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公开(公告)号：WO2003008033A1
公开(公告)日：2003-01-30
申请号：PCT/IL2002/000591
申请日：2002-07-18
Applicant: L.R. R & D LTD. , ROSENBERG, Lior
Inventor： ROSENBERG, Lior
IPC: A61M35/00
CPC classification number: B05C17/002 , A61B90/80 , A61B2017/320008 , A61M35/003
Abstract: Device for treating pathological conditions of skin surfaces, which comprises a main component that includes a body and a contact layer superimposed to one another, wherein the body is porous to provide storage capacity for liquid medicament fed to it and permeable for transmitting the medicament to the contact layer by compression or capillarity or both. The contact layer is also porous for transmitting the medicament received from the body to the skin surface being treated and has a mildly or strongly abrasive outer surface for removing damaged surface skin tissue. The device also comprises a delivery apparatus for feeding liquid medicament to the body of the main component and, an optional storage container for the liquid medicament.
Abstract translation: 用于治疗皮肤表面的病理状况的装置，其包括主要成分，所述主要成分包括主体和彼此重叠的接触层，其中所述主体是多孔的，以提供供给其的液体药物的储存能力，并且可渗透以将药物传输至 接触层通过压缩或毛细作用或两者兼而有之。 接触层也是多孔的，用于将从身体接收的药物传送到被治疗的皮肤表面，并且具有轻微或强烈磨蚀的外表面，用于去除损伤的表面皮肤组织。 该装置还包括用于将液体药物输送到主要部件的主体的输送装置和用于液体药物的任选的储存容器。
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公开(公告)号：WO2002058774A2
公开(公告)日：2002-08-01
申请号：PCT/IL2002/000073
申请日：2002-01-24
Applicant: L.R. R & D LTD. , ROSENBERG, Lior
Inventor： ROSENBERG, Lior
IPC: A61M25/00
CPC classification number: A61M25/02 , A61B17/3401
Abstract: Method of holding in place a transcutaneous implant by applying an adhesive in liquid form to the implant and the area of the patient's skin about the needle and allowing the adhesive to set. The implant is constituted by an infusion needle, a catheter or any transcutaneous implant. Whenever the adhesive is in liquid form, it has such a surface tension that it will flow along the implant and the skin to reach a terminal point, which is the point at which the implant is inserted. The adhesive is applied in liquid form and flows along the implant and the skin to reach the point at which the implant is inserted, and then allowed to set, to hold the implant in place.
Abstract translation: 通过将液体形式的粘合剂施加到植入物以及患者皮肤周围针的区域并允许粘合剂凝固来保持经皮植入物的方法。 植入物由输液针，导管或任何经皮植入物构成。 无论何时粘合剂为液体形式，其具有这样的表面张力，以致其将沿着植入物和皮肤流动到达终点，该终点是植入物插入的点。 粘合剂以液体形式施用，并沿着植入物和皮肤流动以达到植入物插入的位置，然后允许固定，以将植入物固定到位。
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公开(公告)号：WO2010038231A1
公开(公告)日：2010-04-08
申请号：PCT/IL2009/000946
申请日：2009-10-01
Applicant: L.R.R.& D. LTD. , ROSENBERG, Lior
Inventor： ROSENBERG, Lior
CPC classification number: A61F13/00008 , A61F13/00063 , A61F13/00991 , A61F2013/00157 , A61F2013/00165 , A61F2013/00255 , A61F2013/00285 , A61F2013/00323 , A61F2013/00519 , A61F2013/0054 , A61F2013/00634 , A61F2013/0074 , A61F2013/00748 , A61F2013/0091 , A61F2013/00927 , A61F2013/00931 , A61L15/28 , A61L15/425 , A61L15/60
Abstract: The invention relates to a wound dressing and methods of preparation and use thereof for promoting healing of a wound bed. In particular, the wound dressing is advantageous for application to a debrided wound bed. The wound dressing comprises an open conduit polymeric foam matrix, and a hydrophilic polymer which is disposed in dry form on the inner surfaces of the conduits within the matrix.
Abstract translation: 本发明涉及一种伤口敷料及其制备和使用方法，用于促进伤口床的愈合。 特别地，伤口敷料对于应用于清创伤口床是有利的。 伤口敷料包括开放导管聚合物泡沫基质和亲水性聚合物，其以干燥形式设置在基质内导管的内表面上。
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公开(公告)号：WO2004069147A2
公开(公告)日：2004-08-19
申请号：PCT/IL2004/000104
申请日：2004-02-03
Applicant: MEDIWOUND LTD. , ROSENBERG, Lior
Inventor： ROSENBERG, Lior
IPC: A61K
CPC classification number: A61B17/22004 , A61B2017/00761 , A61B2017/320004 , A61N7/00
Abstract: A device, system and method for enhancing the functionality and efficiency of a chemical and/or enzymatic debriding agent with a physical debriding mechanism. The debriding agent alone and the physical mechanism alone are each capable of at least some debriding activity separately, without being used in the combination. In combination, however, they are more effective, such that the debriding efficacy is increased for the combination. Preferably, the physical debriding mechanism comprises an ultrasound source.
Abstract translation: 一种用物理清创机制增强化学和/或酶促清除剂的功能和效率的装置，系统和方法。 单独的清创剂和单独的物理机制各自能够分开进行至少一些清创活动，而不用于组合。 然而，它们组合更有效，使得组合的清创功效增加。 优选地，物理清创机构包括超声源。
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公开(公告)号：WO2003049783A3
公开(公告)日：2003-06-19
申请号：PCT/IL2002/000878
申请日：2002-11-05
Applicant: MEDGENICS, INC. , BELLOMO, Stephen, F. , ROSENBERG, Lior , BUKHMAN, Mordechay , PEARLMAN, Andrew, L. , LIPPIN, Itzhak , SHAVITT, Menachem, D.
Inventor： BELLOMO, Stephen, F. , ROSENBERG, Lior , BUKHMAN, Mordechay , PEARLMAN, Andrew, L. , LIPPIN, Itzhak , SHAVITT, Menachem, D.
IPC: A61B10/00
Abstract: A method of harvesting a tissue sample (318) from a subject (311), comprising: attaching an outer surface of a portion of the tissue sample (318) to a substantially flat surface area; lifting the surface area, together with the portion of the tissue (318); and slicing the tissue (318) at a given distance below the surface area of said portion to separate the portion to separate the tissue portion (318) from the subject (311).
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Patent Agency Ranking
公开(公告)号：WO2003049783A2
公开(公告)日：2003-06-19
申请号：PCT/IL2002/000878
申请日：2002-11-05
Applicant: MEDGENICS, INC. , BELLOMO, Stephen, F. , ROSENBERG, Lior , BUKHMAN, Mordechay , PEARLMAN, Andrew, L. , LIPPIN, Itzhak , SHAVITT, Menachem, D.
Inventor： BELLOMO, Stephen, F. , ROSENBERG, Lior , BUKHMAN, Mordechay , PEARLMAN, Andrew, L. , LIPPIN, Itzhak , SHAVITT, Menachem, D.
IPC: A61M
CPC classification number: C12M21/08 , A61B17/322 , A61B2017/3225 , A61K35/36 , A61K38/1816 , A61K38/212 , A61K47/6901 , C12M35/08 , C12M45/02 , A61K2300/00
Abstract: A method of harvesting a tissue sample from a subject, comprising: attaching an outer surface of a portion of the tissue sample to a substantially flat surface area; lifting the surface area, together with the portion of the tissue; and slicing the tissue at a given distance below the surface area of said portion to separate the tissue portion from the subject.
Abstract translation: 从受试者收集组织样本的方法，包括：将所述组织样本的一部分的外表面附接到基本平坦的表面区域; 提起表面积与组织的一部分一起; 以及在所述部分的表面区域之下的给定距离处切片组织以将组织部分与受试者分开。
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7.发明申请METHOD AND APPARATUS FOR PRODUCTION OF A SKIN GRAFT AND THE GRAFT PRODUCED THEREBY 审中-公开用于生产皮肤牙齿的方法和装置及其生产的牙齿
公开(公告)号：WO2003049626A1
公开(公告)日：2003-06-19
申请号：PCT/IL2002/000879
申请日：2002-11-05
Applicant: MEDGENICS, INC. , BELLOMO, Stephen, F. , PEARLMAN, Andrew, L. , PIVA, Guillermo, A. , ROSENBERG, Lior , LIPPIN, Itzhak , BUKHMAN, Mordechay , SHAVITT, Menachem, D. , SHER, Niv
Inventor： BELLOMO, Stephen, F. , PEARLMAN, Andrew, L. , PIVA, Guillermo, A. , ROSENBERG, Lior , LIPPIN, Itzhak , BUKHMAN, Mordechay , SHAVITT, Menachem, D. , SHER, Niv
IPC: A61B17/322
CPC classification number: C12M21/08 , A61B17/322 , A61B2017/3225 , A61K35/36 , A61K38/1816 , A61K38/212 , A61K47/6901 , C12M35/08 , C12M45/02 , A61K2300/00
Abstract: A micro-organ structure comprising at least two micro-organ portions formed from a tissue, in which said at least two micro-organs are linked one to the other by means of a junction formed from said tissue of which the micro-organs were formed therefrom.
Abstract translation: 一种微器官结构，其包括由组织形成的至少两个微器官部分，其中所述至少两个微器官通过由形成有微器官的所述组织形成的连接点而彼此连接 由此。
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公开(公告)号：WO2003039382A2
公开(公告)日：2003-05-15
申请号：PCT/IL2002/000880
申请日：2002-11-05
Applicant: MEDGENICS, INC. , PEARLMAN, Andrew, L. , BELLOMO, Stephen, F. , GARFINKEL, Leonard, I. , PIVA, Guillermo, A. , SHAVITT, Menachem, D. , ROSENBERG, Lior , LIPPIN, Itzhak , BUKHMAN, Mordechay , ALMON, Einat , SHER, Niv
Inventor： PEARLMAN, Andrew, L. , BELLOMO, Stephen, F. , GARFINKEL, Leonard, I. , PIVA, Guillermo, A. , SHAVITT, Menachem, D. , ROSENBERG, Lior , LIPPIN, Itzhak , BUKHMAN, Mordechay , ALMON, Einat , SHER, Niv
IPC: A61B17/322
CPC classification number: C12M21/08 , A61B17/322 , A61B2017/3225 , A61K35/36 , A61K38/1816 , A61K38/212 , A61K47/6901 , C12M35/08 , C12M45/02 , A61K2300/00
Abstract: A micro-organ processing system, comprising: a plurality of operational modules, each said module performing all or part of a process of producing said micro-organ from a tissue sample; and means for transferring the tissue sample or micro-organ from one module to a next module in the process, via ports in the modules, without removal of the tissue sample from the modules.
Abstract translation: 一种微器官处理系统，包括：多个操作模块，每个所述模块执行从组织样本产生所述微器官的过程的全部或部分; 以及用于通过模块中的端口将组织样本或微器官从一个模块转移到该过程中的下一个模块的装置，而不从模块中移除组织样本。
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9.发明申请PROTEOLYTIC EXTRACT FROM BROMELAIN FOR THE TREATMENT OF CONNECTIVE TISSUE DISORDERS 审中-公开用于治疗连接性组织病的BROMELAIN的蛋白质提取物
公开(公告)号：WO2013011514A1
公开(公告)日：2013-01-24
申请号：PCT/IL2012/050261
申请日：2012-07-19
Applicant: MEDIWOUND LTD. , ROSENBERG, Lior , RUBIN, Guy , ASCULAI, Eilon
Inventor： ROSENBERG, Lior , RUBIN, Guy , ASCULAI, Eilon
CPC classification number: A61K38/4873 , A61K9/0019 , A61K9/08 , A61K9/14 , A61K36/88 , A61K38/1732 , A61K45/06 , C12Y304/22031 , C12Y304/22032 , A61K2300/00
Abstract: The present invention relates to a proteolytic extract obtained from bromelain for the treatment of connective tissue diseases. In particular, the present invention relates to a pharmaceutical composition comprising a proteolytic extract obtained from bromelain for the treatment of diseases such as Dupuytren's disease and Peyronie's disease.
Abstract translation: 本发明涉及由菠萝蛋白酶获得的用于治疗结缔组织疾病的蛋白水解提取物。 特别地，本发明涉及药物组合物，其包含从菠萝蛋白酶获得的蛋白水解提取物，用于治疗诸如Dupuytren氏病和Peyronie氏病的疾病。
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公开(公告)号：WO2006006167A2
公开(公告)日：2006-01-19
申请号：PCT/IL2005/000744
申请日：2005-07-13
Applicant: MEDIWOUND LTD. , TOREN, Amir , ROSENBERG, Lior , GORECKI, Marian
Inventor： TOREN, Amir , ROSENBERG, Lior , GORECKI, Marian
IPC: A61K38/48
CPC classification number: A61K45/06 , A61K33/38 , A61K2300/00
Abstract: The invention relates to compositions for debriding damaged skin comprising at least one enzymatic debriding agent and at least one antiseptic compound comprising heavy metal ions. The present invention further relates to kit and methods for topical debridement of damaged skin, particularly of burned skin.
Abstract translation: 本发明涉及用于清除受损皮肤的组合物，其包含至少一种酶促清除剂和至少一种包含重金属离子的防腐化合物。 本发明还涉及用于局部清创损伤的皮肤，特别是烧伤皮肤的试剂盒和方法。
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