METHODS RELATED TO CTLA4-FC FUSION PROTEINS
    9.
    发明申请
    METHODS RELATED TO CTLA4-FC FUSION PROTEINS 审中-公开
    与CTLA4-FC融合蛋白相关的方法

    公开(公告)号:WO2014149067A1

    公开(公告)日:2014-09-25

    申请号:PCT/US2013/043786

    申请日:2013-05-31

    CPC classification number: C07K14/70521 C07K2319/30

    Abstract: The present disclosure provides, in part, methods for evaluating, identifying, and/or producing (e.g., manufacturing) a CTLA4-Fc fusion protein, e.g., abatacept. In some instances, methods herein allow highly resolved evaluation of abatacept useful for, inter alia, manufacturing abatacept, characterizing abatacept, identifying and/or confirming abatacept, monitoring the structure of abatacept, comparing abatacept preparations made over time or made under different conditions, and/or controlling the structure of abatacept.

    Abstract translation: 本公开部分地提供用于评估,鉴定和/或产生(例如制造)CTLA4-Fc融合蛋白(例如abatacept)的方法。 在某些情况下,这里的方法允许高度分辨的对abatacept的评估,特别是制造abatacept,表征abatacept,鉴定和/或确认abatacept,监测abatacept的结构,比较随时间推移或在不同条件下制备的abatacept制剂, /或控制abatacept的结构。

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