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    APPARATUS AND METHODS FOR TITRATING CALORIC VESTIBULAR STIMULATION
    1.
    发明申请
    APPARATUS AND METHODS FOR TITRATING CALORIC VESTIBULAR STIMULATION 审中-公开
    用于治疗卡路里血管刺激的装置和方法

    公开(公告)号：WO2012083102A1

    公开(公告)日：2012-06-21

    申请号：PCT/US2011/065328

    申请日：2011-12-16

    Applicant: SCION NEUROSTIM, LLC ,  ROGERS, Lesco L. ,  SMITH, Lanty L. ,  BLACK, Robert D.

    Inventor： ROGERS, Lesco L. ,  SMITH, Lanty L. ,  BLACK, Robert D.

    IPC: A61F7/00

    CPC classification number: A61F7/12 ,  A61B2018/00875 ,  A61F7/007 ,  A61F2007/0005 ,  A61F2007/0075 ,  A61F2007/0093 ,  A61F2007/0095 ,  A61F2007/0096 ,  A61F2007/0296 ,  A61N1/36036 ,  A61N2/002 ,  A61N2/006

    Abstract: A device for delivering caloric vestibular stimulation to an individual, includes: (a) an earpiece configured to be at least partially insertable into the ear canal of the individual for delivering a first thermal stimulus; (b) an input unit for receiving a user input indicating efficacy of said first thermal stimulus, and (c) a controller operatively associated with said earpiece and said input unit for: (i) controlling said earpiece to provide said first thermal stimulus, and (ii) receiving a signal corresponding to the user input and generating a control signal to control the earpiece and delivering a subsequent thermal stimulus different from said first thermal stimulus. In some embodiments, each thermal stimulus is an actively controlled time varying waveform stimulus.

    Abstract translation: 用于向个人输送热量前庭刺激的装置包括：（a）耳机，其被配置为至少部分地插入到个体的耳道中，用于传送第一热刺激; （b）用于接收指示所述第一热刺激的功效的用户输入的输入单元，以及（c）与所述耳机和所述输入单元可操作地相关联的控制器，用于：（i）控制所述耳机以提供所述第一热刺激，以及 （ii）接收与所述用户输入相对应的信号并产生控制信号以控制所述耳机并传送不同于所述第一热刺激的后续热刺激。 在一些实施例中，每个热刺激是主动控制的时变波形刺激。

    DEVICES AND METHODS FOR VESTIBULAR AND/OR CRANIAL NERVE STIMULATION
    4.
    发明申请
    DEVICES AND METHODS FOR VESTIBULAR AND/OR CRANIAL NERVE STIMULATION 审中-公开
    用于前庭和/或丘脑神经刺激的装置和方法

    公开(公告)号：WO2011075574A1

    公开(公告)日：2011-06-23

    申请号：PCT/US2010/060771

    申请日：2010-12-16

    Applicant: SCION NEUROSTIM, LLC ,  SMITH, Lanty L. ,  ROGERS, Lesco L.

    Inventor： SMITH, Lanty L. ,  ROGERS, Lesco L.

    IPC: A61F7/12

    CPC classification number: A61F7/12 ,  A61F7/007 ,  A61F2007/0005 ,  A61F2007/0075 ,  A61F2007/0093 ,  A61F2007/0096

    Abstract: An in-ear stimulator for administering thermal stimulation to the ear canal of a subject includes (a) an earpiece configured to be insertable into the ear canal of said subject, the earpiece having an outer surface and an internal cavity formed therein, the internal cavity having an inner surface; and (b) at least one thermoelectric device thermally coupled to the earpiece internal cavity inner surface.

    Abstract translation: 用于向受试者的耳道给予热刺激的耳内刺激器包括：（a）耳机，其被构造成可插入所述受试者的耳道中，所述耳机具有外表面和 其中形成有内腔，所述内腔具有内表面; 和（b）至少一个与耳机内腔内表面热耦合的热电装置。

    SYSTEMS, DEVICES AND METHODS FOR BILATERAL CALORIC VESTIBULAR STIMULATION
    5.
    发明申请
    SYSTEMS, DEVICES AND METHODS FOR BILATERAL CALORIC VESTIBULAR STIMULATION 审中-公开
    系统，装置和方法用于双侧卡路里血管刺激

    公开(公告)号：WO2012083126A1

    公开(公告)日：2012-06-21

    申请号：PCT/US2011/065396

    申请日：2011-12-16

    Applicant: SCION NEUROSTIM, LLC ,  ROGERS, Lesco L. ,  SMITH, Lanty L. ,  BLACK, Robert D.

    Inventor： ROGERS, Lesco L. ,  SMITH, Lanty L. ,  BLACK, Robert D.

    IPC: A61F7/00

    CPC classification number: A61F7/12 ,  A61B2018/00875 ,  A61F7/007 ,  A61F2007/0005 ,  A61F2007/0075 ,  A61F2007/0093 ,  A61F2007/0095 ,  A61F2007/0096 ,  A61F2007/0296 ,  A61N1/36036 ,  A61N2/002 ,  A61N2/006

    Abstract: An in-ear stimulation device for administering caloric stimulation to the ear canal of a subject includes (a) first and second earpieces configured to be insertable into the ear canals of the subject; (b) at least first and second thermoelectric devices thermally coupled to respective ones of the first and second earpieces; (c) a first heat sink thermally coupled to the first thermoelectric device opposite the first earpiece and a second heat sink thermally coupled to the second thermoelectric device opposite the second earpiece; and (d) a controller comprising a waveform generator in communication with the first and second thermoelectric devices, the waveform generator configured to generate a first control signal to control a first caloric output to the first thermoelectric device and a second control signal to control a second caloric output to the second caloric device.

    Abstract translation: 用于对受试者的耳道施加热量刺激的入耳式刺激装置包括：（a）被配置为可插入对象的耳道中的第一和第二耳机; （b）至少第一和第二热电装置热耦合到第一和第二耳机中的相应的一个; （c）热耦合到与第一耳机相对的第一热电装置的第一散热器和与第二耳机相对的与第二热电装置热耦合的第二散热器; 和（d）包括与第一和第二热电装置连通的波形发生器的控制器，所述波形发生器被配置为产生第一控制信号以控制到第一热电装置的第一热量输出和第二控制信号以控制第二热电装置 热量输出到第二热量装置。

    SYSTEMS, DEVICES AND METHODS FOR NEUROSTIMULATION
    8.
    发明申请
    SYSTEMS, DEVICES AND METHODS FOR NEUROSTIMULATION 审中-公开

    公开(公告)号：WO2019173468A1

    公开(公告)日：2019-09-12

    申请号：PCT/US2019/020938

    申请日：2019-03-06

    Applicant: SCION NEUROSTIM, LLC

    Inventor： BLACK, Robert D. ,  SMITH, Lanty L. ,  ROGERS, Lesco L.

    IPC: A61N1/04 ,  A61N1/36 ,  A61F7/12 ,  A61F7/00 ,  A61N2/00

    Abstract: Systems, devices, and methods for neurostimulation via vestibular stimulation are described. One example is a device for administering thermal stimulation to an ear canal of a subject. The device may include an earpiece configured to be at least partially insertable into the ear canal of the subject; a thermoelectric device thermally coupled to the earpiece and configured to heat and/or cool the earpiece to thereby heat and/or cool the ear canal of the subject; and a controller configured to administer a selected treatment plan including administering a caloric vestibular stimulation (CVS) stimulus to the ear canal of the subject in a condition-treatment effective amount during a first treatment interval. The treatment plan may be effective to produce a durable improvement in at least one symptom of the condition for a time of at least 1 week following cessation of the administering.

    SYSTEMS, DEVICES AND METHODS FOR NEUROSTIMULATION HAVING A MODULATION OF PACKETS
    9.
    发明申请
    SYSTEMS, DEVICES AND METHODS FOR NEUROSTIMULATION HAVING A MODULATION OF PACKETS 审中-公开
    用于包装调制的神经细胞的系统，装置和方法

    公开(公告)号：WO2017040739A2

    公开(公告)日：2017-03-09

    申请号：PCT/US2016/049824

    申请日：2016-09-01

    Applicant: SCION NEUROSTIM, LLC

    Inventor： BLACK, Robert D. ,  SMITH, Lanty L. ,  ROGERS, Lesco L.

    IPC: A61N1/36 ,  A61F7/12

    CPC classification number: A61N1/36036 ,  A61B6/037 ,  A61F7/12 ,  A61F2007/0005 ,  A61F2007/0093 ,  A61F2007/126 ,  A61N1/0456 ,  A61N1/0484 ,  A61N1/0526 ,  A61N1/36021 ,  A61N1/36025

    Abstract: A method of neurostimulation may include delivering an electrical signal to a plurality of electrodes connected to a patient. The electrical signal may include a plurality of spaced-apart packets of electrical pulses. The method may include modulating at least one of a quantity of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, a width in time of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, an amplitude in voltage of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, a separation in time between adjacent ones of the plurality of electrical pulses within ones of the plurality of packets of electrical pulses, and a separation in time between adjacent ones of the plurality of packets of electrical pulses to modulate the electrical signal.

    Abstract translation: 神经刺激的方法可以包括将电信号递送到连接到患者的多个电极。 电信号可以包括多个间隔开的电脉冲分组。 该方法可以包括调制多个电脉冲分组中的多个电脉冲中的多个电脉冲中的至少一个，多个电脉冲分组中的多个电脉冲的时间宽度， 在多个电脉冲分组中的多个电脉冲之间的多个电脉冲的电压幅度，多个电脉冲分组之间的多个电脉冲中的相邻电脉冲之间的时间间隔，以及多个电脉冲之间的时间间隔 多个电脉冲分组中的相邻的电脉冲分组以调制电信号。

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