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    DETECTION SCHEME FOR X-RAY SMALL ANGLE SCATTERING
    2.
    发明申请
    DETECTION SCHEME FOR X-RAY SMALL ANGLE SCATTERING 审中-公开

    公开(公告)号：WO2019126458A1

    公开(公告)日：2019-06-27

    申请号：PCT/US2018/066736

    申请日：2018-12-20

    Applicant: RENSSELAER POLYTECHNIC INSTITUTE

    Inventor： WANG, Ge ,  LI, Guang ,  CONG, Wenxiang

    IPC: A61B6/00

    Abstract: A detection scheme for x-ray small angle scattering is described. An x-ray small angle scattering apparatus may include a first grating and a complementary second grating. The first grating includes a plurality of first grating cells. The complementarity second grating includes a plurality of second grating cells. The second grating is positioned relative to the first grating. A configuration of the first grating, a configuration of the second grating and the relative positioning of the gratings are configured to pass one or more small angle scattered photons and to block one or more Compton scattered photons and one or more main x-ray photons.

    TOMOGRAPHIC IMAGE RECONSTRUCTION VIA MACHINE LEARNING
    3.
    发明申请
    TOMOGRAPHIC IMAGE RECONSTRUCTION VIA MACHINE LEARNING 审中-公开
    机器学习的人体图像重建

    公开(公告)号：WO2017223560A1

    公开(公告)日：2017-12-28

    申请号：PCT/US2017/039274

    申请日：2017-06-26

    Applicant: RENSSELAER POLYTECHNIC INSTITUTE

    Inventor： WANG, Ge ,  CONG, Wenxiang ,  YANG, Qingsong

    IPC: G06N3/08 ,  G06N3/04 ,  G06N99/00 ,  A61B6/03 ,  A61B5/055 ,  A61B5/00

    Abstract: Tomographic/tomosynthetic image reconstruction systems and methods in the framework of machine learning, such as deep learning, are provided. A machine learning algorithm can be used to obtain an improved tomographic image from raw data, processed data, or a preliminarily reconstructed intermediate image for biomedical imaging or any other imaging purpose. In certain cases, a single, conventional, non-deep-learning algorithm can be used on raw imaging data to obtain an initial image, and then a deep learning algorithm can be used on the initial image to obtain a final reconstructed image. All machine learning methods and systems for tomographic image reconstruction are covered, except for use of a single shallow network (three layers or less) for image reconstruction.

    Abstract translation: 提供了机器学习框架中的层析/断层合成图像重建系统和方法，例如深度学习。 机器学习算法可用于从原始数据，处理的数据或用于生物医学成像或任何其他成像目的的初步重建的中间图像获得改进的层析图像。 在某些情况下，可以在原始成像数据上使用单一的常规非深度学习算法来获得初始图像，然后可以在初始图像上使用深度学习算法以获得最终重建图像。 除了使用单个浅层网络（三层或更少）进行图像重建外，所有用于断层扫描图像重建的机器学习方法和系统都已涵盖。

    IMAGE RECONSTRUCTION METHOD FOR COMPUTED TOMOGRAPHY
    4.
    发明申请
    IMAGE RECONSTRUCTION METHOD FOR COMPUTED TOMOGRAPHY 审中-公开

    公开(公告)号：WO2017205379A3

    公开(公告)日：2017-11-30

    申请号：PCT/US2017/034011

    申请日：2017-05-23

    Applicant: RENSSELAER POLYTECHNIC INSTITUTE

    Inventor： WANG, Ge ,  CONG, Wenxiang ,  YANG, Qingsong

    IPC: A61B6/00 ,  A61B6/03 ,  G06T5/00

    Abstract: Systems and methods for reconstructing images for computed tomography are provided. Image reconstruction can be based on a realistic polychromatic physical model, and can include use of both an analytical algorithm and a single-variable optimization method. The optimization method can be used to solve the non-linear polychromatic X- ray integral model in the projection domain, resulting in an accurate decomposition for sinograms of two physical basis components.

    STATIONARY IN-VIVO GRATING-ENABLED MICRO-CT ARCHITECTURE (SIGMA)
    6.
    发明申请
    STATIONARY IN-VIVO GRATING-ENABLED MICRO-CT ARCHITECTURE (SIGMA) 审中-公开

    公开(公告)号：WO2019090299A1

    公开(公告)日：2019-05-09

    申请号：PCT/US2018/059366

    申请日：2018-11-06

    Applicant: RENSSELAER POLYTECHNIC INSTITUTE

    Inventor： WANG, Ge ,  CONG, Wenxiang ,  YANG, Qingsong ,  LI, Guang

    IPC: A61B6/03 ,  G01N23/04 ,  G21K1/00 ,  H01J5/16

    Abstract: A stationary in-vivo grating-enabled micro-CT (computed tomography) architecture (SIGMA) system includes CT scanner control circuitry and a number of imaging chains. Each imaging chain includes an x-ray source array, a phase grating, an analyzer grating and a detector array. Each imaging chain is stationary and each x-ray source array includes a plurality of x-ray source elements. Each imaging chain has a centerline, the centerlines of the number of imaging chains intersect at a center point and a first angle between the centerlines of a first adjacent pair of imaging chains equals a second angle between the centerlines of a second adjacent pair of imaging chains. A plurality of selected x-ray source elements of a first x-ray source array is configured to emit a plurality of x-ray beams in a multiplexing fashion.

    IMAGE RECONSTRUCTION METHOD FOR COMPUTED TOMOGRAPHY
    7.
    发明申请
    IMAGE RECONSTRUCTION METHOD FOR COMPUTED TOMOGRAPHY 审中-公开
    计算机断层摄影的图像重建方法

    公开(公告)号：WO2017205379A2

    公开(公告)日：2017-11-30

    申请号：PCT/US2017/034011

    申请日：2017-05-23

    Applicant: RENSSELAER POLYTECHNIC INSTITUTE

    Inventor： WANG, Ge ,  CONG, Wenxiang

    IPC: A61B6/00 ,  A61B6/03 ,  G06T5/00

    CPC classification number: A61B6/00 ,  A61B6/03 ,  A61B6/032 ,  A61B6/482 ,  G06T11/003

    Abstract: Systems and methods for reconstructing images for computed tomography are provided. Image reconstruction can be based on a realistic polychromatic physical model, and can include use of both an analytical algorithm and a single-variable optimization method. The optimization method can be used to solve the non-linear polychromatic X- ray integral model in the projection domain, resulting in an accurate decomposition for sinograms of two physical basis components.

    Abstract translation: 提供了用于重建计算机断层摄影图像的系统和方法。 图像重建可以基于现实的多色物理模型，并且可以包括分析算法和单变量优化方法的使用。 该优化方法可用于求解投影域中的非线性多色X射线积分模型，从而对两个物理基础分量的正弦图进行准确分解。

    ENERGY-SENSITIVE MULTI-CONTRAST COST-EFFECTIVE CT SYSTEM
    8.
    发明申请
    ENERGY-SENSITIVE MULTI-CONTRAST COST-EFFECTIVE CT SYSTEM 审中-公开
    能量敏感的多对比度成本有效的CT系统

    公开(公告)号：WO2017143247A1

    公开(公告)日：2017-08-24

    申请号：PCT/US2017/018456

    申请日：2017-02-17

    Applicant: RENSSELAER POLYTECHNIC INSTITUTE

    Inventor： WANG, Ge ,  CONG, Wenxiang

    IPC: A61B6/00 ,  A61B6/03

    CPC classification number: A61B6/484 ,  A61B6/032

    Abstract: Systems and methods for obtaining scattering images during computed tomography (CT) imaging are provided. Two gratings or grating layers can be disposed between the object to be imaged and the detector, and the gratings or grating layers can be arranged such that primary X-rays are blocked while scattered X-rays that are deflected as they pass through the object to be imaged reach the detector to generate the scattering image.

    Abstract translation: 提供了用于在计算机断层摄影（CT）成像期间获得散射图像的系统和方法。 两个光栅或光栅层可以设置在要被成像的物体和检测器之间，并且光栅或光栅层可以被布置成使得主X射线被阻挡，而散射的X射线在它们穿过物体时偏转到 成像到达探测器产生散射图像。

    SPECTRAL X-RAY DETECTORS WITH DYNAMIC ELECTRONIC CONTROL AND COMPUTATIONAL METHODS
    9.
    发明申请
    SPECTRAL X-RAY DETECTORS WITH DYNAMIC ELECTRONIC CONTROL AND COMPUTATIONAL METHODS 审中-公开
    具有动态电子控制和计算方法的光谱X射线探测器

    公开(公告)号：WO2016118960A1

    公开(公告)日：2016-07-28

    申请号：PCT/US2016/014769

    申请日：2016-01-25

    Applicant: RENSSELAER POLYTECHNIC INSTITUTE

    Inventor： WANG, Ge ,  CONG, Wenxiang ,  SHI, Zaifeng

    IPC: G01T1/36 ,  G01T1/29 ,  G01T1/15

    CPC classification number: G01T1/241

    Abstract: Novel and advantageous methods and systems for performing computed tomography (CT) imaging are disclosed. Electrodes can be connected to appropriate surface sites of a detector element of a CT scanner to capture nearby electron-hole pairs generated by X-rays received on the detector element. This detection can be performed in current- integrating/energy -integrating mode.

    Abstract translation: 公开了用于执行计算机断层摄影（CT）成像的新颖和有利的方法和系统。 电极可以连接到CT扫描器的检测器元件的适当的表面部位，以捕获在检测器元件上接收的X射线产生的附近的电子 - 空穴对。 该检测可以在电流积分/能量集成模式下进行。

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