that of the holding cavity. In a second state, the switch is configured to couple the sensor assembly to a power source. The system also includes a processing unit to process the signals received to determine the nutritional parameters of the food item.

Abstract translation: 提供了一种用于测量食品营养参数的系统。 该系统包括一个保持腔。 该系统还包括传感器组件，其包括发射器天线和至少一个接收器天线。 发射机天线被配置为将信号发送到保持腔中的食物。 接收器天线被配置为从食品接收响应信号。 该系统包括耦合到每个天线的至少一个开关。 在第一状态下的开关被配置成将传感器组件设置成等于保持腔的电位。 在第二状态下，开关被配置成将传感器组件耦合到电源。 该系统还包括处理单元，用于处理所接收的信号以确定食品的营养参数。

公开(公告)号：WO2015112333A1

公开(公告)日：2015-07-30

申请号：PCT/US2015/010429

申请日：2015-01-07

Applicant: GENERAL ELECTRIC COMPANY

Inventor： HAY, Bruce, Allan ,  WEBSTER, Jack, Mathew

IPC: A61K51/04

CPC classification number: A61K51/0446 ,  A61K49/0004 ,  A61K51/0406 ,  C07B59/00 ,  G01N33/5091

Abstract: Imaging agents are described that comprise labeled substrates capable of being introduced into cells via the cystine/glutamate antiporter. The substrates may be used for imaging or detecting oxidative stress in cells by introducing the labeled agents into cells via the cystine/glutamate antiporter and subsequent detection.

Abstract translation: 描述了包含能够通过胱氨酸/谷氨酸反向转运体引入细胞的标记底物的成像剂。 通过将标记的试剂通过胱氨酸/谷氨酸反转录酶引入细胞并随后检测，底物可用于成像或检测细胞中的氧化应激。

公开(公告)号：WO2010125068A2

公开(公告)日：2010-11-04

申请号：PCT/EP2010/055629

申请日：2010-04-27

Applicant: GENERAL ELECTRIC COMPANY ,  GE HEALTHCARE LIMITED ,  SYUD, Faisal, Ahmed ,  LEE, Brian, Duh-Lan ,  SCHAFFER, Paul ,  ZHANG, Rong ,  WEBSTER, Jack, Mathew ,  HUNTINGTON, Jennifer ,  AMARASINGHE, Kande, Kankanamalage, Dayara

Inventor： SYUD, Faisal, Ahmed ,  LEE, Brian, Duh-Lan ,  SCHAFFER, Paul ,  ZHANG, Rong ,  WEBSTER, Jack, Mathew ,  HUNTINGTON, Jennifer ,  AMARASINGHE, Kande, Kankanamalage, Dayara

IPC: A61K49/00 ,  A61K51/04 ,  C07B59/00 ,  C07C323/58

CPC classification number: A61K51/0406 ,  A61K49/0019 ,  A61K49/0052 ,  C07B59/001 ,  C07B2200/05 ,  C07C323/58 ,  C07C323/59 ,  C07F5/022

Abstract: Imaging agents that comprise labeled substrates of the cystine/glutamate antiporter of cells, whereby the methods of use comprise introducing the labeled agents into cells via the cystine/glutamate antiporter, which are then reduced to a labeled cysteine, and subsequently detected in the cell.

Abstract translation: 包含细胞的胱氨酸/谷氨酸反转录酶的标记底物的成像剂，其中使用的方法包括将经标记的试剂通过胱氨酸/谷氨酸反转运体引入细胞，然后将其还原成标记的半胱氨酸，随后在细胞中检测。