Abstract:
Systems and methods are disclosed that include generating a plasma treatment and applying the plasma treatment to end contact surfaces of a first profile and a second profile in a sterile environment, manipulating at least one of the first profile and the second profile to force contact between the end contact surface of the first profile and the end contact surface of the second profile to permanently connect, join, or weld the end contact surfaces of the first profile and the second profile together, thereby forming a sterile connection between the first profile and a second profile.
Abstract:
A manufacturing article adapted for use in the production of pharmaceuticals comprising a tray comprising a base having a top surface; and a manifold extending from the top surface of the base, the manifold comprising a sidewall and an upper surface, the upper surface further comprising a channel, wherein, when viewed from the top surface, the base has an area, AB, the upper surface of the manifold has an area AM, and AB > AM, and wherein the base is adapted to support a plurality of vessels each adapted to contain a fluid.
Abstract:
A fluid flow sinker including a body having a generally cylindrical sidewall, a first end, a second end, and an aperture extending between the first and second ends; and a fluid passageway disposed on the first end and extending from the generally cylindrical sidewall to the aperture, wherein the fluid flow sinker is adapted to receive a tube in communication with the aperture.
Abstract:
The present application is directed to closure assemblies, and particularly closure assemblies for closing an opening in a vessel. In particular embodiments, the closure assemblies described herein can have a first ring having a top surface, an inner surface and an outer surface, wherein the outer surface comprises threading, wherein the first ring comprises a first flange having a top surface extending radially inward from the inner surface of the first ring a distance of F L , and wherein the top surface of the first flange is spaced apart from the top surface of the first ring by a distance F H , and wherein a ratio of F H :F L is greater than 1.
Abstract:
The present application is directed to cap assemblies and particularly, cap assembly for closing an opening in a vessel, the cap assembly including a stopper including an polymer body adapted to fit an opening of a vessel, the stopper also including a tubular portion which defines an internal passageway extending through the polymer body; and a rigid cap attached to and integral with the stopper, wherein the cap is adapted to engage the vessel and provide a sealing force between the stopper and the vessel.
Abstract:
A sanitary fluid transport coupling can include a plurality of fluid conduits, each fluid conduit having a distal end and a proximal end, a support element adapted to secure a spaced relationship between the plurality of second conduits at the distal end of the plurality of fluid conduits, and an overmolded element disposed adjacent the support element. The overmolded element can form a fitting that can form a fluid connection with another fluid conduit, fluid container, or isolated environment.
Abstract:
Embodiments of the present disclosure are directed to a fluid connection including a plurality of flexible polymeric tubes; an integral fluid connector coupled to and in fluid communication with each of the plurality of tubes; and a shell disposed over and encapsulating the fluid connector. The fluid connection surprisingly exhibiting significant increases in the working pressure, particularly in biopharmaceutical fluid transfer systems.
Abstract:
The present application is directed to a packaging container including a body including; a first portion including a coupling feature; a second portion including a coupling feature and complementary to the first portion; and a hinge portion coupling the first portion to the second portion adapted to move the packaging container from an open position to a closed position around a product, where the first portion and the second portion combine to form a void port in the closed position.