公开(公告)号：WO2007106552A3

公开(公告)日：2007-11-29

申请号：PCT/US2007006521

申请日：2007-03-14

Applicant: MICRONICS INC ,  HUNTER WILLIAM SAMUEL

Inventor： HUNTER WILLIAM SAMUEL

IPC: B01L3/00 ,  A61B10/00

CPC classification number: B01F13/0059 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/0096 ,  B01F13/0818 ,  B01L3/502715 ,  B01L3/5029 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/10 ,  B01L2300/0627 ,  B01L2300/1805 ,  B01L2300/1827 ,  B01L2300/185 ,  B01L2400/0683 ,  G01N2001/028

Abstract: A biosafe apparatus is disclosed for assay and diagnosis of respiratory pathogens comprising a nasal sampling device, a single entry, disposable microfluidic cartridge for target nucleic acid amplification, and an instrument with on-board assay control platform and target detection means.

Abstract translation: 公开了用于呼吸道病原体的测定和诊断的生物安全装置，其包括鼻取样装置，用于靶核酸扩增的单入口，一次性微流体盒，以及具有板载测定控制平台和目标检测装置的仪器。

公开(公告)号：WO2008134811A1

公开(公告)日：2008-11-13

申请号：PCT/AU2008000622

申请日：2008-05-02

Applicant: FLUIDYX PTY LTD ,  HUNTER WILLIAM SAMUEL ,  HOPPER WILLIAM ROBB

Inventor： HUNTER WILLIAM SAMUEL ,  HOPPER WILLIAM ROBB

IPC: G01N21/77 ,  A61B5/00

CPC classification number: G01N21/6428 ,  G01N21/645 ,  G01N21/8483 ,  G01N35/00693 ,  G01N2021/6484 ,  G01N2201/0221

Abstract: The invention concerns a portable device for reading a fluorescent-labelled, membrane based assay, to detect the presence of an analyte in a sample. The portable device comprises a light sealed housing which includes a receiving member to receive a membrane based assay. The light sealed housing comprises a first light source for illuminating a first portion of the membrane with light, a first photodetector, a light guide and a microprocessor. The first photodetector is operable to detect fluoresced light emitted by an excited fluorescent label captured by a reagent laid down in the first portion of the membrane and to measure an intensity of the fluoresced light. The light guide guides illuminated light from the first light source to the first portion of the membrane and guides fluoresced light emitted by the excited fluorescent label to the first photodetector. The microprocessor is operable to process the measured intensity of the fluoresced light to determine whether the analyte is present.

Abstract translation: 本发明涉及用于读取荧光标记的基于膜的测定法以检测样品中分析物的存在的便携式设备。 便携式装置包括一个光密封的外壳，它包括一个用于接收基于膜的测定的接收构件。 光密封壳体包括用于用光照亮膜的第一部分的第一光源，第一光电检测器，光导和微处理器。 第一光电检测器可操作以检测由放置在膜的第一部分中的试剂捕获的激发的荧光标记发射的荧光，并测量荧光的强度。 光引导件将来自第一光源的光照射到膜的第一部分，并将由激发的荧光标记发射的荧光的光引导到第一光电检测器。 微处理器可操作地处理所测量的荧光的强度以确定分析物是否存在。

公开(公告)号：WO2008018904A2

公开(公告)日：2008-02-14

申请号：PCT/US2007001170

申请日：2007-01-17

Applicant: ARGOS THERAPEUTICS INC ,  KIRIN BREWERY ,  SPENCE SIMON JONATHON ,  GRANT RICHARD ALEXANDER ,  PEELE TIMOTHY DOYLE ,  HUNTER WILLIAM SAMUEL ,  ABDELMOTELEB ASHRAF F ,  KNEEN DAVID THOMAS ,  NEIL ROBERT ALISTER ,  HARRIS SIMON

Inventor： SPENCE SIMON JONATHON ,  GRANT RICHARD ALEXANDER ,  PEELE TIMOTHY DOYLE ,  HUNTER WILLIAM SAMUEL ,  ABDELMOTELEB ASHRAF F ,  KNEEN DAVID THOMAS ,  NEIL ROBERT ALISTER ,  HARRIS SIMON

IPC: C12M3/00

CPC classification number: G01N35/0099 ,  B01L1/00 ,  B01L1/02 ,  B01L3/021 ,  B01L3/0293 ,  B01L3/5085 ,  B01L7/52 ,  B01L9/06 ,  B01L9/523 ,  B01L2200/02 ,  B01L2200/0642 ,  B01L2200/142 ,  B01L2300/046 ,  B01L2300/06 ,  B01L2300/0838 ,  B01L2300/123 ,  B01L2400/0481 ,  G01L1/00 ,  G01N1/34 ,  G01N35/00732 ,  G01N35/00871 ,  G01N2021/0378 ,  Y10T436/11 ,  Y10T436/2575

Abstract: A system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and/or other sample manipulation device can be attached to the inside of the barrier, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device. The barrier can be flexible, and allow the robotic arm to move the pipette head throughout the work area of the tray. All samples, reagents, pipette tips and other tools or devices for processing nucleic acid samples may remain within the closed compartment provided by the container during processing.

Abstract translation: 用于核酸和其它样品的自动处理的系统和方法包括一个包含托盘和柔性屏障的一次性容器。 阻挡件被构造成与托盘的顶部边缘密封，在密封托盘内提供封闭的无菌工作区域。 移液管头和/或其他样品操纵装置可以附接到屏障的内部，并且屏障可以包括用于机器臂或其它装置的界面。 当屏障被密封在托盘上时，屏障将托盘的内容物与机器人或其他操纵装置分开。 障碍物可以是柔性的，并且允许机器人臂将移液管头移动到托盘的整个工作区域。 用于处理核酸样品的所有样品，试剂，移液器吸头和其他工具或装置可以在处理期间保留在由容器提供的封闭隔室内。