HIGH SHEAR APPLICATION IN MEDICAL THERAPY
    1.
    发明申请
    HIGH SHEAR APPLICATION IN MEDICAL THERAPY 审中-公开
    医疗治疗中的高剪切应用

    公开(公告)号:WO2011139478A2

    公开(公告)日:2011-11-10

    申请号:PCT/US2011/031725

    申请日:2011-04-08

    Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 μm. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof; a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.

    Abstract translation: 在本公开中,描述了一种方法,其中所述方法包括在高剪切装置中混合治疗气体或治疗液体或其组合和液体载体以产生分散体; 并将产生的分散体静脉内施用于患者; 其中所制备的分散体含有平均直径小于约1.5μm的治疗液体的治疗气体或液滴的纳米气泡。 在本公开中,还描述了一种系统,其中系统包括治疗气体源或治疗液体源或其组合; 液体载体源; 具有入口,出口,至少一个转子和由剪切间隔分开的至少一个定子的高剪切装置(HSD); 以及构造成控制通过高剪切装置的流体的流速和停留时间的泵。

    SYSTEM AND PROCESS FOR INHIBITOR INJECTION
    5.
    发明申请
    SYSTEM AND PROCESS FOR INHIBITOR INJECTION 审中-公开
    用于抑制剂注射的系统和方法

    公开(公告)号:WO2009003023A2

    公开(公告)日:2008-12-31

    申请号:PCT/US2008/068163

    申请日:2008-06-25

    Abstract: A method for introducing inhibitor into a fluid to be treated by forming a dispersion comprising droplets, particles, or gas bubbles of the inhibitor dispersed in a continuous phase of a carrier, wherein the droplets, particles, or gas bubbles have a mean diameter of less than 5 microns, and wherein either the carrier is the fluid to be treated or the method further comprises introducing the dispersion into the fluid to be treated. A system for inhibiting an undesirable component, the system comprising at least one high shear mixing device comprising at least one generator comprising a rotor and a stator separated by a shear gap, wherein the high shear mixing device is capable of producing a tip speed of the rotor of greater than 22.9 m/s, and a pump for delivering a mixture of a carrier and an inhibitor to the high shear mixing device.

    Abstract translation: 通过形成包含分散在载体的连续相中的抑制剂的液滴,颗粒或气泡的分散体将抑制剂引入待处理流体的方法,其中液滴,颗粒或气泡具有较小的平均直径 超过5微米,并且其中载体是待处理的流体,或者该方法还包括将分散体引入待处理的流体中。 一种用于抑制不期望的组分的系统,所述系统包括至少一个高剪切混合装置,其包括至少一个发电机,所述至少一个发电机包括转子和由剪切间隙隔开的定子,其中所述高剪切混合装置能够产生所述高剪切混合装置的尖端速度 转子大于22.9m / s,以及用于将载体和抑制剂的混合物输送到高剪切混合装置的泵。

    SYSTEM AND PROCESS FOR PRODUCTION OF BENZOIC ACIDS AND PHTHALIC ACIDS
    8.
    发明申请
    SYSTEM AND PROCESS FOR PRODUCTION OF BENZOIC ACIDS AND PHTHALIC ACIDS 审中-公开
    苯甲酸和邻苯二甲酸的制备及方法

    公开(公告)号:WO2009002733A1

    公开(公告)日:2008-12-31

    申请号:PCT/US2008/066905

    申请日:2008-06-13

    Abstract: A method for producing benzoic acid or a methylbenzoic acid isomer is disclosed which comprises forming a dispersion comprising oxygen-containing gas bubbles dispersed in either toluene or an xylene isomer, wherein the bubbles have a mean diameter less than 1 micron. The dispersion is then subjected to reaction conditions comprising a pressure of less than about 1013 kPa and a temperature of less than about 160°C, whereby at least a portion of the toluene or xylene isomer is partially oxidized to form benzoic acid or the corresponding methylbenzoic acid isomer, respectively. In some embodiments, the methylbenzoic acid isomer is an intermediate compound, and the method further includes subjecting any unreacted xylene isomer and the intermediate compound to further oxidization, to form 1,2-benzenedicarboxylic acid, 1,3-benzenedicarboxylic acid, or 1,4-benzenedicarboxylic acid. A system or apparatus for performing the method is also disclosed.

    Abstract translation: 公开了一种生产苯甲酸或甲基苯甲酸异构体的方法,其包括形成分散在甲苯或二甲苯异构体中的含氧气泡的分散体,其中气泡的平均直径小于1微米。 然后将分散体进行包括小于约1013kPa的压力和小于约160℃的温度的反应条件,由此甲苯或二甲苯异构体的至少一部分被部分氧化以形成苯甲酸或相应的甲基苯甲酸 酸异构体。 在一些实施方案中,甲基苯甲酸异构体是中间体化合物,该方法还包括使任何未反应的二甲苯异构体和中间体化合物进一步氧化,形成1,2-苯二甲酸,1,3-苯二甲酸或1, 4-苯二甲酸。 还公开了一种用于执行该方法的系统或装置。

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