公开(公告)号：WO2017001701A1

公开(公告)日：2017-01-05

申请号：PCT/EP2016/065682

申请日：2016-07-04

Applicant: NOVOZYMES A/S ,  DSM IP ASSETS B.V.

Inventor： SANDVANG, Dorthe, Hoej ,  GAD, Esben ,  KELLY, Nicholas, Michael ,  KLAUSEN, Mikkel ,  THOEGERSEN, Juliane, Charlotte, Gregaard ,  OLSEN, Peter, Bjarke ,  NIELSEN, Preben ,  COHN, Marianne, Thorup

IPC: A23K10/10 ,  A23K20/147

CPC classification number: A23K20/189 ,  A61K9/0053 ,  A61K38/465 ,  A61K38/47 ,  C12Y301/03026 ,  C12Y302/01017 ,  A61K2300/00

Abstract: The present invention relates to animal feed compositions comprising polypeptides having lysozyme activity and polypeptides having phytase activity and uses thereof.

Abstract translation: 本发明涉及包含具有溶菌酶活性的多肽和具有植酸酶活性的多肽的动物饲料组合物及其应用。

公开(公告)号：WO2018113743A1

公开(公告)日：2018-06-28

申请号：PCT/CN2017/117753

申请日：2017-12-21

Applicant: NOVOZYMES A/S ,  LIU, Ye

Inventor： LIU, Ye ,  KLAUSEN, Mikkel ,  SCHNORR, Kirk Matthew ,  SKOV, Lars Kobberoee ,  NYMAND-GRARUP, Soeren ,  COHN, Marianne, Thorup ,  OLSEN, Peter, Bjarke ,  LI, Ming

IPC: C12N9/36 ,  A61K38/47

Abstract: Animal feed or animal feed additives comprising one or more polypeptides having lysozyme activity are disclosed. Polypeptides having lysozyme activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides are also provided.

公开(公告)号：WO2018113745A1

公开(公告)日：2018-06-28

申请号：PCT/CN2017/117765

申请日：2017-12-21

Applicant: NOVOZYMES A/S ,  LI, Ming

Inventor： LI, Ming ,  KLAUSEN, Mikkel ,  SCHNORR, Kirk Matthew ,  NYMAND-GRARUP, Soren ,  OLSEN, Peter Bjarke ,  COHN, Marianne Thorup ,  OLINSKI, Robert Piotr ,  MORANT, Marc Dominique ,  LIU, Ye ,  SKOV, Lars Kobberoee ,  SKOVLUND, Dominique Aubert ,  HAN, Bucong

IPC: A61K38/47 ,  C12N9/24 ,  C12N9/36 ,  C12N15/56 ,  C11D3/386

Abstract: Provided are animal feed or animal feed additives comprising one or more polypeptides having lysozyme activity. Provived are polypeptides having lysozyme activity, polynucleotides encoding the polypeptides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

公开(公告)号：WO2020193407A1

公开(公告)日：2020-10-01

申请号：PCT/EP2020/057780

申请日：2020-03-20

Applicant: NOVOZYMES A/S

Inventor： KLAUSEN, Mikkel ,  FREDERIKSEN, Carsten, Oestergaard

IPC: C12N9/24

Abstract: Muramic acid measurements in acid hydrolysed digesta samples are used to measure the activity of peptidoglycan hydrolyzing enzyme, as illustrated by the use of a muramidase, as determined by the degree of peptidoglycan hydrolysis, in the gastrointestinal tract of animals fed supplements with the muramidase.

公开(公告)号：WO2013076253A1

公开(公告)日：2013-05-30

申请号：PCT/EP2012/073483

申请日：2012-11-23

Applicant: NOVOZYMES A/S

Inventor： SCHNORR, Kirk, Matthew ,  NIELSEN, Jens, Erik ,  KLAUSEN, Mikkel

IPC: A61K38/47 ,  C12N9/24 ,  C12N9/36 ,  C12N15/56 ,  C11D3/386

CPC classification number: C12N9/2462 ,  A23K20/174 ,  A23K20/184 ,  A23K20/189 ,  A23K20/20 ,  A23K40/20 ,  A23K40/25 ,  A23K50/75 ,  A23K50/80 ,  A61K38/00 ,  C11B1/102 ,  C11D3/38636 ,  C12N15/1003 ,  C12Y302/01017

Abstract: The present invention relates to isolated polypeptides having lysozymeactivity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

Abstract translation: 本发明涉及具有溶菌酶活性的分离多肽和编码多肽的多核苷酸。 本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及产生和使用多肽的方法。

公开(公告)号：WO2014180953A1

公开(公告)日：2014-11-13

申请号：PCT/EP2014/059449

申请日：2014-05-08

Applicant: NOVOZYMES A/S

Inventor： KLAUSEN, Mikkel ,  LASSEN, Klaus Skaalum

IPC: A23K1/165 ,  A23K1/18 ,  A61K38/44 ,  A61P1/12

CPC classification number: A61K38/443 ,  A23K10/14 ,  A23K10/30 ,  A23K20/142 ,  A23K20/174 ,  A23K20/189 ,  A23K20/195 ,  A23K20/20 ,  A23K40/20 ,  A23K40/25 ,  A23K50/75 ,  A23V2002/00 ,  A61K38/44 ,  A61K45/06 ,  A23V2200/3204

Abstract: The present invention relates to methods of controlling the growth of microorganisms in animals and animal feed. In particular, the present invention relates to a method of controlling the growth of microorganisms in animals with an antimicrobial composition, the treatment of animal feed with an antimicrobial additive and antimicrobial compositions.

Abstract translation: 本发明涉及控制动物和动物饲料中微生物生长的方法。 特别地，本发明涉及用抗微生物组合物控制动物微生物生长的方法，用抗微生物添加剂和抗微生物组合物处理动物饲料。

公开(公告)号：WO2012035103A1

公开(公告)日：2012-03-22

申请号：PCT/EP2011/066015

申请日：2011-09-15

Applicant: NOVOZYMES A/S ,  KLAUSEN, Mikkel ,  ALLESEN-HOLM, Marie ,  DE MARIA, Leonardo ,  SKJOET, Michael

Inventor： KLAUSEN, Mikkel ,  ALLESEN-HOLM, Marie ,  DE MARIA, Leonardo ,  SKJOET, Michael

IPC: C07K14/465 ,  C12N9/36

CPC classification number: C12N9/2462 ,  A23K20/189 ,  A61K38/47 ,  C11D3/38636 ,  C12Y302/01017

Abstract: The present invention is directed to lysozyme variants and nucleotide sequences encoding same. The lysozyme variants have antimicrobial and/or lysozyme activity and comprise an alteration of an amino acid sequence at one or more positions. The present invention is also directed to methods for producing and of using the Opisthocomus hoazin lysozyme and the lysozyme variants of the present invention as antimicrobial agents.

Abstract translation: 本发明涉及溶菌酶变体和编码其的核苷酸序列。 溶菌酶变体具有抗微生物和/或溶菌酶活性，并且包括在一个或多个位置上氨基酸序列的改变。 本发明还涉及用于制造和使用本发明的眼药水溶菌酶和溶菌酶变体作为抗微生物剂的方法。