公开(公告)号：WO2011024159A3

公开(公告)日：2011-04-21

申请号：PCT/IL2010000683

申请日：2010-08-22

Applicant: HOF REFAEL ,  PEREVALOV VALERY

Inventor： HOF REFAEL ,  PEREVALOV VALERY

IPC: A61F7/00 ,  A61F7/02 ,  A61F7/03

CPC classification number: A61F2/94 ,  A61B18/04 ,  A61F2/02 ,  A61F2/04 ,  A61F2/91 ,  A61F7/12 ,  A61F2007/0292 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0066 ,  A61F2210/008 ,  A61F2250/0001 ,  A61F2250/0067 ,  A61N1/086 ,  A61N1/406 ,  A61N2007/0039

Abstract: Apparatus and methods are described for killing cancer cells (44) of a subject, the subject having cancer cells and healthy cells. The apparatus includes a plurality of first molecules (40) configured to be coupled to the cancer cells to a greater extent than to the healthy cells, in response to being administered to the subject. A plurality of clusters (42) of phase-change molecules are provided, each of the clusters coupled to a respective one of the first molecules. An energy transmission unit (50) kills cancer cells coupled to the first molecules by heating the cancer cells, by transmitting energy toward the clusters that selectively heats the clusters. Other embodiments are also described.

Abstract translation: 描述了用于杀死受试者的癌细胞（44）的装置和方法，受试者具有癌细胞和健康细胞。 该装置包括多个第一分子（40），其被配置为响应于施用于受试者而以比健康细胞更大的程度耦合到癌细胞。 提供了多个相变分子簇（42），每个簇耦合到相应的第一分子之一。 能量传输单元（50）通过加热癌细胞来杀死与第一分子偶联的癌细胞，通过向选择性加热簇的簇发射能量。 还描述了其它实施例。

公开(公告)号：WO2010150125A3

公开(公告)日：2011-03-31

申请号：PCT/IB2010052584

申请日：2010-06-10

Applicant: REDENT NOVA LTD ,  HOF REFAEL

Inventor： HOF REFAEL

IPC: A61C1/00

CPC classification number: A61C1/185 ,  A61C1/003 ,  A61C1/07 ,  A61C1/12 ,  A61C5/40

Abstract: A dental tool displacement apparatus for use with a motorized power handle to displace a dental tool includes a tool holder having a receptacle for receiving the dental tool, and a drive arrangement. The drive arrangement defines a transmission from the motorized power handle to the tool holder such that the tool holder undergoes reciprocating motion parallel to the tool axis at a first frequency of oscillations per minute and rotates about the tool axis at a second frequency of rotations per minute. In some cases, the two types of motion are generated by an eccentric drive pin engaging an annular slot which has gear teeth along one side, thereby generating an angular rotation step of the tool holder during each reciprocating stroke. In some cases, the first frequency is at least one order of magnitude greater than the second frequency.

Abstract translation: 一种用于与电动动力手柄一起用于移位牙科工具的牙科工具置换装置包括具有用于接收牙科工具的容器的工具夹具和驱动装置。 驱动装置限定了从电动动力手柄到工具架的传动，使得工具架以每分钟振荡的第一频率平行于工具轴线进行往复运动，并以每分钟转动的第二频率绕工具轴线旋转 。 在一些情况下，两种类型的运动是由偏心驱动销产生的，偏心驱动销与环形槽相啮合，环形槽沿着一侧具有齿轮齿，从而在每个往复冲程期间产生工具架的角度旋转步骤。 在一些情况下，第一频率比第二频率至少大一个数量级。