公开(公告)号：WO2015095553A1

公开(公告)日：2015-06-25

申请号：PCT/US2014/071212

申请日：2014-12-18

Applicant: NEPHROGENESIS, LLC

Inventor： TUMLIN, James

IPC: A61K38/17 ,  A61P39/06

CPC classification number: A61M1/1676 ,  A61M1/16 ,  A61M1/3496 ,  A61M1/3643 ,  A61M1/3644 ,  A61M1/3649 ,  A61M1/3679 ,  B01D61/243 ,  B01D71/16 ,  B01D71/42 ,  B01D71/56 ,  B01D71/68 ,  B01D2311/2626 ,  B01D2311/2688 ,  B01J2220/4856

Abstract: The present disclosure relates to a dialysis apparatus comprising a membrane having at least one protein from the lipocalin family bound thereon. The disclosure further relates to methods of removing non-polar, hydrophobic and/or protein bound uremic toxins from a target subject utilizing the dialysis apparatus described herein.

Abstract translation: 本公开涉及一种透析装置，其包括具有结合于其上的脂笼蛋白家族的至少一种蛋白质的膜。 本公开还涉及使用本文所述的透析装置从目标受试者去除非极性，疏水和/或蛋白结合的尿毒症毒素的方法。