公开(公告)号：WO2017054109A1

公开(公告)日：2017-04-06

申请号：PCT/CN2015/090942

申请日：2015-09-28

Applicant: NESTEC S.A.

Inventor： THAKKAR, Sagar ,  AFFOLTER, Michael ,  DE CASTRO, Carlos Antonio

IPC: A23L1/29 ,  A23C9/00

CPC classification number: A23L33/40 ,  A23L33/175

Abstract: Gender specific synthetic nutritional compositions comprising phenylalanine in concentrations reflecting those found in human milk produced by mothers of infants of the corresponding gender at the corresponding stage of lactation, and nutritional systems comprising them.

Abstract translation: 包含苯丙氨酸的性别特异性合成营养组合物，其浓度反映了哺乳期相应阶段的相应性别的母亲产生的人乳中发现的浓度，以及包含它们的营养系统。

公开(公告)号：WO2019106060A1

公开(公告)日：2019-06-06

申请号：PCT/EP2018/082923

申请日：2018-11-29

Applicant: NESTEC S.A.

Inventor： GARCIA-RODENAS, Clara,Lucia ,  AFFOLTER, Michael

IPC: A61K31/07 ,  A61K31/355 ,  A61K31/455 ,  A61K33/30 ,  A23L33/00 ,  A23L33/15 ,  A23L33/155 ,  A61K33/04 ,  A61P43/00

Abstract: A maternal composition wherein said maternal composition is specifically formulated for a woman who has given birth prematurely or who is at risk of giving birth prematurely

公开(公告)号：WO2012042013A1

公开(公告)日：2012-04-05

申请号：PCT/EP2011/067096

申请日：2011-09-30

Applicant: NESTEC S.A. ,  AFFOLTER, Michael ,  BUREAU-FRANZ, Isabelle ,  MAYNARD, Françoise ,  MERCENIER, Annick ,  PANCHAUD, Alexandre

Inventor： AFFOLTER, Michael ,  BUREAU-FRANZ, Isabelle ,  MAYNARD, Françoise ,  MERCENIER, Annick ,  PANCHAUD, Alexandre

IPC: A61K38/01 ,  A23J3/34 ,  A23L1/305 ,  A61P37/08

CPC classification number: A61K39/35 ,  A23C9/1526 ,  A23J3/343 ,  A23J3/344 ,  A23L33/18 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K38/018 ,  C12N9/52 ,  A23V2200/304 ,  A23V2250/55

Abstract: A composition comprising protein hydrolysates derived from milk is obtained by the treatment of enzymes derived from microorganisms. A trypsin-like enzyme and a chemotrypsin-like enzyme are used. The composition is in particular intended for inducing tolerance in infants with the effect of modulating the potential occurrence of allergies later in life. The composition can also be used in sick adult patients. Preferably the composition is an infant formula, infant follow-up formula, growing-up milk or baby food or an enteral complete nutritional composition.

Abstract translation: 通过处理来源于微生物的酶获得包含来自牛奶的蛋白质水解产物的组合物。 使用胰蛋白酶样酶和抗肌钙蛋白酶。 该组合物特别用于诱导婴儿的耐受性，其具有调节生命后期可能发生的过敏的作用。 该组合物也可用于病态成人患者。 优选地，组合物是婴儿配方食品，婴儿后续配方，成长中的牛奶或婴儿食品或肠内完全营养组合物。

公开(公告)号：WO2009149880A1

公开(公告)日：2009-12-17

申请号：PCT/EP2009/004092

申请日：2009-06-08

Applicant: NESTEC S.A. ,  GRIGOROV, Martin ,  GERMOND, Jacques-Edouard ,  TOURNADE, Sylvie ,  AFFOLTER, Michael

Inventor： GRIGOROV, Martin ,  GERMOND, Jacques-Edouard ,  TOURNADE, Sylvie ,  AFFOLTER, Michael

IPC: A23C9/123 ,  A23C9/13 ,  A23L1/305 ,  C07K5/08 ,  A61P9/12

CPC classification number: A23C9/1234 ,  A23C9/1322 ,  A23L33/18 ,  A23Y2220/39 ,  C07K5/0808

Abstract: The present invention relates to novel strains of Lactobacillus helveticus that can produce high amounts of hypotensive peptides, in particular IPP, VPP and LPP. It also relates to a fermented milk product containing a mixture of tripeptides IPP-VPP-LPP and a strain of L. helveticus. The invention further relates to the specific peptide mixture consisting of tripeptides IPP, VPP and LPP and the use of the fermented product or mixture of peptides in food products, food supplement or pharmaceutical compositions for reducing or preventing hypertension.

Abstract translation: 本发明涉及可产生大量降血压肽，特别是IPP，VPP和LPP的新型瑞士乳杆菌菌株。 它还涉及含有三肽IPP-VPP-LPP和瑞士乳杆菌菌株的混合物的发酵乳制品。 本发明还涉及由三肽IPP，VPP和LPP组成的特定肽混合物，以及食品中的发酵产物或肽混合物的用途，用于降低或预防高血压的食品补充剂或药物组合物。

公开(公告)号：WO2017054107A1

公开(公告)日：2017-04-06

申请号：PCT/CN2015/090939

申请日：2015-09-28

Applicant: NESTEC S.A.

Inventor： THAKKAR, Sagar ,  AFFOLTER, Michael ,  DE CASTRO, Carlos Antonio

IPC: A23L1/29 ,  A23C9/00

CPC classification number: A23L33/175 ,  A23L33/40

Abstract: Gender specific synthetic nutritional compositions comprising glycine in concentrations reflecting those found in human milk produced by mothers of infants of the corresponding gender at the corresponding stage of lactation, and nutritional systems comprising them.

Abstract translation: 性别特异性的合成营养组合物，其包含浓度反映在哺乳期相应阶段由对应性别的婴儿母亲产生的人乳中浓度的甘氨酸，以及包含它们的营养系统。

公开(公告)号：WO2006037655A3

公开(公告)日：2006-04-13

申请号：PCT/EP2005/010837

申请日：2005-10-07

Applicant: NESTEC S.A. ,  GRIGOROV, Martin ,  VAN BLADEREN, Peter ,  ZACHARIAE, Ulrich ,  KOCHHAR, Sunil ,  FAY, Laurent-Bernard ,  CORTHESY-THEULAZ, Irène ,  JUILLERAT, Marcel-Alexandre ,  AFFOLTER, Michael

Inventor： GRIGOROV, Martin ,  VAN BLADEREN, Peter ,  ZACHARIAE, Ulrich ,  KOCHHAR, Sunil ,  FAY, Laurent-Bernard ,  CORTHESY-THEULAZ, Irène ,  JUILLERAT, Marcel-Alexandre ,  AFFOLTER, Michael

IPC: C12P21/06 ,  A23J3/34 ,  C07K14/575 ,  C07K14/72

Abstract: The present invention is directed to procedures for the controlled natural bioprocessing of naturally occurring biological molecules by processing activities present in select organisms, extracts of such organisms or other natural processing agents. The invention also covers the methods for developing these procedures and compositions prepared by the procedures.

公开(公告)号：WO2019106147A1

公开(公告)日：2019-06-06

申请号：PCT/EP2018/083141

申请日：2018-11-30

Applicant: NESTEC S.A.

Inventor： AFFOLTER, Michael ,  AMEYE, Laurent ,  GARCIA-RODENAS, Clara,Lucia

IPC: A61K31/07 ,  A61K31/355 ,  A61K31/455 ,  A61K31/7016 ,  A61K31/702 ,  A61K33/04 ,  A61K33/30 ,  A61K33/34 ,  A23L33/00 ,  A23L33/19 ,  A61P43/00 ,  A23L33/10 ,  A23L33/16 ,  A23L33/125

Abstract: The present invention relates to a preterm human milk fortifier composition, more specifically to a preterm milk fortifier composition providing one or more specific nutrient in amounts that are missing in human milk of women who gave birth to a preterm infant. In particular the present invention relates to a fortifier composition designed for infants as a supplement to preterm human breast milk at the time the infant leaves the hospital (discharge) and after. The invention furthermore relates to the use of said preterm human milk fortifier composition.