公开(公告)号：WO2017134307A1

公开(公告)日：2017-08-10

申请号：PCT/EP2017/052554

申请日：2017-02-06

Applicant: NNE PHARMAPLAN A/S

Inventor： KNUDSEN, Hans Stenberg ,  MELANDER, Matias ,  HALKJÆR PEDERSEN, Jakob

IPC: A61J1/20 ,  A61M39/10

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61M2039/1044 ,  A61M2039/1077 ,  A61M2207/00

Abstract: The present invention relates to a pharmaceutical adaptor system. The pharmaceutical adaptor system comprises a syringe assembly having an axial extension and comprising a first end part and a second end part, the first end part having a male tubular projection, the syringe assembly comprising a syringe and a connecting element having a first mechanical connection part, a unit such as a needle, a vial, a catheter or an IV line, and an adaptor providing fluid communication between the syringe and the unit and having a second mechanical connection part configured to engage with the first mechanical connection part in an engagement direction, thereby in fully engaged position preventing further relative axial movement between the adaptor and the male tubular projection, wherein the adaptor comprises a sealing element configured to receive the male tubular projection and provide sealing between the male tubular projection and the adaptor. The present invention also relates to a pharmaceutical kit system comprising a pharmaceutical adaptor system according to the present invention.

Abstract translation: 药物适配器系统技术领域本发明涉及一种药物适配器系统。 所述药物适配器系统包括具有轴向延伸部并且包括第一端部和第二端部的注射器组件，所述第一端部具有阳性管状突出部，所述注射器组件包括注射器和连接元件，所述连接元件具有第一机械连接部分 ，诸如针，小瓶，导管或IV线的单元以及提供注射器与单元之间的流体连通的适配器，并且具有第二机械连接部分，该第二机械连接部分被配置为在接合方向上与第一机械连接部分接合 ，从而处于完全接合位置，防止适配器与阳性管状凸起之间的进一步的相对轴向运动，其中适配器包括密封元件，该密封元件构造成接收阳性管状凸起并提供阳性管状凸起与适配器之间的密封。 本发明还涉及包含根据本发明的药物接头系统的药物套件系统。

公开(公告)号：WO2017072333A1

公开(公告)日：2017-05-04

申请号：PCT/EP2016/076156

申请日：2016-10-28

Applicant: NNE PHARMAPLAN A/S

Inventor： KNUDSEN, Hans Stenberg ,  PLAMBECH, Christian ,  ØHLENSCHLÆGER, Rasmus ,  JØRGENSEN, Jørgen

IPC: A61M5/145 ,  A61M5/20 ,  A61M5/32 ,  A61M5/315 ,  A61M5/142

CPC classification number: A61M5/1454 ,  A61M5/2033 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/14256 ,  A61M2005/14506 ,  A61M2005/206 ,  A61M2005/31518 ,  A61M2005/3267

Abstract: The present invention relates to a single-use auto-injector for injection of a dosage of a drug into a human body, comprising a housing, and a dosing unit arranged in at least part of the housing, the dosing unit comprising, a needle, a drug container comprising the drug, a piston movable in the container, a first mechanical power supply for supplying a first mechanical force for moving the piston to deliver a drug to the human body, an activation mechanism configured to release the first mechanical power of the first mechanical power supply, and a mechanical escapement mechanism for controlling the movement of the piston, wherein the auto-injector comprises a second mechanical power supply for supplying a second mechanical force, the auto-injector having, a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate the human body for dosing the drug, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks, wherein the second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state by releasing the second mechanical power.

Abstract translation: 本发明涉及一种用于将剂量的药物注射到人体内的单次使用的自动注射器，其包括壳体和设置在壳体的至少一部分中的给药单元， 所述给药单元包括针头，包括所述药物的药物容器，在所述容器中可移动的活塞，用于供应第一机械力的第一机械动力源，所述第一机械动力供应用于移动所述活塞以将药物递送至人体，配置的致动机构 以释放所述第一机械动力源的第一机械动力，以及用于控制所述活塞的运动的机械擒纵机构，其中所述自动注射器包括用于供应第二机械力的第二机械动力源， 第一状态和第二状态，在第一状态中针保护免受针损伤或污染，第二状态中针准备好穿透人体用于给药;第三状态，针具有双侧 训练人体并且准备好剂量;以及第四状态，在所述第四状态中针被屏蔽以避免意外针刺，其中第二机械电源被配置为将自动注射器的状态从第三状态转变到第四状态 通过释放第二个机械动力。