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公开(公告)号:WO2022150418A1
公开(公告)日:2022-07-14
申请号:PCT/US2022/011356
申请日:2022-01-06
Applicant: INSULET CORPORATION
Inventor: NAZZARO, David
Abstract: Disclosed are examples of devices, systems and techniques for delivering a liquid drug. An example delivery pump device may include a chamber body defining a pump chamber, an inlet valve to receive a liquid drug and a hard stop. A plunger configured with a plunger channel. A sliding fluidic member including a needle coupling, a flow orifice, a face seal and an anchor portion that may be movable within the pump chamber. A pump mechanism may be coupled to the anchor portion and operable to pull the anchor portion and the plunger toward the hard stop. Techniques may include determining a time to output a liquid drug from the delivery pump device; generating a control signal to actuate the delivery pump device; applying a control signal to the pump mechanism; determining that a control signal is to be removed from the pump mechanism; and delivering the liquid drug.
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公开(公告)号:WO2022146541A1
公开(公告)日:2022-07-07
申请号:PCT/US2021/057261
申请日:2021-10-29
Applicant: INSULET CORPORATION
Inventor: O'CONNOR, Jason , LEE, Joon Bok , NAZZARO, David , ZHENG, Yibin , TANDON, Pauline
Abstract: A system for automatically delivering medication to a user is disclosed. A sensor worn by the user can collect information regarding the user. A user device, for example, a smartphone, executes a user application that uses the collected information to determine an amount of medication to provide to the user. The user application includes a graphical user interface that allows the user to easily interact with the user application to specify various aspects of the delivery of the medication. The user application controls a wearable drug delivery device to dispense the medication to the user.
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公开(公告)号:WO2021163179A1
公开(公告)日:2021-08-19
申请号:PCT/US2021/017441
申请日:2021-02-10
Applicant: INSULET CORPORATION
Inventor: NAZZARO, David , CARDINALI, Steven , CONTE, Nicholas , ALLIS, Daniel , O'CONNOR, Jason , LEE, Joon Bok , ZADE, Ashutosh , HENNING, Timothy , METZMAKER, Thomas , MCLAUGHLIN, Ian
Abstract: Disclosed are examples of a device, a system, methods and computer-readable medium products operable to implement functionality to determine and respond to a purpose of a meal. An algorithm or application may receive data that may include data related to a meal purpose from data sources and determine whether any of the data received from the plurality of data sources was received from a direct data source or an indirect data source. The data may be evaluated to determine a purpose of the meal. Based on the results of the evaluation, instructions may be generated to provide an appropriate response based on the determined purpose of the meal. The generated instructions to provide the appropriate response based on the determined purpose of the meal may be output.
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公开(公告)号:WO2018136699A1
公开(公告)日:2018-07-26
申请号:PCT/US2018/014351
申请日:2018-01-19
Applicant: INSULET CORPORATION
Inventor: MCCAFFREY, Maureen , NAZZARO, David , MCLAUGHLIN, Ian , KOZIN, Simon
Abstract: Drug delivery systems with reduced hold-up volumes are provided. The drug delivery systems include a cartridge (202) configured to hold a liquid drug. A cartridge stopper (702) is positioned in a first portion of the cartridge. A needle guide component (704) is positioned within the cartridge stopper. A needle (706) is positioned within a central opening (708) of the needle guide. A plunger (714) is positioned in a second portion of the cartridge. The plunger includes a fluid path pocket (718) facing and aligned with the central opening of the needle guide component. The plunger is driven toward the cartridge stopper to expel the liquid drug from the cartridge through the needle. An end of the needle can be positioned within the fluid path pocket when the plunger is pushed against the cartridge stopper, ensuring that only a small volume of the liquid drug remains in the cartridge when delivery of the liquid drug is completed.
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公开(公告)号:WO2017091584A1
公开(公告)日:2017-06-01
申请号:PCT/US2016/063350
申请日:2016-11-22
Applicant: INSULET CORPORATION
Inventor: RIOUX, Robert , NAZZARO, David
CPC classification number: A61M5/1723 , A61M5/14 , A61M5/14216 , A61M5/14248 , A61M5/1452 , A61M5/14526 , A61M5/158 , A61M5/172 , A61M2005/14204 , A61M2005/14252 , A61M2005/14272 , A61M2005/1585 , A61M2005/1586 , A61M2205/0266 , A61M2205/0272 , A61M2205/18 , A61M2205/276 , A61M2205/3303 , A61M2205/3368 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/587 , A61M2205/8206 , A61M2230/06 , A61M2230/20 , A61M2230/201 , A61M2230/30 , A61M2230/50 , A61M2230/63
Abstract: Systems and methods for delivering a medication to a person experiencing an emergency medical event without requiring intervention or action on the part of the person. A device encases a reservoir of medication and a delivery mechanism. Sensors in the housing sense a physical attribute of the person and circuitry monitors information collected by the sensors to determine if the person is experiencing a severe medical condition or event based on the information. An input device on or in the housing, such as a button, may be used or activated by the person if the detected condition or event is a false positive to cancel further action. If the system does not include the button or if the user does not press it in time, the system activates the delivery device and injects the medication into the person.
Abstract translation: 用于将药物递送给经历紧急医疗事件的人员的系统和方法,而不需要人员的干预或采取行动。 装置包含药物储存器和递送机构。 外壳中的传感器感测人的物理属性,并且电路监测传感器收集的信息,以基于信息确定人是否正在经历严重的医疗状况或事件。 如果检测到的状况或事件是误报以取消进一步的动作,则可以使用或启动外壳上或外壳中的输入设备,例如按钮。 如果系统不包含按钮,或者用户没有及时按下按钮,系统会激活传送装置并将药物注入人体。 p>
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公开(公告)号:WO2022164710A1
公开(公告)日:2022-08-04
申请号:PCT/US2022/013139
申请日:2022-01-20
Applicant: INSULET CORPORATION
Inventor: NAZZARO, David , D'ARCO, John , CONTE, Nicholas , SUN, Kepei
IPC: A61M5/142
Abstract: In an exemplary embodiment, a drug delivery device is configured for Body Channel Communication (BCC). The drug delivery device may include a conductive element embedded in an adhesive patch that secures the drug delivery device to the user. This conductive element acts as a coupler to the body of the user. Another conductive element may also be provided at a face of the housing. This conductive element acts as the other end of the coupler formed with the conductive coil in the adhesive patch. The conductive coil in the adhesive patch conforms well to the user's skin surface and thus facilitates a good quality coupling with the user.
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7.
公开(公告)号:WO2022146715A1
公开(公告)日:2022-07-07
申请号:PCT/US2021/063914
申请日:2021-12-16
Applicant: INSULET CORPORATION
Inventor: NAZZARO, David , D'ARCO, John , CONTE, Nicholas , SUN, Kepei
Abstract: An on-body drug delivery device may have one or more antennas secured outside a housing of the on-body drug delivery device for facilitating wireless communications. The one or more antennas may be secured to an adhesive pad that adheres the on-body drug delivery device to a user. Alternatively, the one or more antennas may be secured to a portion of the housing for the on-body drug delivery device. In such instances, the one or more antennas may pass through one or more holes in the housing to facilitate an electrical connection with a component, like a wireless communications transceiver, inside the housing. Alternatively, wireless communications with the one or more antennas and the component may be used.
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公开(公告)号:WO2022072823A2
公开(公告)日:2022-04-07
申请号:PCT/US2021/053162
申请日:2021-10-01
Applicant: INSULET CORPORATION
Inventor: CARDINALI, Steven , NAZZARO, David , MCLAUGHLIN, Ian
IPC: A61M5/142 , A61M2005/1426 , A61M2005/1585 , A61M2005/1726 , A61M2205/3303 , A61M2230/201 , A61M5/14248 , A61M5/158 , A61M5/172 , A61M5/1723
Abstract: Methods and apparatuses for performing an insertion process for a plurality of penetrating elements are described. For example, a wearable fluid infusion device may include a cannula and/or needle for infusing a fluid into a patient and a sensor for sensing a physical characteristic of the patient. A non-limiting example of a fluid may be or may include insulin. An illustrative and non-restrictive example of a physical characteristic may include a blood glucose level. The wearable infusion device may be configured to facilitate insertion of the multiple penetrating elements, such as a cannula and a sensor, in a single simultaneous insertion step instead of requiring individual insertion steps for each of multiple penetrating elements. Other embodiments are described.
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公开(公告)号:WO2020018792A2
公开(公告)日:2020-01-23
申请号:PCT/US2019/042408
申请日:2019-07-18
Applicant: INSULET CORPORATION
Inventor: O'CONNOR, Jason , MCLAUGHLIN, Ian , ALLIS, Daniel , NAZZARO, David
Abstract: Disclosed are examples for a system for drug delivery and components thereof. The system may include an on-body pump device and a secondary unit. The on-body pump device may include a reservoir and a fluid pathway. The reservoir may be configured to hold a liquid drug. The secondary unit may be removably coupled to the on-body pump device. The secondary unit may be configured to receive a prefilled cartridge containing a liquid drug, expel the liquid drug from the prefilled cartridge, and deliver the liquid drug to the reservoir of the on-body pump device via the fluid pathway. Examples of variations to the secondary unit are also disclosed.
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公开(公告)号:WO2017205819A1
公开(公告)日:2017-11-30
申请号:PCT/US2017/034814
申请日:2017-05-26
Applicant: INSULET CORPORATION
Inventor: NAZZARO, David , McLAUGHLIN, Ian , KOZIN, Simon , McCAFFREY, Maureen , MAC, Jackie , DOUDOUMOPOULUS, Alexander , PATEL, Bhavin
Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.
Abstract translation: 提供了一种可以将储存在容器中的液体药物输送给患者的可佩戴的药物输送装置。 容器可以是预装药筒,其可以由患者装载到药物输送装置中,或者当被提供给患者时可以预先装载在药物输送装置内。 将容器的密封端穿刺以将储存的液体药物连接至与导管插入部件连接的针导管,所述针插入部件为患者提供通路。 药物输送装置的驱动系统可以通过针管将液体药物从药筒排出到患者。 可以控制驱动系统以向患者提供单剂量或多剂量的液体药物。 p>
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