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公开(公告)号：WO2019191229A8
公开(公告)日：2019-10-03
申请号：PCT/US2019/024278
申请日：2019-03-27
发明人： SYDORENKO, Nadiya , ALAM, Md, Rauful , AMEDZO, Lukiana , BABU, Suresh , BAIAZITOV, Ramil, Y. , BARRAZA, Scott, J. , BHATTACHARYYA, Anuradha , KARP, Gary, Mitchell , KENTON, Nathaniel, T. , MAZZOTTI, Anthony, R. , MOON, Young-Choon , MSZAR, Nicholas, W. , NARASIMHAN, Jana , PAL, Sudipta , PATEL, Jigar, S. , TURPOFF, Anthony , WOLL, Mathew, G. , XU, Zhenrong , ZHANG, Nanjing
IPC分类号： A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
摘要： The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：WO2019191229A1
公开(公告)日：2019-10-03
申请号：PCT/US2019/024278
申请日：2019-03-27
发明人： SYDORENKO, Nadiya , ALAN, Md, Rauful , AMEDZO, Lukiana , BABU, Suresh , BAIAZITOV, Ramil, Y. , BARRAZA, Scott, J. , BHATTACHARYYA, Anuradha , KARP, Gary, Mitchell , KENTON, Nathaniel, T. , MAZZOTTI, Anthony, R. , MOON, Young-Choon , MSZAR, Nicholas, W. , NARASIMHAN, Jana , PAL, Sudipta , PATEL, Jigar, S. , TURPOFF, Anthony , WOLL, Mathew, G. , XU, Zhenrong , ZHANG, Nanjing
IPC分类号： A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
摘要： The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I) or Formula (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：WO2021207453A1
公开(公告)日：2021-10-14
申请号：PCT/US2021/026316
申请日：2021-04-08
发明人： SYDORENKO, Nadiya , ALAM, Md, Rauful , BABU, Suresh , BHATTACHARYYA, Anuradha , CHEN, Guangming , CHIERCHIA, Matteo , KARP, Gary, Mitchell , LUONG, Tom, Tuan , MAZZOTTI, Anthony, R. , MOON, Young-Choon , MSZAR, Nicholas, Walter , NARASIMHAN, Jana , PATEL, Jigar, S. , REN, Hongyu , WANG, Gang , WOLL, Matthew, G. , ZHANG, Nanjing , ZHANG, Xiaoyan
IPC分类号： C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D498/04 , C07D513/04 , A61K31/53 , A61P25/28
摘要： The present description relates to compounds of Formula (I), forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：WO2019191092A8
公开(公告)日：2019-10-03
申请号：PCT/US2019/024068
申请日：2019-03-26
发明人： SYDORENKO, Nadiya , BABU, Suresh , BHATTACHARYYA, Anuradha , MOON, Young-Choon , NARASIMHAN, Jana , PATEL, Jigar, S.
IPC分类号： C07D241/12 , C07D241/20 , C07D401/14
摘要： The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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公开(公告)号：WO2019191092A1
公开(公告)日：2019-10-03
申请号：PCT/US2019/024068
申请日：2019-03-26
发明人： SYDORENKO, Nadiya , BABU, Suresh , BHATTACHARYYA, Anuradha , MOON, Young-choon , NARASIMHAN, Jana , PATEL, Jigar, S.
IPC分类号： C07D241/12 , C07D241/20 , C07D401/14
摘要： The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
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