专利检索 ap:("MALLINCKRODT LLC") AND inv:"HERMAN, Clifford J." 第 1 页

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发明申请
GLUCOMANNAN CONTAINING PHARMACEUTICAL COMPOSITIONS WITH EXTENDED RELEASE AND ABUSE DETERRENT PROPERTIES 审中-公开
标题翻译：含葡糖糖胺的药物组合物，其具有延长释放和破坏性质

公开(公告)号：WO2017139106A1

公开(公告)日：2017-08-17

申请号：PCT/US2017/015235

申请日：2017-01-27

申请人： MALLINCKRODT LLC

发明人： GOWER, Brad L. , PARK, Jae Han , HERMAN, Clifford J. , LAI, Tsz Chung , FENG, Kai

IPC分类号： A61K31/485 , A61K47/36

CPC分类号： A61K47/36 , A61K9/2013 , A61K9/2031 , A61K9/205 , A61K9/2054 , A61K31/485 , A61K47/34

摘要： A pharmaceutical composition comprising at least one active pharmaceutical ingredient (API) or a pharmaceutically acceptable salt thereof, a glucomannan, a first polyalkylene oxide having an average molecular weight of no more than 300,000, and a second polyalkylene oxide having an average molecular weight of at least 1,000,000 and methods of making. The pharmaceutical composition extended release of the API and has abuse deterrent features.

摘要翻译： 包含至少一种活性药物成分（API）或其药学上可接受的盐，葡甘露聚糖，平均分子量不超过300,000的第一聚环氧烷和第二聚亚烷基二醇的药物组合物平均分子量至少为1,000,000的氧化物和制备方法。药物组合物延长了API的释放并具有滥用威慑特征。