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    MEDICAL MONITORING PATCH DEVICE AND METHODS
    2.
    发明申请
    MEDICAL MONITORING PATCH DEVICE AND METHODS 审中-公开
    医疗监护装置及方法

    公开(公告)号：WO2009124076A1

    公开(公告)日：2009-10-08

    申请号：PCT/US2009/039002

    申请日：2009-03-31

    申请人： NELLCOR PURITAN BENNETT LLC ,  PETERSEN, Ethan ,  PEREZ, Mark

    发明人： PETERSEN, Ethan ,  PEREZ, Mark

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6833 ,  A61B5/14552 ,  A61B2560/0412

    摘要： Embodiments described herein may include systems and methods for monitoring physiological parameters of a patient. Specifically, embodiments disclose the use of a generally self-contained pulse oximeter that is small and lightweight, such that it may be comfortably affixed to a patient to provide physiological data pertaining to the patient. Embodiments also provide methods of using and manufacturing a pulse oximetry patch.

    摘要翻译： 本文描述的实施例可以包括用于监测患者生理参数的系统和方法。 具体地，实施方案公开了使用小而重量轻的通常自包含的脉搏血氧计，使得其可以舒适地附着于患者以提供与患者有关的生理数据。 实施例还提供了使用和制造脉搏血氧饱和度贴片的方法。

    OXIMETER CROSS-TALK REDUCTION
    5.
    发明申请
    OXIMETER CROSS-TALK REDUCTION 审中-公开
    OXIMETER交叉减少

    公开(公告)号：WO2005082241A1

    公开(公告)日：2005-09-09

    申请号：PCT/US2005/006316

    申请日：2005-02-24

    申请人： NELLCOR PURITAN BENNETT INCORPORATED ,  PETERSEN, Ethan ,  CHEW, Bradford, B. ,  SHEA, William

    发明人： PETERSEN, Ethan ,  CHEW, Bradford, B. ,  SHEA, William

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14551 ,  A61B5/7203 ,  A61B5/725

    摘要： A method and apparatus for reducing cross-talk in an oximeter. The oximeter includes a band pass filter. The amount of cross-talk through the band pass filter is estimated. Based on this estimate, the corner frequencies of the band pass filter are adjusted when it is designed to minimize the cross-talk. In one embodiment, a calibration mode is performed when a sensor is attached to the oximeter. In the calibration mode, the signals are measured with first only the red LED on and then with only the IR LED on. Any signal measured in the off channel is assumed to be a result of cross-talk from the other channel. The magnitude of the cross-talk is determined as a percentage, and subsequently the percentage is multiplied by the actual signal and subtracted from the other LED signal as cross-talk compensation.

    摘要翻译： 一种用于减少血氧计中的串扰的方法和装置。 血氧计包括带通滤波器。 估计通过带通滤波器的串扰量。 基于这个估计，当设计带通滤波器的转角频率被设计成使串扰减至最小时。 在一个实施例中，当传感器附接到血氧计时执行校准模式。 在校准模式下，首先测量信号，只有红色LED亮起，然后只有红外LED亮起。 假设在关闭通道中测量的任何信号都是来自另一个通道的串扰结果。 串扰幅度被确定为一个百分比，随后百分比乘以实际信号，并从另一个LED信号中减去作为串扰补偿。

    TECHNIQUES FOR DETECTING HEART PULSES AND REDUCING POWER CONSUMPTION IN SENSORS
    6.
    发明申请
    TECHNIQUES FOR DETECTING HEART PULSES AND REDUCING POWER CONSUMPTION IN SENSORS 审中-公开
    用于检测心脏脉搏并降低传感器功耗的技术

    公开(公告)号：WO2005082240A1

    公开(公告)日：2005-09-09

    申请号：PCT/US2005/006208

    申请日：2005-02-25

    申请人： NELLCOR PURITAN BENNETT INCORPORATED ,  NORDSTROM, Brad ,  SHEA, William ,  PETERSEN, Ethan

    发明人： NORDSTROM, Brad ,  SHEA, William ,  PETERSEN, Ethan

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14551 ,  A61B5/02416 ,  A61B5/7207 ,  A61B5/7239 ,  A61B2560/0209

    摘要： Low power techniques for sensing cardiac pulses in a signal from a sensor (101) are provided. A pulse detection block (102) senses the sensor signal and determines its signal-to-noise ratio. After comparing the signal-to-noise ratio to a threshold, the drive current of light emitting elements in the sensor is dynamically adjusted to reduce power consumption while maintaining the signal-to-noise ratio at an adequate level. The signal component of the sensor signal can be measured by identifying systolic transitions. The systolic transitions are detected using a maximum and minimum derivative averaging scheme. The moving minimum (301) and the moving maximum (304) are compared to the scaled sum (312, 313) of the moving minimum and moving maximum to identify the systolic transitions. Once the signal component has been identified, the signal component is compared to a noise component to calculate the signal-to-noise ratio.

    摘要翻译： 提供了用于感测来自传感器（101）的信号中的心脏脉冲的低功率技术。 脉冲检测块（102）感测传感器信号并确定其信噪比。 在将信噪比与阈值进行比较之后，动态地调节传感器中的发光元件的驱动电流以降低功耗，同时将信噪比保持在适当的水平。 可以通过识别收缩转变来测量传感器信号的信号分量。 使用最大和最小导数平均方案检测心脏收缩转变。 将移动最小值（301）和移动最大值（304）与移动最小值和移动最大值的缩放和（312,313）进行比较，以识别收缩转换。 一旦识别出信号分量，就将信号分量与噪声分量进行比较，以计算信噪比。

    DELTA-SIGMA MODULATOR FOR OUTPUTTING ANALOG REPRESENTATION OF PHYSIOLOGICAL SIGNAL
    7.
    发明申请
    DELTA-SIGMA MODULATOR FOR OUTPUTTING ANALOG REPRESENTATION OF PHYSIOLOGICAL SIGNAL 审中-公开
    用于输出生理信号的模拟表示的DELTA-SIGMA调制器

    公开(公告)号：WO2005082237A1

    公开(公告)日：2005-09-09

    申请号：PCT/US2005/005934

    申请日：2005-02-24

    申请人： NELLCOR PURITAN BENNETT INCORPORATED ,  PETERSEN, Ethan ,  SHEA, William ,  CHEW, Bradford, B.

    发明人： PETERSEN, Ethan ,  SHEA, William ,  CHEW, Bradford, B.

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14551 ,  H03M7/3028 ,  H03M7/3042

    摘要： A method and apparatus for providing a substantially real-time representation of an analog representation of a physiological signal. The waveform signal from the sensor is converted into digital form. A delta-sigma modulator is used as a simple Digital-to-analog Converter (ADC). The output can then be provided through a simple hardware filter to give an analog output signal in nearly real-time, which can be used for other instruments, synchronization, display, etc.

    摘要翻译： 一种用于提供生理信号的模拟表示的基本上实时表示的方法和装置。 传感器的波形信号转换为数字形式。 Δ-Σ调制器用作简单的数模转换器（ADC）。 然后可以通过简单的硬件滤波器提供输出，几乎实时提供模拟输出信号，可用于其他仪器，同步，显示等。

    PARTICLE SENSOR WITH WIDE LINEAR RANGE
    8.
    发明申请
    PARTICLE SENSOR WITH WIDE LINEAR RANGE 审中-公开

    公开(公告)号：WO2009017721A3

    公开(公告)日：2009-02-05

    申请号：PCT/US2008/009144

    申请日：2008-07-28

    申请人： BUGLAB LLC ,  DEBRECZENY, Martin, P. ,  ROMERO, Jaime ,  PETERSEN, Ethan

    发明人： DEBRECZENY, Martin, P. ,  ROMERO, Jaime ,  PETERSEN, Ethan

    IPC分类号： G01N15/02 ,  G01N21/49

    摘要： This invention provides a novel methods and devices for measurement of particle concentration or changes in particle concentration over a wide linear range. The invention comprises one or more radiation sources and one or more detectors contained in a housing which is interfaced to a medium containing particulate matter. The one or more radiation sources are directed into the medium, scattered or transmitted by the particulate matter, and then some portion of the radiation is detected by the one or more detectors. Methods for confining the measurement to a specific volume within the medium are described. Algorithms are provided for combining the signals generated by multiple source-detector pairs in a manner that results in a wide linear range of response to changes in particle concentration. In one embodiment the sensor provides non¬ invasive measurements of biomass in a bioreactor. In another embodiment an immersible probe design is described, which may be suited for one-time use. In an addition embodiment, a sensor is provided which is well suited to the rapid sequential measurement of particle concentration in multiple vessels, such as assessment of biomass in series of shake flasks.

    OXIMETER AMBIENT LIGHT CANCELLATION
    9.
    发明申请
    OXIMETER AMBIENT LIGHT CANCELLATION 审中-公开
    OXIMETER环保灯消除

    公开(公告)号：WO2005082242A1

    公开(公告)日：2005-09-09

    申请号：PCT/US2005/006336

    申请日：2005-02-24

    申请人： NELLCOR PURITAN BENNETT INCORPORATED ,  PETERSEN, Ethan ,  SHEA, William ,  CHEW, Bradford, B.

    发明人： PETERSEN, Ethan ,  SHEA, William ,  CHEW, Bradford, B.

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14552 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7225 ,  A61B5/7228 ,  A61B5/725 ,  A61B5/7278

    摘要： A pulse oximeter method and apparatus which provides (1) a notch filter (46) at a distance between a modulation frequency and a common multiple of commonly used power line frequencies (50, 60, 100 and 120) and also (2) a demodulation frequency greater than a highest pulse rate of a person and lower than any harmonic of 50, 60, 100 or 120 Hz, to filter ambient light interference, while choosing an optimum demodulation frequency that avoids interference from the notch filter or from harmonics of the line interference. Also, ambient light for any low frequency interference, such as power line interference, is measured both before and after each of the light emitter wavelengths and the average of the ambient light is then subtracted from the detected signal.

    摘要翻译： 一种脉冲血氧计方法和装置，其提供（1）在调制频率和常用电力线频率（50,60,100和120）的公倍数之间的距离处的陷波滤波器（46），以及（2）解调 频率大于人的最高脉冲频率，并且低于50,60,100或120Hz的任何谐波，以滤除环境光干扰，同时选择避免来自陷波滤波器或线路谐波的干扰的最佳解调频率 干扰。 此外，在每个发光体波长之前和之后都测量任何低频干扰（例如电力线干扰）的环境光，然后从检测到的信号中减去环境光的平均值。

    OXIMETER RED AND IR ZERO CALIBRATION CONTROL
    10.
    发明申请
    OXIMETER RED AND IR ZERO CALIBRATION CONTROL 审中-公开
    OXIMETER红色和红外零点校准控制

    公开(公告)号：WO2005082238A1

    公开(公告)日：2005-09-09

    申请号：PCT/US2005/006206

    申请日：2005-02-25

    申请人： NELLCOR PURITAN BENNETT INCORPORATED ,  CHEW, Bradford, B. ,  PETERSEN, Ethan ,  SHEA, William

    发明人： CHEW, Bradford, B. ,  PETERSEN, Ethan ,  SHEA, William

    IPC分类号： A61B5/00

    CPC分类号： A61B5/1495 ,  A61B5/14551

    摘要： A pulse oximeter with drive lines for driving red and IR LEDs, and a drive circuit for driving those drive lines. A processor controls the drive circuit using a red zero output line and an IR zero output line directly connected between the processor and the drive circuit. This allows a control signal to directly control the turning off of either the red or IR drive transistors to prevent forward current flow through the red and IR LEDs by overriding the ongoing programmable logic state machine control of the drive transistors. The effects of crosstalk and capacitive coupling are reduced as a result.

    摘要翻译： 具有用于驱动红色和红外LED的驱动线的脉冲血氧计，以及用于驱动这些驱动线的驱动电路。 处理器使用红色零输出线和直接连接在处理器和驱动电路之间的IR零输出线来控制驱动电路。 这允许控制信号直接控制红色或红外驱动晶体管的关断，以通过覆盖驱动晶体管的正在进行的可编程逻辑状态机控制来防止正向电流流过红色和红外LED。 结果，减少串扰和电容耦合的影响。