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    BINDING ASSAY DEVICE WITH RESERVOIR
    1.
    发明申请
    BINDING ASSAY DEVICE WITH RESERVOIR 审中-公开

    公开(公告)号：WO2005116185A3

    公开(公告)日：2005-12-08

    申请号：PCT/US2005/017240

    申请日：2005-05-17

    Applicant: IMMUNETICS, INC. ,  LEVIN, Andrew, E. ,  PHINNEY, Kurt

    Inventor： LEVIN, Andrew, E. ,  PHINNEY, Kurt

    IPC: G01N33/00 ,  G01N15/06 ,  G01N33/566 ,  B32B5/02 ,  C12M1/00 ,  C12M1/36 ,  C12M3/00 ,  C12M1/34

    Abstract: A binding assay device can provide an array of parallel channels with reservoirs for accommodating varying volumes of liquid samples for assay. The device generally can comprise a substantially planar base and a substantially planar top plate with open channels formed in its bottom surface. One embodiment includes a removable cassette, which forms the open channels when placed between the base and top plates. Reservoirs can be formed at the ends of the open channels with closed channels extending from the reservoirs to the top surface of the top plate. Open channels or elongated grooves or sockets can be formed in the top surface of the top plate to accommodate plug-in manifolds that can be in fluid communication with the closed channels. By allowing varying volumes of liquid samples t~ be placed in the reservoirs, the device can provide improved and/or optimized binding assay reactivities and/or band intensities.

    DETECTION OF MICROBIAL NUCLEIC ACIDS
    3.
    发明申请
    DETECTION OF MICROBIAL NUCLEIC ACIDS 审中-公开
    检测微生物核酸

    公开(公告)号：WO2009135158A2

    公开(公告)日：2009-11-05

    申请号：PCT/US2009/042578

    申请日：2009-05-01

    Applicant: IMMUNETICS, INC. ,  WASHBURN, Brian, K. ,  LEVIN, Andrew, E.

    Inventor： WASHBURN, Brian, K. ,  LEVIN, Andrew, E.

    IPC: C12Q1/04 ,  C12N1/00

    CPC classification number: C12Q1/689 ,  C07K14/24 ,  C12Q1/6837 ,  C12Q2600/166

    Abstract: The present invention features, inter alia , compositions and methods useful for identifying one or more types of microorganisms, if and when present, in a sample or plurality of samples ( e.g ., in one or more samples tested in parallel). More specifically, the present compositions and methods can be used in, e.g., determining whether a subject has a microbial infection ( e.g ., a bacterial, fungal, protozoal, or viral infection), determining the identity of the microbe(s) causing the infection, and/or determining, or helping to determine, an appropriate anti-microbial treatment regimen for a subject identified as having an infection ( e.g. , an appropriate antibiotic, anti-fungal, anti-viral, or other treatment regimen).

    Abstract translation: 本发明特别地特征在于用于鉴定一种或多种类型的微生物的组合物和方法，如果和存在于样品或多个样品中（例如在一个或多个并行测试的样品中）。 更具体地，本发明的组合物和方法可以用于例如确定受试者是否具有微生物感染（例如细菌，真菌，原生动物或病毒感染），确定导致感染的微生物的身份 ，和/或确定或帮助确定被鉴定为具有感染（例如适当的抗生素，抗真菌，抗病毒或其它治疗方案）的受试者的适当的抗微生物治疗方案。

    SENSITIVE AND SPECIFIC ASSAY FOR BABESIA SPP.
    4.
    发明申请
    SENSITIVE AND SPECIFIC ASSAY FOR BABESIA SPP. 审中-公开
    BABESIA SPP的敏感和特异性测定。

    公开(公告)号：WO2013059795A1

    公开(公告)日：2013-04-25

    申请号：PCT/US2012/061333

    申请日：2012-10-22

    Applicant: IMMUNETICS, INC.

    Inventor： ERWIN, James, L. ,  KRUEGER, Neil, X. ,  LEVIN, Andrew, E.

    IPC: G01N33/569 ,  G01N33/532 ,  G01N33/543 ,  G01N33/68

    CPC classification number: G01N33/6893 ,  G01N33/56905 ,  G01N2333/44

    Abstract: The invention is directed to methods of using novel Babesia antigen peptides in detecting Babesia spp. in a sample. The methods may be adapted to assays suitable for high blood volume screening, use for clinical diagnosis of patients with babesiosis, or assaying blood contaminated with Babesia spp. , such as B. microti .

    Abstract translation: 本发明涉及使用新型巴贝虫抗原肽检测巴贝虫属（Babesia spp）的方法。 在一个样本。 所述方法可适用于适合于高血容量筛选，用于临床诊断患有巴西病的患者或测定受巴贝虫感染的血液（如微生物）的测定。

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