公开(公告)号：WO2004013735A3

公开(公告)日：2004-04-08

申请号：PCT/US0324389

申请日：2003-08-04

Applicant: VERIFICATION SECURITY CORP ,  MCGREW STEPHEN P

Inventor： MCGREW STEPHEN P

IPC: G06K7/08 ,  G06K17/00 ,  G06K19/06 ,  G06K19/12

CPC classification number: G06K7/1417 ,  G06K7/087 ,  G06K19/06187 ,  G06K19/12 ,  G06K2017/0038 ,  G07D7/04

Abstract: A system and associated method provide a marking of material to be applied to goods. In one embodiment, magnetic material is applied in a predetermined pattern. An accumulation of magnetic material in one orientation across the structured pattern may provide an automatically sensible value. Magnetically readable material may be provided as a predetermined, repeatable pattern, where the magnetic material is applied to a surface with a resolution in a range of at least 10,000 to 100 dots per inch.

Abstract translation: 系统和相关方法提供要应用于货物的材料的标记。 在一个实施例中，以预定图案施加磁性材料。 通过结构化图案的一个取向的磁性材料的累积可以提供自动合理的值。 磁性可读材料可以作为预定的可重复的图案提供，其中磁性材料以每英寸至少10,000至100点的范围内的分辨率施加到表面。

公开(公告)号：WO2010021873A3

公开(公告)日：2010-06-24

申请号：PCT/US2009053404

申请日：2009-08-11

Applicant: GENPRIME INC ,  FLEMING JAMES E ,  MCGREW JESSE M ,  MCGREW STEPHEN P ,  NICHOLES PATRICK ,  HUMPHREYS JOHNNY

Inventor： FLEMING JAMES E ,  MCGREW JESSE M ,  MCGREW STEPHEN P ,  NICHOLES PATRICK ,  HUMPHREYS JOHNNY

IPC: G01N35/00 ,  G01N30/74 ,  G06F19/00

CPC classification number: G01N21/77 ,  G01N21/8483 ,  G01N2035/00108 ,  G16H10/40 ,  G16H40/63

Abstract: An assay system includes an optical imager to acquire high resolution images of assay strips (e.g., lateral flow immunochromatographic test strips) and performs image processing to identify individual assay strips and determine results for each assay strip, by quantifies the presence or absence of test signal line(s) and control signal line(s). Assay strips may be in a holder or carrier contained in a specimen container also holding a specimen. The assay system automatically logs all results and data to a database that stores a high resolution image of the original immunochromatographic assay, the values of test line(s) and control line(s), and the test result. A user interface directs an end user through operation.

Abstract translation: 测定系统包括光学成像仪以获得测定条的高分辨率图像（例如横向流动免疫层析测试条），并执行图像处理以识别各个测定条，并通过量化测试信号的存在或不存在来确定每个测定条的结果 线路和控制信号线。 测定条可以在包含在也保持标本的样本容器中的保持器或载体中。 测定系统将所有结果和数据自动记录到存储原始免疫色谱测定的高分辨率图像，测试线和对照线的值以及测试结果的数据库。 用户界面指示最终用户通过操作。

公开(公告)号：WO2004031366A3

公开(公告)日：2004-06-10

申请号：PCT/US0331490

申请日：2003-10-02

Applicant: NEW LIGHT IND LTD ,  MCGREW STEPHEN P ,  LIGHTFOOT DONALD R

Inventor： MCGREW STEPHEN P ,  LIGHTFOOT DONALD R

IPC: B01J19/00 ,  C12N20060101 ,  C12Q1/68 ,  C40B40/06 ,  C40B50/14 ,  G01N27/26

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00385 ,  B01J2219/00432 ,  B01J2219/00434 ,  B01J2219/00439 ,  B01J2219/00497 ,  B01J2219/00518 ,  B01J2219/00527 ,  B01J2219/00538 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00653 ,  B01J2219/00657 ,  B01J2219/00659 ,  B01J2219/00675 ,  B01J2219/00677 ,  B01J2219/00704 ,  B01J2219/00711 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01L3/5085 ,  C12Q1/6825 ,  C12Q1/6837 ,  C40B40/06 ,  C40B50/14 ,  G01N33/54373 ,  C12Q2565/501 ,  C12Q2565/607 ,  C12Q2565/515

Abstract: A method for manufacturing an array of biomolecules that have complementary binding species is disclosed. The method utilizes a master substrate containing a desired master array of binding molecules or ligands, e.g., DNA target molecules. A mixture of complementary, antiligand molecules, e.g., DNA probe molecules, are then hybridized to the ligands of the master array, forming an array of antiligand molecules reversibly bound to the molecules in the master array. The antiligand array is then transferred and bound to a separate substrate, to form a desired array of antiligand molecules on the separate substrate. The process may be repeated to produce multiple arrays or multiple generations of arrays. Also disclosed is a sensor array device and method. The device includes an array of vibratory tympanic elements, each having a specific analyte binding probe carried on the vibratory membrane of the element. A binding event is detected by a change in the vibrational resonance of a selected element.

Abstract translation: 公开了一种制备具有互补结合物质的生物分子阵列的方法。 该方法利用含有所需主要结合分子主阵列或配体的母基质，例如DNA靶分子。 然后将互补的配子分子（例如DNA探针分子）的混合物与主阵列的配体杂交，形成可逆地结合到主阵列中的分子的反配体分子的阵列。 然后将反配体阵列转移并结合到单独的底物上，以在分离的底物上形成所需的抗配体分子阵列。 可以重复该过程以产生多个阵列或多代阵列。 还公开了一种传感器阵列装置和方法。 该装置包括振动鼓膜元件阵列，每个振动鼓膜元件具有承载在该元件的振动膜上的特定分析物结合探针。 通过所选元件的振动共振的变化来检测结合事件。

公开(公告)号：WO2004102259A3

公开(公告)日：2006-01-26

申请号：PCT/US2004010252

申请日：2004-03-31

Applicant: NEW LIGHT IND LTD ,  MCGREW STEPHEN P ,  CARVER SALLY-ANNE

Inventor： MCGREW STEPHEN P ,  CARVER SALLY-ANNE

IPC: B42D15/10 ,  B44F1/12 ,  G02B5/18 ,  G03H1/04 ,  G06K9/76

CPC classification number: B42D25/391 ,  B42D25/00 ,  B42D25/23 ,  B42D25/328 ,  B42D25/425 ,  G02B5/1809 ,  G02B5/1857 ,  G02B5/3083 ,  G03H1/0011 ,  G03H1/0244 ,  G03H1/028 ,  G03H1/041 ,  G03H2001/0288

Abstract: An anticounterfeiting device comprising a surface relief structure having both diffractive and polarizing properties. Polarization of reflected light is controlled by the orientation and composition of a fine grating structure whose shortest period is substantially smaller than the wavelength of visible light; and diffraction is controlled by a longer period component of the grating structure having a second orientation. Presence and arrangement of the polarizing properties of the device are detected by illuminating the device with polarized light and viewing the reflected light, or by illuminating the device with unpolarized light and viewing reflected light through a polarizer. Because such a device is difficult to copy or reverse engineer precisely, the authenticity of the device can be judged by the presence and arrangement of the polarization properties and the diffraction properties in the device.

Abstract translation: 一种防伪装置，包括具有衍射和偏振性质的表面浮雕结构。 反射光的极化由最短周期远小于可见光波长的精细光栅结构的取向和组成来控制; 并且衍射由具有第二取向的光栅结构的较长周期分量控制。 通过用偏振光照射装置并观察反射光，或通过用非偏振光照亮装置并通过偏振器观察反射光来检测装置的偏振特性的存在和排列。 由于这样的装置难以精确地复制或逆向工程，所以可以通过设备中的偏振特性和衍射特性的存在和布置来判断装置的真实性。

公开(公告)号：WO9201973A3

公开(公告)日：1992-03-19

申请号：PCT/US9105085

申请日：1991-07-18

Applicant: MCGREW STEPHEN P

Inventor： MCGREW STEPHEN P

IPC: G03F7/00 ,  G03H1/02 ,  G03H1/04 ,  G02B5/32 ,  G03H1/18

CPC classification number: G03H1/0276 ,  G03F7/00 ,  G03H1/028 ,  G03H1/04 ,  G03H2001/0292 ,  G03H2001/0296 ,  G03H2001/043 ,  G03H2001/0482 ,  G03H2223/14 ,  G03H2224/04 ,  G03H2225/11 ,  G03H2260/14 ,  G03H2260/63 ,  G03H2270/13 ,  G03H2270/21

Abstract: A method and apparatus for producing durable embossing tools is disclosed. An anisotropic etching process, such as ion etching, is used to etch a relief pattern into a hard substrate. A transfer layer is formed overlaying a generally smooth, seamless surface region of a substrate. A desired relief pattern is formed in the transfer layer, by exposing a photoresist, embossing, or the like. The substrate having the photoresist thereon is subjected to an anisotropic etch. The anisotropic etch continues until the transfer layer is completely removed and the relief pattern is formed in the upper surface of the embossing tool. The relative etch rates between the transfer layer and the surface region of the embossing tool are selected to provide the desired depth modulation in the surface of the embossing tool. An embossing tool produced according to the invention has a relatively hard surface and may thus be used for the mass production of holographic images without significant degradation of the pattern. Because the embossing tool can be made from an extremely hard material such as chromium or hardened steel, materials which previously could not be economically embossed with holograms, such as aluminum or steel, may now be embossed by an embossing tool made according to this invention.